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Mass-transfer independent long-term implantable biosensors

Deliverables

Job announcements

Job announcements published on EU employment sites , partner websites, academic networks

Delivery School 2

Report on the second ImplantSens School

Delivery School 3

Report on the third ImplantSens School

Outreach activities

Report on outreach activities

Update outreach activities

Updated report on outreach activities

Delivery of school 1

Report on the first ImplantSens School

Publications

Unusual long-term stability of enzymatic bioelectrocatalysis in organic solvents

Author(s): S. Bichon, P. Staigre, S. Gounel, T. Safarik, C. Carucci, A. Kuhn, N. Mano
Published in: Journal of Catalysis, Issue 428, 2023, Page(s) 115163, ISSN 0021-9517
Publisher: Academic Press
DOI: 10.1016/j.jcat.2023.115163

Multiscale modelling of diffusion and enzymatic reaction in porous electrodes in Direct Electron Transfer mode

Author(s): Le, Tien Dung; Lasseux, Didier; Zhang, Lin; Carucci, Cristina; Gounel, Sebastien; Bichon, Sabrina; Lorenzutti, Francesca; Kuhn, Alexander; Šafarik, Tatjana; Mano, Nicolas
Published in: Chemical Engineering Science, Issue 248, 2022, Page(s) 117157, ISSN 0009-2509
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.ces.2021.117157

Splicing the active phases of copper/cobalt-based catalysts achieves high-rate tandem electroreduction of nitrate to ammonia

Author(s): He, Wenhui; Zhang, Jian; Dieckhöfer, Stefan; Varhade, Swapnil; Brix , Ann Cathrin; Lielpetere, Anna; Seisel, Sabine; Junqueira, João R. C.; Schuhmann, Wolfgang
Published in: Nature Communications, Issue 13, 2022, Page(s) 1129, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28728-4

Bioelectrocatalytic CO2 Reduction by Redox Polymer-Wired Carbon Monoxide Dehydrogenase Gas Diffusion Electrodes

Author(s): Becker, Jana M.; Lielpetere, Anna; Szczesny, Julian; Junqueira, João R. C.; Rodríguez-Maciá, Patricia; Birrell, James A.; Conzuelo, Felipe; Schuhmann, Wolfgang
Published in: ACS Applied Materials & Interfaces, Issue 14, 2022, Page(s) 46421−46426, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.2c09547

Coupled immobilized bi-enzymatic flow reactoremploying cofactor regeneration of NAD+ using athermophilic aldehyde dehydrogenase and lactatedehydrogenase

Author(s): K. Shortall, S. Arshi, S. Bendl, X. Xiao, S. Belochapkine, D. Demurtas, T. Soulimane, E.Magner
Published in: Green Chemistry, Issue 25, 2023, Page(s) 4553-4564, ISSN 1463-9270
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3gc01536j

Portable Prussian blue-based sensor for bacterial detection in urine

Author(s): C. Psotta, V. Chaturvedi, J. F. Gonzalez-Martinez, J. Sotres, M. Falk.
Published in: Sensors, Issue 23, 2023, Page(s) 388, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s23010388

Electronic Tongue for Direct Assessment of SARS-CoV-2-Free and Infected Human Saliva—A Feasibility Study

Author(s): Falk, Magnus; Psotta, Carolin; Cirovic, Stefan; Ohlsson, Lars; Shleev, Sergey
Published in: Biosensors, Issue 13, 2023, Page(s) 717, ISSN 2079-6374
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios13070717

A biophotoelectrode based on boronic acid-modified Chlorella vulgaris cells integrated within a redox polymer

Author(s): Herrero-Medina, Zaida; Wang, Panpan; Lielpetere, Anna; Bashammakh, Abdulaziz S.; Alyoubi, Abdulrahman O.; Katakis, Ioanis; Conzuelo, Felipe; Schuhmann, Wolfgang
Published in: Bioelectrochemistry, Issue 146, 2022, Page(s) 108128, ISSN 1567-5394
Publisher: Elsevier BV
DOI: 10.1016/j.bioelechem.2022.108128

