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From pills to bio-electronics: a wearable anti-inflammatory treatment for prevention of Peripheral Arterial Disease.

Project description

Wearable bio-electronic device for the treatment of peripheral arterial disease

Life-threatening peripheral arterial disease (PAD) affects 200 million people worldwide and is the third cause of cardiovascular morbidity. This condition is associated with the arteries narrowing, reduced blood flow, chronic pain and critical limb ischaemia. PAD’s progression leads to gangrene, amputations and even death. Austrian company AURIMOD has developed a wearable device with the potential to improve all symptoms of PAD. The device is applied to the patient’s ear and sends specific electrical stimulation to the auricular branches of the vagus nerve. This non-invasive treatment might prevent PAD complications, including chronic wounds and amputations. The EU-funded AuriMod project will focus on product development, a business model for it and the potential supply chain.

Objective

Peripheral Arterial Disease (PAD) is a life-threatening disease affecting 200 M people in the world (40.5 M only in EU) and represents the third cause of world cardiovascular morbidity. PAD is a chronic condition generated by the narrowing of arteries, which reduces the normal blood flow and triggers a wide range of manifestations mostly in the lower limbs, from chronic pain to critical limb ischemia. PAD’s progression can lead to chronic wounds, gangrene, amputation, and in most severe cases, death. There is no current solution able to target the broad range of symptoms and complications related to PAD. AuriMod is a wearable device for non-invasive auricular stimulation of the vagus nerve that is capable of treating all symptoms of PAD, avoiding conventional drugs’ side effects and preventing complications including chronic wounds and consequent amputations. Applied to the patient’s ear, AuriMod sends specific electrical stimulation to the auricular branches of the vagus nerve, delivering a patient-tailored therapy that will improve the quality of life of PAD patients. This Phase 1 project will mainly focus on planning further product development, verifying the current supply chain, evaluating the business model and commercialisation plan. The overall innovation project will enable to optimise AuriMod device, conduct clinical trials to validate safety and effectiveness of AuriMod-based therapy and acquire all certifications required for AuriMod’s commercialisation.

Fields of science (EuroSciVoc)

Programme(s)

Topic(s)

Funding Scheme

SME-1 - SME instrument phase 1

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Call for proposal

(opens in new window) H2020-SMEInst-2016-2017

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Coordinator

AURIMOD GMBH
Net EU contribution
€ 50 000,00
Address
MODECENTERSTRASSE 22/D29
1030 WIEN
Austria
SME
Yes
Region
Ostösterreich Wien Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
€ 71 429,00