INtegrating Magnetic Resonance SPectroscopy and Multimodal Imaging for Research and Education in MEDicine

Información del proyecto

INSPiRE-MED

Identificador del acuerdo de subvención: 813120

DOI

10.3030/813120

Proyecto cerrado

Fecha de la firma de la CE 17 Agosto 2018

Fecha de inicio 1 Enero 2019

Fecha de finalización 30 Junio 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 3 946 286,03

Aportación de la UE

€ 3 946 286,03

Coordinado por

UNIVERSITE LYON 1 CLAUDE BERNARD
France

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Websites, patent fillings, videos etc. (3)

Communication plan
INSPiRE-MED website
Final exploitation strategy

Documents, reports (2)

Outreach report: summary of ESRs public engagement activities

Outreach report summary of ESRs public engagement activities

Final report on training programme implementation

Publicaciones

Peer reviewed articles (26)

Quantification of MR spectra by deep learning in an idealized setting: Investigation of forms of input, network architectures, optimization by ensembles of networks, and training bias

Autores: Rizzo R, Dziadosz M, Kyathanahally SP, Shamaei A, Kreis R
Publicado en: Magnetic Resonance in Medecine, Edición Volume89, Edición5, 2022, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29561

icobrain ms 5.1: Combining unsupervised and supervised approaches for improving the detection of multiple sclerosis lesions

Autores: Rakić M, Vercruyssen S, Van Eyndhoven S, de la Rosa E, Jain S, Van Huffel S, Maes F, Smeets D, Sima DM
Publicado en: NeuroImage: Clinical, Edición 31, 2021, Página(s) 102707, ISSN 2213-1582
Editor: Elsevier BV
DOI: 10.1016/j.nicl.2021.102707

Multi-echo single-shot spectroscopy combined with simultaneous 2D model fitting for fast and accurate measurement of metabolite-specific concentrations and T2 relaxation times

Autores: Rudy Rizzo, Roland Kreis
Publicado en: NMR in Biomedicine, 2023, ISSN 0952-3480
Editor: John Wiley & Sons Inc.
DOI: 10.1002/nbm.5016

Post-acquisition water-signal removal in 3D water‐unsuppressed 1H-MR spectroscopic imaging of the prostate.

Autores: Stamatelatou A, Sima DM, Van Huffel S, van Asten JJ, Heerschap A, Scheenen TW
Publicado en: Magnetic Resonance in Medicine, Edición Volume89, Edición5, 2022, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29565

A comparison of non-negative matrix underapproximation methods for the decomposition of magnetic resonance spectroscopy data from human brain tumors

Autores: Gulnur Ungan, Carles Arús, Alfredo Vellido, Margarida Julià-Sapé
Publicado en: nmr in biomedicine, 2023, ISSN 0952-3480
Editor: John Wiley & Sons Inc.
DOI: 10.1002/nbm.5020

Ensemble Learning for Multiple Sclerosis Disability Estimation Using Brain Structural Connectivity

Autores: Berardino Barile, Aldo Marzullo, Claudio Stamile, Françoise Durand-Dubief, and Dominique Sappey-Marinier
Publicado en: Brain Connectivity, Edición VOLUME 12, ISSUE 5 / JUNE 2022, 2022, ISSN 2158-0022
Editor: Mary Ann Liebert, Inc., publishers
DOI: 10.1089/brain.2020.1003

Deuterium echo-planar spectroscopic imaging (EPSI) in the human liver in vivo at 7 T

Autores: Kyung Min Nam, Ayhan Gursan, Alex A. Bhogal, Jannie P. Wijnen, Dennis W. J. Klomp, Jeanine J. Prompers, Arjan D. Hendriks
Publicado en: Magnetic Resonance in Medicine, 2023, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29696

MP-PCA denoising for diffusion MRS data: promises and pitfalls

Autores: Mosso J, Simicic D, Şimşek K, Kreis R, Cudalbu C, Jelescu IO.
Publicado en: Neuroimage, 2022, Página(s) Volume 263, November 2022, 119634, ISSN 1053-8119
Editor: Academic Press
DOI: 10.1016/j.neuroimage.2022.119634

Immune System-Related Changes in Preclinical GL261 Glioblastoma under TMZ Treatment: Explaining MRSI-Based Nosological Imaging Findings with RT-PCR Analyses.

