INnate-ImmunomeTabolIsm as Antiviral TargEt

Información del proyecto

INITIATE

Identificador del acuerdo de subvención: 813343

DOI

10.3030/813343

Proyecto cerrado

Fecha de la firma de la CE 21 Mayo 2019

Fecha de inicio 1 Mayo 2019

Fecha de finalización 30 Abril 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 054 106,16

Aportación de la UE

€ 4 054 106,16

Coordinado por

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (1)

Report on SD5: Publications

Report on publications of research results of WP 123 Drafts of at least 2 manuscripts per ESR

Publicaciones

Peer reviewed articles (22)

Proteomics approaches for the identification of protease substrates during virus infection

Autores: Xavier Martiáñez-Vendrell, Marjolein Kikkert
Publicado en: Advances in virus research, Edición 109, 2021, Página(s) 135-161, ISSN 0065-3527
Editor: Academic Press
DOI: 10.1016/bs.aivir.2021.03.003

Detection of Viral Infections by Innate Immunity

Autores: Michael Carty, Coralie Guy, Andrew G. Bowie
Publicado en: Biochemical Pharmacology, Edición 183, 2021, Página(s) 114316, ISSN 0006-2952
Editor: Elsevier BV
DOI: 10.1016/j.bcp.2020.114316

100 days of solitude: The spring of COVID-19 through the eyes of 15 young virologists of the INITIATE program

Autores: Zsofia Keszei, Xavier Martinez Vendrell, Maria Soultsioti, Pau Ribo Molina, Lorenz Wirth, Hauke Weiss, Magdalini Alexandridi, Chiara Aloise, Balasubramanian Susma, Coralie Guy, Adriana Loverre, Sonia Marquez Martinez, Julija Mazej, Alix Spahn, Mihai Sularea, John Hiscott, Bernadette van den Hoogen
Publicado en: Virus Research, Edición 287, 2020, Página(s) 198093, ISSN 0168-1702
Editor: Elsevier BV
DOI: 10.1016/j.virusres.2020.198093

Metabolite Transporters as Regulators of Immunity

Autores: Hauke J. Weiss, Stefano Angiari
Publicado en: Metabolites, Edición 10/10, 2020, Página(s) 418, ISSN 2218-1989
Editor: MDPI journals
DOI: 10.3390/metabo10100418

Bridging the gap - a new role for STAT3 in TLR4-mediated metabolic reprogramming

Autores: Hauke J Weiss, Luke Aj O''Neill
Publicado en: Immunology & Cell Biology, Edición 99(2), 2021, Página(s) 122-125, ISSN 0818-9641
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imcb.12414

Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN

Autores: Simon Loevenich, Alix S. Spahn, Kristin Rian, Victor Boyartchuk, Marit Walbye Anthonsen
Publicado en: Frontiers in Immunology, Edición 12, 2021, ISSN 1664-3224
Editor: Frontiers Media S.A
DOI: 10.3389/fimmu.2021.563336

Move and countermove: the integrated stress response in picorna- and coronavirus-infected cells

Autores: Chiara Aloise, Jelle G Shipper, Raoul J de Groot, Frank Jm van Kupperveld
Publicado en: Current Opinion in Immunology, Edición 79, 2022, Página(s) 102254, ISSN 0952-7915
Editor: Elsevier BV
DOI: 10.1016/j.coi.2022.102254

Of Flies and Men-The Discovery of TLRs

Autores: Hauke J Weiss, Luke AJ O'Neill
Publicado en: Cells, Edición 11(19), 2022, ISSN 0092-8674
Editor: Cell Press
DOI: 10.3390/cells11193127

Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver

Autores: Chiara Di Censo, Marie Marotel, Irene Mattiola, Lena Müller, Gianluca Scarno, Giuseppe Pietropaolo, Giovanna Peruzzi, Mattia Laffranchi, Julija Mazej, Mohamed Shaad Hasim, Sara Asif, Eleonora Russo, Luana Tomaipitinca, Helena Stabile, Seung-Hwan Lee, Laura Vian, Massimo Gadina, Angela Gismondi, Han-Yu Shih, Yohei Mikami, Cristina Capuano , Giovanni Bernardini, Michael Bonelli, Silvano Sozzani, An
Publicado en: European journal of immunology, Edición 51(11), 2021, Página(s) 2568-2575, ISSN 0014-2980
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202149209

Cell entry and innate sensing shape adaptive immune responses to adenovirus-based vaccines

Autores: Sonia Marquez-Martinez, Aneesh Vijayan, Selina Khan, Roland Zahn
Publicado en: Current opinion in immunology, Edición 80:102282, 2023, ISSN 0952-7915
Editor: Elsevier BV
DOI: 10.1016/j.coi.2023.102282

Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2

Autores: Alexandra Popa, Jakob-Wendelin Genger, Michael D Nicholson, Thomas Penz, Daniela Schmid, Stephan W Aberle, Benedikt Agerer, Alexander Lercher, Lukas Endler, Henrique Colaço, Mark Smyth, Michael Schuster, Miguel L Grau, Francisco Martínez-Jiménez, Oriol Pich, Wegene Borena, Erich Pawelka, Zsofia Keszei, Martin Senekowitsch, Jan Laine, Judith H Aberle, Monika Redlberger-Fritz, Mario Karolyi, Alex
Publicado en: Science translational medicine, Edición 12(573), 2020, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abe2555

Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication

Autores: Matteo Ferrari, Alessandra Zevini, Enrico Palermo, Michela Muscolini, Magdalini Alexandridi, Marilena P. Etna, Eliana M. Coccia, Ana Fernandez-Sesma, Carolyn Coyne, Donna D. Zhang, Ernesto T. A. Marques, David Olagnier, John Hiscott
Publicado en: Journal of Virology, Edición 94/24, 2020, ISSN 0022-538X
Editor: American Society for Microbiology
DOI: 10.1128/jvi.01551-20

Innate lymphoid cells type 2 and CD8+ T cells are perturbed in overweight and obese individuals with asthma.