Polymer coating for improved redox-polymer-mediated enzyme electrodes: A mini-review

Author(s): X. Xiao, X. Yan, E.Magner, J. Ulstrup
Published in: Electrochemistry Communications, Issue 124, 2021, Page(s) 106931, ISSN 1388-2481
Publisher: Elsevier BV
DOI: 10.1016/j.elecom.2021.106931

Electrochemical Studies of Galactose Oxidase

Author(s): Carina Figueiredo, Antonio L. De Lacey, Marcos Pita
Published in: Electrochemical Science Advances, 2021, ISSN 2698-5977
Publisher: Wiley VCH
DOI: 10.1002/elsa.202100171

Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids

Author(s): Magnus Falk, Carolin Psotta, Stefan Cirovic, Sergey Shleev
Published in: Sensors, Issue 20/21, 2020, Page(s) 6352, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s20216352

On the Mediated Electron Transfer of Immobilized Galactose Oxidase for Biotechnological Applications

Author(s): Zhao, Fangyuan; Brix, Ann Cathrin; Lielpetere, Anna; Schuhmann, Wolfgang; Conzuelo, Felipe
Published in: Chemistry - a European Journal, 2022, Page(s) e202200868, ISSN 1521-3765
Publisher: Wiley VCH
DOI: 10.1002/chem.202200868

Electrochemical glucose biosensor based on an osmium redox polymer and glucose oxidase grafted to carbon nanotubes: A design-of-experiments optimisation of current density and stability

Author(s): Kavita Jayakumar, Richard Bennett, Dónal Leech
Published in: Electrochimica Acta, Issue 371, 2021, Page(s) 137845, ISSN 0013-4686
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.electacta.2021.137845

An Oxygen Insensitive Amperometric Glucose Biosensor Based on An Engineered Cellobiose Dehydrogenase: Direct versus Mediated Electron Transfer Responses

Author(s): Jayakumar, Kavita; Reichhart, Thomas; Schulz, Christopher; Ludwig, Roland; Felice, Alfons K.G.; Leech, Donal
Published in: ChemElectroChem, Issue 21960216, 2022, Page(s) e202200418, ISSN 2196-0216
Publisher: Wiley-VCH
DOI: 10.1002/celc.202200418

Continuous ex vivo glucose sensing in human physiological fluids using an enzymatic sensor in a vein replica

Author(s): Psotta, Carolin; Cirovic, Stefan; Gudmundsson, Petri; Falk, Magnus; Mandal, Tanushree; Reichhart, Thomas; Leech, Donal; Ludwig, Roland; Kittel, Roman; Schuhmann, Wolfgang; Shleev, Sergey
Published in: Bioelectrochemistry, Issue 152, 2023, Page(s) 108441, ISSN 1567-5394
Publisher: Elsevier BV
DOI: 10.1016/j.bioelechem.2023.108441

Cross-Linkable Polymer-Based Multi-layers for Protecting Electrochemical Glucose Biosensors against Uric Acid, Ascorbic Acid, and Biofouling Interferences

Author(s): Lielpetere, Anna; Jayakumar, Kavita; Leech, Dónal; Schuhmann, Wolfgang
Published in: ACS - Sensors, Issue 8, 2023, Page(s) 1756–1765, ISSN 2379-3694
Publisher: American Chemical Society
DOI: 10.1021/acssensors.3c00050

Rational Design of a Photosystem I Photoanode for the Fabrication of Biophotovoltaic Devices

Author(s): Panpan Wang, Fangyuan Zhao, Anna Frank, Sarra Zerria, Anna Lielpetere, Adrian Ruff, Marc M. Nowaczyk, Wolfgang Schuhmann, Felipe Conzuelo
Published in: Advanced Energy Materials, Issue 11, 2021, Page(s) 2102858, ISSN 1614-6840
Publisher: Wiley VCH
DOI: 10.1002/aenm.202102858