Autores: Pilar Calero-Pérez; Shuang Wu; Carles Arús; Ana Paula Candiota
Publicado en: Cancers, Edición 13(11), May 2021, 2021, Página(s) 2663, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13112663

Classification of multiple sclerosis clinical profiles using machine learning and grey matter connectome.

Autores: Barile B., Ashtari P., Stamile C., Marzullo A., Maes F., Durand-Dubief F., Van Huffel S., Sappey-Marinier D.,
Publicado en: Frontiers Robotics AI, Edición Volume 9 - 2022, 2022, ISSN 2296-9144
Editor: FRONTIERS
DOI: 10.3389/frobt.2022.926255

Establishing Imaging Biomarkers of Host Immune System Efficacy during Glioblastoma Therapy Response: Challenges, Obstacles and Future Perspectives

Autores: Ana Paula Candiota; Carles Arús
Publicado en: Metabolites, Edición (12)3, March 2022, 2022, Página(s) 243, ISSN 2218-1989
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/metabo12030243

Diffusion-weighted SPECIAL improves the detection of J-coupled metabolites at ultrahigh magnetic field

Autores: Jessie Mosso, Dunja Simicic, Bernard Lanz, Rolf Gruetter, Cristina Cudalbu
Publicado en: Magnetic Resonance in Medicine, 2023, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29805

Denoising single MR spectra by deep learning: Miracle or mirage?

Autores: Dziadosz M, Rizzo R, Kyathanahally SP, Kreis R.
Publicado en: Magnetic Resonance Medicine, 2023, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29762

Factorizer: A scalable interpretable approach to context modeling for medical image segmentation

Autores: Pooya Ashtari; Diana M. Sima; Lieven De Lathauwer; Dominique Sappey-Marinier; Frederik Maes; Sabine Van Huffel
Publicado en: Medical Image Analysis, Edición 84, 2023, ISSN 1361-8415
Editor: Elsevier BV
DOI: 10.1016/j.media.2022.102706

Proton metabolic mapping of the brain at 7 T using a two-dimensional free induction decay–echo-planar spectroscopic imaging readout with lipid suppression.

Autores: Nam KM, Hendriks AD, Boer VO, Klomp DWJ, Wijnen JP, Bhogal AA
Publicado en: NMR in Biomedicine, 2022, ISSN 0952-3480
Editor: John Wiley & Sons Inc.
DOI: 10.1002/nbm.4771

Developments in proton MR spectroscopic imaging of prostate cancer

Autores: Angeliki Stamatelatou; Tom W. J. Scheenen; Arend Heerschap
Publicado en: Magnetic Resonance Materials in Physics, Edición 35, 2022, ISSN 1352-8661
Editor: Springer
DOI: 10.1007/s10334-022-01011-9

High Angular Resolution Susceptibility Imaging and Estimation of Fiber Orientation Distribution Functions in Primate Brain

Autores: Dimitrios G. Gkotsoulias, Roland Müller, Carsten Jäger, Torsten Schlumm, Toralf Mildner, Cornelius Eichner, André Pampel, Jennifer Jaffe, Tobias Gräßle, Niklas Alsleben, Jingjia Chen, Catherine Crockford, Roman Wittig, Chunlei Liu, Harald E. Möller
Publicado en: NeuroImage, Edición Volume 276, 1 August 2023, 120202, 2023, ISSN 1053-8119
Editor: Academic Press
DOI: 10.1101/2022.10.23.513390

