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European Industrial Doctorate for enhancing upstream biopharmaceutical manufacturing process development through single cell analysis

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Publications

Proof-of-Concept of Continuous Transfection for Adeno-Associated Virus Production in Microcarrier-Based Culture

Author(s): Brian Ladd, Kevin Bowes, Mats Lundgren, Torbjörn Gräslund and Veronique Chotteau
Published in: Processes, 2022, 10(3), 515, 2022, ISSN 2227-9717
Publisher: MDPI
DOI: 10.3390/pr10030515

Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells

Author(s): Ioanna Tzani, Craig Monger, Krishna Motheramgari, Clair Gallagher, Ryan Hagan, Paul Kelly, Alan Costello, Justine Meiller, Patrick Floris, Lin Zhang, Martin Clynes, Jonathan Bones, Niall Barron, Colin Clarke
Published in: Biotechnology and Bioengineering, 117/8, 2020, Page(s) 2489-2503, ISSN 0006-3592
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27365

Tracing production instability in a clonally derived CHO cell line using single‐cell transcriptomics

Author(s): Ioanna Tzani, Nicolas Herrmann, Sara Carillo, Cathy A. Spargo, Ryan Hagan, Niall Barron, Jonathan Bones, W. Shannon Dillmore, Colin Clarke
Published in: Biotechnology and Bioengineering, 2021, ISSN 0006-3592
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27715