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Active Pharmaceutical Production in Flow

Description du projet

Un programme de formation dédié à la recherche dans la production de la chimie de flux

La production de produits pharmaceutiques et de produits chimiques fins recourt à des opérations par lots, étant donné que de nombreuses synthèses efficaces nécessitent des réactifs et des conditions qu’il est trop dangereux de mettre à l’échelle. L’approche de manière continue des opérations favorise l’utilisation de plus petits réacteurs à une échelle industrielle, réduisant ainsi les risques liés aux conditions dangereuses. Financé par le programme Actions Marie Skłodowska-Curie, le projet APPFlow entend développer des processus plus efficaces et plus sûrs pour la production de produits chimiques. L’objectif consiste à utiliser une plateforme de recherche innovante pour la formation de chercheurs en début de carrière dans le domaine de la chimie de flux exploitée dans les industries des produits pharmaceutiques et des produits chimiques fins. Ces chercheurs travailleront dans des laboratoires universitaires et industriels afin d’acquérir une expérience et une formation uniques.

Objectif

APPFlow will develop Early Stage Researchers (ESRs) in innovative research through a focussed training plan centred on flow chemistry, essential for the pharmaceutical and fine chemical industries in Europe. The training programme and research proposed in APPFlow tackles the problems associated with the production of advanced intermediates en-route to Active Pharmaceutical Ingredients (APIs) in the pharma-industry. The proposal is aligned with important European research goals outlined in Horizon 2020. Specifically, this research will address areas related to Resource Efficiency, Health, Environment and Nanotechnology. The end goals align with those of the SPIRE 2030 targets and aims, most closely aligned with the goal of ‘a reduction of up to 20% in non-renewable, primary raw material intensity compared to current levels by 2030.’ It comprises of three training sites located in Ireland (1) and the UK (2) and involves multidisciplinary collaboration between academic and industrial partners, each with complementary expertise across a range of disciplines. The programme will train 3 ESRs who will gain state-of-the-art, transferable knowledge in a number of valuable areas such as organic chemistry, catalytic chemistry, chemical engineering, process design and economics. APPFlow will establish long-term collaborations and develop structured research and training relevant to industry and academia and result in highly trained and employable ESRs. At the end of the APPFlow programme, the ESRs will possess a multidimensional perspective to research, enabling them to address problems with a holistic approach. The ESRs will also develop a range of transferable “soft” managerial skills that will widen their potential career opportunities and ability to contribute to a range of different sectors. For example, they will receive business and entrepreneurship mentoring, which will assist them in becoming future business leaders.

Coordinateur

THE QUEEN'S UNIVERSITY OF BELFAST
Contribution nette de l'UE
€ 909 517,68
Adresse
UNIVERSITY ROAD LANYON BUILDING
BT7 1NN Belfast
Royaume-Uni

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Région
Northern Ireland Northern Ireland Belfast
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 909 517,68

Participants (1)

Partenaires (1)