RF Coil Setup for 31P MRSI in Tongue Cancer in vivo at 7 T

Autores: Forner R, Nam K, de Koning KJ, van der Velden T, van der Kemp W, Raaijmakers Am Klomp DWJ
Publicado en: Frontiers in Neurology, Edición Volume 12 - 2021, 2021, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2021.695202

NIfTI-MRS: A standard data format for magnetic resonance spectroscopy

Autores: Clarke W, Mikkelsen M, Oeltzschner G, Bell TK, Shamaei A, Soher BJ, Emir U, Wilson W
Publicado en: Magnetic Resonance in Medicine, Edición Volume88, Edición6, 2022, Página(s) Pages 2358-2370, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29418

New multiple sclerosis lesion segmentation and detection using pre-activation U-Net

Autores: Pooya Ashtari; Berardino Barile; Sabine Van Huffel; Dominique Sappey-Marinier
Publicado en: Frontiers in Neuroscience, Edición Volume 16 - 2022, 2022, ISSN 1662-4548
Editor: Frontiers Research Foundation
DOI: 10.3389/fnins.2022.975862

Data Augmentation using Generative Adversarial Neural Networks of Brain Structural Connectivity in Multiple Sclerosis

Autores: Berardino Barile, Aldo Marzullo, Claudio Stamile, Françoise Durand-Dubief, Dominique Sappey-Marinier
Publicado en: Computer Methods and Programs in Biomedicine, 2021, ISSN 2666-9900
Editor: Elsevier
DOI: 10.1016/j.cmpb.2021.106113

Model-informed unsupervised deep learning approaches to frequency and phase correction of MRS signals

Autores: Shamaei A, Starcukova J, Pavlova I, Starcuk Z.
Publicado en: Magnetic Resonance in Medicine, 2022, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.29498

PET CMRglc mapping and 1H-MRS show altered glucose uptake and neurometabolic profiles in BDL rats

Autores: Mosso J, Yin T, Poitry-Yamate C, Simicic D, Lepore M, McLin VA, Braissant O, Cudalbu C, Lanz B.
Publicado en: Analytical Biochemistry, Edición Volume 647, 15 June 2022, 114606, 2022, ISSN 0003-2697
Editor: Academic Press
DOI: 10.1016/j.ab.2022.114606

Using Single-Voxel Magnetic Resonance Spectroscopy Data Acquired at 1.5T to Classify Multivoxel Data at 3T: A Proof-of-Concept Study

Autores: Ungan G, Pons-Escoda A, Ulinic D, Arús C, Vellido A, Julià-Sapé M.
Publicado en: Cancers 2023, Edición 15(14):3709, 2023, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15143709

Deep learning pipeline for quality filtering of MRSI spectra.

Autores: Rakić M, Turco F, Weng G, Maes F, Sima DM, Slotboom J.
Publicado en: NMR Biomedicine, Edición e5012, 2023, ISSN 1099-1492
Editor: John Wiley & Sons Inc.
DOI: 10.1002/nbm.5012

Physics-informed Deep Learning Approach to Quantification of Human Brain Metabolites from Magnetic Resonance Spectroscopy

Autores: Shamaei A, Starcukova J, Starcuk Z.
Publicado en: Computers in Biology and Medicine, Edición Volume 158, May 2023, 106837, 2023, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2023.106837

Conference proceedings (12)

Unsupervised Tensor Factorization for Classification of MS clinical Forms

Autores: Berardino Barile, Aldo Marzullo, Claudio Stamile, Françoise Durand-Dubief, Dominique Sappey-Marinier
Publicado en: 25th International Conference in Pattern Recognition - ICPR 2020, Edición 2020, 2020
Editor: ICPR 2020

Potential benefits from Multi-Echo Single-Shot Spectroscopy with a combined fitting process,

Autores: Rudy Rizzo, Roland Kreis
Publicado en: ISMRM 2020, Edición ISMRM 2020, 2020
Editor: ISMRM 2020