Autores: Sophia Björkander, Paul Maier, Maura Kere, Simon Kebede Merid, Lorenz Wirth, Whitney Wiegel, Sandra Ekström, Inger Kull, Anna Bergström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt
Publicado en: Allergy, 2023, ISSN 0105-4538
Editor: Blackwell Publishing Inc.
DOI: 10.1111/all.15728

The global impact of the coronavirus pandemic

Autores: John Hiscott, Magdalini Alexandridi, Michela Muscolini, Evelyne Tassone, Enrico Palermo, Maria Soultsioti, Alessandra Zevini
Publicado en: Cytokine & Growth Factor Reviews, Edición 53, 2020, Página(s) 1-9, ISSN 1359-6101
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.cytogfr.2020.05.010

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression

Autores: Linda J. Visser, Chiara Aloise, Kirby N. Swatek, Gisselle N. Medina, Karin M. Olek, Huib H. Rabouw, Raoul J. de Groot, Martijn A. Langereis, Teresa de los Santos, David Komander, Tim Skern, Frank J. M. van Kuppeveld
Publicado en: PLOS Pathogens, Edición 16/7, 2020, Página(s) e1008702, ISSN 1553-7374
Editor: PLOS
DOI: 10.1371/journal.ppat.1008702

Inhibition of Glycolysis Impairs Retinoic Acid-Inducible Gene I-Mediated Antiviral Responses in Primary Human Dendritic Cells

Autores: Alessandra Zevini, Enrico Palermo, Daniele Di Carlo, Magdalini Alexandridi, Serena Rinaldo, Alessio Paone, Francesca Cutruzzola, Marilena P Etna, Eliana M Coccia, David Olagnier, John Hiscott
Publicado en: Frontiers in cellular and infection microbiology, Edición 12:910864, 2022, ISSN 2235-2988
Editor: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.910864

Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale

Autores: Fabian Amman, Rudolf Markt, Lukas Endler, Sebastian Hupfauf, Benedikt Agerer, Anna Schedl, Lukas Richter, Melanie Zechmeister, Martin Bicher, Georg Heiler, Petr Triska, Matthew Thornton, Thomas Penz, Martin Senekowitsch, Jan Laine, Zsofia Keszei, Peter Klimek, Fabiana Nägele, Markus Mayr, Beatrice Daleiden, Martin Steinlechner, Harald Niederstätter, Petra Heidinger, Wolfgang Rauch, Christoph Sch
Publicado en: Nature Biotechnology, Edición 40(12), 2022, Página(s) 1814-1822, ISSN 1087-0156
Editor: Nature Publishing Group
DOI: 10.1038/s41587-022-01387-y

Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network

Autores: Bernadette van den Hoogen, Angela Santoni, Giuseppe Sciumé, Andrew Bowie, Cliona O’Farrelly, Luke O’Neill, Marit Anthonsen, Katerina Pardali, Simon Young, Andreas Bergthaler, Nicolas Manel, Roland Zahn, Marjolein Kikkert, Eric Snijder, Frank van Kuppeveld, Ron Fouchier, John Hiscott
Publicado en: Virus Research, Edición 287, 2020, Página(s) 198094, ISSN 0168-1702
Editor: Elsevier BV
DOI: 10.1016/j.virusres.2020.198094

The Coronavirus pandemic - 2022: Viruses, variants & vaccines.

Autores: Magdalini Alexandridi, Julija Mazej, Enrico Palermo, John Hiscott
Publicado en: Cytokine & Growth Factor Reviews, Edición 63, 2022, Página(s) 1-9, ISSN 1359-6101
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.cytogfr.2022.02.002

Virus-like particle - mediated delivery of the RIG-I agonist M8 induces a type I interferon response and protects cells against viral infection

Autores: Enrico Palermo, Magdalini Alexandridi, Daniele Di Carlo, Michela Muscolini, John Hiscott
Publicado en: Frontiers in cellular and infection microbiology, Edición 12:1079926, 2022, ISSN 2235-2988
Editor: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.1079926

Recent insights into innate immune nucleic acid sensing during viral infection.

Autores: Coralie Guy, Andrew G Bowie
Publicado en: Current Opinion in Immunology, Edición 78, 2022, ISSN 0952-7915
Editor: Elsevier BV
DOI: 10.1016/j.coi.2022.102250

Proteolytic Activities of Enterovirus 2A Do Not Depend on Its Interaction with SETD3

Autores: Xiaoyao Yang, Chiara Aloise, Arno L. W. van Vliet, Marleen Zwaagstra, Heyrhyoung Lyoo, Anchun Cheng, Frank J. M. van Kuppeveld
Publicado en: Viruses, Edición 14(7), 2022, Página(s) 1360, ISSN 1999-4915
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v14071360