Project description
Research training programme for management of patients with end-stage kidney disease
Peritoneal dialysis (PD) is a life-saving renal replacement therapy for patients suffering from end-stage kidney disease. There is an urgent need for individualised PD approaches as these patients have an increased risk of cardiovascular disease linked to high mortality. Funded by the Marie Skłodowska-Curie Actions programme, the IMPROVE-PD project aims to engage leading academic and industrial researchers in creating a training platform to understand the mechanisms of inflammation-driven cardiovascular disease in PD patients and developing individualised therapies for those at risk. The objective is to provide training for 15 young scientists who are going to work in a multidisciplinary European PhD-level training programme that includes leading academic, clinical and industrial partners.
Objective
Peritoneal dialysis (PD) is an underused life saving renal replacement therapy for end-stage kidney disease. Nevertheless, PD patients remain at high risk for poor outcome, most notably excessive risk of cardiovascular disease. There is an unmet need for a risk-adjusted individualized PD approach. The IMPROVE-PD consortium provides 15 Early Stage Researchers (ESRs) in 11 partner institutes located in 7 different countries a state-of-the-art, multidisciplinary and intersectoral pan- European training programme including input from academic, clinical and industrial stakeholders. Network-wide and local training activities, individual research projects, intersectoral secondments and short laboratory visits will provide key generic skills and will prepare ESRs for future roles as highly skilled researchers in Europe. Well-phenotyped patient cohorts, and novel experimental models and techniques will be exploited by the ESRs, mentored by an excellent supervisory team, to improve future management of the PD patient at risk. This joint effort encourages productive collaboration between industrial and academic sectors though integrated projects and shared goals. Key findings will be communicated to a broad range of stakeholders through state of the art methods. IMPROVE-PD will give rise to a new generation of experts in PD with outstanding interdisciplinary research skills, intersectoral understanding and with perspective to pursue their careers in this scientific and industrial field. It will enable timely identification of the PD patient at high risk for adverse outcome, develop understanding of underlying pathomechanisms, and within an iterative process between research groups foster the development of innovative approaches to individualized treatment by targeting revealed pathomechanisms. Through these approaches, the ITN will achieve refinement of PD fluids, PD therapy and cardiovascular risk reduction.
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Programme(s)
Coordinator
28006 Madrid
Spain
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Participants (11)
CF24 0DE Cardiff
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1020 Wien
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75654 Paris
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ST5 5BG Keele
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Participation ended
1040 Wien
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1348 Louvain La Neuve
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69120 Heidelberg
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1081 HV Amsterdam
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1090 Wien
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
28049 Madrid
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1090 Wien
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Partners (11)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
25198 Lleida
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
61-701 Poznan
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
5000 Adelaide
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
BS10 5NB Bristol
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
9000 Gent
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
28046 Madrid
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1090 Wien
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
PE2 6FZ Peterborough
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
61352 Bad Homburg
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
13595 Berlin
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1405 EE Bussum
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