Accelerating CEST by 2D CAIPIRINHA: a simulation study on Z-spectra from 3D whole brain CEST-MRI

Autores: K. M. Nam, A. Hendriks, D. Klomp, E. Wiegers, J. Wijnen
Publicado en: ESMRMB 2019, 2019
Editor: ESMRMB 2019

Invisible receiver arrays? Proof of effective long distance RF arrays when tissue loss dominates

Autores: K. M. Nam, Cezar Alborahal, Kaizad Rustomji, Tryfon Antonakakis, Catalina Arteaga de Castro, Jannie P. Wijnen, and Dennis W.J. Klomp
Publicado en: ISMRM 2020, 2020, Página(s) Poster
Editor: ISMRM 2020

Low-Rank Convolutional Networks for Brain Tumor Segmentation 

Autores:  Ashtari P., Maes F., Van Huffel S., 
Publicado en: MICCAI BrainLes 2020, 2021
Editor: Springer
DOI: 10.1007/978-3-030-72084-1_42

Multimodal assessment of brain energy metabolism in a rat model of hepatic encephalopathy using 1H-MRS and 18F-FDG PET – a pilot study

Autores: Jessie Mosso, Carole Poitry-Yamate, Dunja Simicic, Mario Lepore, Cristina Cudalbu, and Bernard Lanz
Publicado en: ISMRM20, 2020
Editor: ISMRM20

Prediction of Multiple Sclerosis Disability using Machine Learning Ensemble of Boosting Methods based on structural brain connectivity

Autores: Berardino Barile, Aldo Marzullo, Claudio Stamile, Françoise Durand-Dubief, Dominique Sappey-Marinier
Publicado en: ESMRMB 2020, 2020
Editor: ESMRMB 2020

Brain structural connectivity data augmentation using Generative Adversarial Network

Autores: B. Barile, C. Stamile, A. Marzullo, F. Durand-Dubief, D. Sappey-Marinier
Publicado en: 37th Annual Scientific Meeting of ESMRMB, 2020
Editor: 37th Annual Scientific Meeting of ESMRMB

Enabling Fast Metabolic Mapping of the Brain using Lipid Crushing and an EPSI Readout at 7T

Autores: K. M. Nam, Arjan Hendriks, Vincent O. Boer, Dennis D.J. Klomp, Jannie P. Wijnen, and Alex Bhogal
Publicado en: ISMRM 2020, Edición 2020 yearly, 2020
Editor: ISMRM 2020

Relations between functional brain connectivity and intelligence using functional MRI and graphs techniques

Autores: V. Ghibaudo, A. Stadler, B. Barile, F. Nusbaum, S. Mouchet-Mages, D. Sappey-Marinier
Publicado en: 37th Annual Scientific Meeting of ESMRMB, 2020
Editor: ESMRMB

Silent EPSI using a gradient axis driven at 20 kHz

Autores: Edwin Versteeg, K.M. Nam, Dennis Klomp, Jeroen Hendrikse, Alex Bhogal, Jeroen Siero, and Jannie Wijnen
Publicado en: ISMRM 2020, Edición ISMRM 2020, 2020
Editor: ISMRM 2020

Deep Learning for Magnetic Resonance Spectroscopy Quantification: a Time-Frequency Analysis Approach

Autores: Shamaei, Amirmohammad
Publicado en: Proceedings of the 26th Student EEICT 2020, 2020, ISBN 978-80-214-5868-0
Editor: Brno University of Technology,

Thesis and dissertations (1)

Implementation of high-resolution MRSI methods in a pre-clinical scanner, and optimization for brain longitudinal studies of therapy response in mice glioma model.

Autores: Javed, Zoona
Publicado en: PhD Thesis in Electronic and Telecommunication Engineering, 2023
Editor: Universitat Autònoma de Barcelona