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Active Pharmaceutical Production in Flow

Descrizione del progetto

Programma di formazione alla ricerca sulla produzione di chimica a flusso

La produzione di prodotti farmaceutici e di chimica fine impiega operazioni in serie, poiché molte operazioni di sintesi efficienti richiedono reagenti e condizioni troppo pericolose per un impiego su vasta scala. L’approccio al funzionamento continuo consente di usare reattori più piccoli su scala industriale, riducendo al minimo i rischi associati a condizioni pericolose. Il progetto APPFlow, finanziato dal programma di azioni Marie Skłodowska-Curie, si propone di sviluppare processi per la produzione di sostanze chimiche più efficienti e sicuri. L’obiettivo è quello di utilizzare una piattaforma di ricerca innovativa per la formazione di ricercatori all’inizio della carriera nel campo della chimica a flusso applicata all’industria farmaceutica e a quella della chimica fine. Questi ricercatori lavoreranno in laboratori sia accademici che industriali, acquisendo una gamma unica di esperienze e formazione.

Obiettivo

APPFlow will develop Early Stage Researchers (ESRs) in innovative research through a focussed training plan centred on flow chemistry, essential for the pharmaceutical and fine chemical industries in Europe. The training programme and research proposed in APPFlow tackles the problems associated with the production of advanced intermediates en-route to Active Pharmaceutical Ingredients (APIs) in the pharma-industry. The proposal is aligned with important European research goals outlined in Horizon 2020. Specifically, this research will address areas related to Resource Efficiency, Health, Environment and Nanotechnology. The end goals align with those of the SPIRE 2030 targets and aims, most closely aligned with the goal of ‘a reduction of up to 20% in non-renewable, primary raw material intensity compared to current levels by 2030.’ It comprises of three training sites located in Ireland (1) and the UK (2) and involves multidisciplinary collaboration between academic and industrial partners, each with complementary expertise across a range of disciplines. The programme will train 3 ESRs who will gain state-of-the-art, transferable knowledge in a number of valuable areas such as organic chemistry, catalytic chemistry, chemical engineering, process design and economics. APPFlow will establish long-term collaborations and develop structured research and training relevant to industry and academia and result in highly trained and employable ESRs. At the end of the APPFlow programme, the ESRs will possess a multidimensional perspective to research, enabling them to address problems with a holistic approach. The ESRs will also develop a range of transferable “soft” managerial skills that will widen their potential career opportunities and ability to contribute to a range of different sectors. For example, they will receive business and entrepreneurship mentoring, which will assist them in becoming future business leaders.

Coordinatore

THE QUEEN'S UNIVERSITY OF BELFAST
Contribution nette de l'UE
€ 909 517,68
Indirizzo
UNIVERSITY ROAD LANYON BUILDING
BT7 1NN Belfast
Regno Unito

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Regione
Northern Ireland Northern Ireland Belfast
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
€ 909 517,68

Partecipanti (1)

Partner (1)