Project description
Advanced implantable glucose biosensors
Being able to continuously monitor the in vivo levels of analytes such as glucose is of great interest in medicine especially in the context of chronic diseases. However, implantable biosensors present significant challenges due to inflammatory responses against the sensor and the dynamic environment of living tissues. The aim of the EU-funded ImplantSens project is to train young scientists in the field of biosensors to tackle such unmet technological issues. The experimental focus of the project is to advance enzymatic glucose sensors and combine nanomaterials towards improved sensor biocompatibility and accuracy.
Objective
ImplantSens will develop long‐term stable implantable electrochemical biosensors by overcoming mass‐transport limited sensing schemes. This is the major unsolved problem due to the formation of capsules by the foreign body response upon implantation of a sensor. ImplantSens will not only contribute to the painless long‐term monitoring of glucose levels for diabetic patients but also to the development of future implantable sensors for the management of other chronic diseases. 11 ESR will be engaged in all tasks of this scientific chain, thus being trained in the fundamentals of bioelectrochemistry, enzyme engineering, electrode design as well as biocompatibility. Training of the fellows will be performed via an innovative program based on a blended learning concept and will take place at the host institutions, via secondments, workshops, schools and e-learning elements. The scientific training will be completed by training of complementary skill with respect to management, fund raising, IPR and scientific communication. The consortium consists of 7 leading scientists in Europe with the necessary expertise to target this ambitious goal supported by 4 SMEs. ÍmplantSens will improve the availability of a highly skilled workforce for European industries and research strongly needed for at the beginning of the 4th industrial revolution.
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Coordinator
44801 Bochum
Germany