Wiring of bilirubin oxidases with redox polymers on gas diffusion electrodes for increased stability of self-powered biofuel cells-based glucose sensing

Author(s): Becker, Jana M.; Lielpetere, Anna; Szczesny, Julian; Bichon, Sabrina; Goune, Sebastien; Mano, Nicolas; Schuhmann, Wolfgang
Published in: Bioelectrochemistry, Issue 149, 2023, Page(s) 108314, ISSN 1567-5394
Publisher: Elsevier BV
DOI: 10.1016/j.bioelechem.2022.108314

Assembling a low‐volume biofuel cell on a screen‐printed electrode for glucose sensing

Author(s): Becker, Jana M.; Lielpetere, Anna; Szczesny, Julian; Ruff, Adrian; Conzuelo, Felipe; Schuhmann, Wolfgang
Published in: Electroanalysis, 2022, ISSN 1521-4109
Publisher: Wiley-VCH GmbH
DOI: 10.1002/elan.202200084

An oxygen-insensitive amperometric galactose biosensor based on galactose oxidase co-immobilized with an Os-complex modified redox polymer

Author(s): Figueiredo, Carina; Garcia-Ortega, Andrea; Mandal, Tanushree; Lielpetere, Anna; Cervantes, Fadia; Demurtas, Denise; Magner, Edmond; Plou, Francisco J.; Schuhmann, Wolfgang; Leech, Donal; Pita, Marcos; De Lacey, Antonio L.
Published in: Electrochimica Acta, Issue 472, 2023, Page(s) 143438, ISSN 0013-4686
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.electacta.2023.143438

Bottom‐up designed porous coaxial twin‐electrodes for efficient redox cycling

Author(s): T. Šafarik, A. Karajić, S. Reculusa, P. N. Bartlett, N. Mano, A. Kuhn
Published in: Advanced functional Materials, Issue 33, 2023, Page(s) 2210638, ISSN 1616-3028
Publisher: Wiley-VCH GmbH
DOI: 10.1002/adfm.202210638

Tethering zwitterionic polymer coatings to mediated glucose biosensor enzyme electrodes can decrease sensor foreign body response yet retain sensor sensitivity to glucose

Author(s): Jayakumar, Kavita; Lielpetere, Anna; Domingo-Lopez, Daniel A.; Levey, Ruth E.; Duffy , Garry P.; Schuhmann, Wolfgang; Leech, Donal
Published in: Biosensors and Bioelectronics, Issue 219, 2023, Page(s) 114815, ISSN 0956-5663
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2022.114815

Engineering the Turnover Stability of Cellobiose Dehydrogenase toward Long-Term Bioelectronic Applications

Author(s): Andreas F. Geiss, Thomas M. B. Reichhart, Barbara Pejker, Esther Plattner, Peter L. Herzog, Christopher Schulz, Roland Ludwig, Alfons K. G. Felice, Dietmar Haltrich
Published in: ACS Sustainable Chem. Eng., Issue 9, 2021, Page(s) 7086–7100, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.1c01165

Catalytic Biosensors Operating under Quasi-Equilibrium Conditions for Mitigating the Changes in Substrate Diffusion

Author(s): Muhs, Anna; Bobrowski, Tim; Lielpetere, Anna; Schuhmann, Wolfgang
Published in: Angewandte Chemie - International Edition, Issue 61, 2022, Page(s) e202211559, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202211559

Enhancing the catalytic current response of H2 oxidation gas diffusion bioelectrodes using an optimized viologen-based redox polymer and [NiFe] hydrogenase

Author(s): Lielpetere, Anna; Becker, Jana M.; Szczesny, Julian; Conzuelo, Felipe; Ruff, Adrian; Birrell, James; Lubitz, Wolfgang; Schuhmann, Wolfgang
Published in: Electrochemical Science Advances, 2021, Page(s) e2100100, ISSN 2698-5977
Publisher: Wiley-VCH GmbH
DOI: 10.1002/elsa.202100100

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