Training on Advanced Stem Cell Technologies in Neurology

Deliverables

Final program for research school on Bridging science, policy and society

EBC will have the definitive program for the Bridging science, policy and society research school including all appropriate details. A first indicative draft was already included in the proposal.

Report on scientific publications, exploitation and patenting activities.

EBC will prepare a report on all scientific publications exploitation and patenting activities that the ESRs will have generated along the project

Project logo and templates

All PI will agree with the logo that represent the project and templates for power point presentations will be distributed.

Final program for research school on Reprogramming and Molecular Biotechnology

OSR and KI will have the definitive program for the Reprogramming and Molecular Biotechnology research school including all appropriate details. A first indicative draft was already included in the proposal.

Final program for research school on Technology Transfer

CU Cairn and Plasticell will have the definitive program with for the Technology Transfer research school including all appropriate details A first indicative draft was already included in the proposal

Final program for research school on Biotechnology for cell culture

UB and IBEC will have the definitive program for the Biotechnology for cell culture research school including all appropriate details. A first indicative draft was already included in the proposal.

Report on public engagement activities by ESRs

EBC will prepare a report about all the activities undertaken by the ESRs all over the project to disseminate the different results to the public The report will discuss the achievements and deviations occurred from the Public Engagement plans see D53

Publish ASCTN-Training website

The communication and exploitation coordinator (CEC) will have developed the web site for ASCTN-Training and will have published it.

Publications

Hyaluronic acid-based bioink improves the differentiation and network formation of neural progenitor cells

Author(s): Inês Pereira, Maria José López Martínez, Aranzazu Villasante, Clelia Introna, Daniel Tornero, Josep M. Canals and Josep Samitier
Published in: Frontiers in Bioengineering and Biotechnology, Issue 11, 2023, ISSN 2296-4185
Publisher: Frontiers Media S.A.
DOI: 10.3389/fbioe.2023.1110547

Cytotoxicity Assessment of Surface-Modified Magnesium Hydroxide Nanoparticles

Author(s): Mónica Echeverry-Rendón, Brina Stančič, Kirsten Muizer, Valentina Duque, Deanne Jennei Calderon, Felix Echeverria, and Martin C. Harmsen
Published in: ACS Omega, Issue 7 (21), 2022, Page(s) 17528–17537, ISSN 2470-1343
Publisher: American Chemical Society
DOI: 10.1021/acsomega.1c06515

Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates

Author(s): Sánchez-González C, Herrero Martín JC, Salegi Ansa B, Núñez de Arenas C, Stančič B, Pereira MP, Contreras L, Cuezva JM, Formentini L
Published in: Cell Death & Disease, Issue 13 (561), 2022, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/s41419-022-05016-z

Adult-born neurons promote cognitive flexibility by improving memory precision and indexing

Author(s): Gabriel Berdugo-Vega, Chi-Chieh Lee, Alexander Garthe, Gerd Kempermann, Federico Calegari
Published in: Hippocampus (Online)., Issue 31 (10), 2021, Page(s) 1068-1079, ISSN 1098-1063
Publisher: Wiley Periodicals, LLC
DOI: 10.1002/hipo.23373

A reference induced pluripotent stem cell line for large-scale collaborative studies

Author(s): Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, Santiana M, Faghri F, Nalls MA, Vitale D, Ballard S, Qi YA, Ramos DM, Anderson KM, Stadler J, Narayan P, Papademetriou J, Reilly L, Nelson MP, Aggarwal S, Rosen LU, Kirwan P, Pisupati V, Coon SL, Scholz
Published in: Cell Stem Cell, Issue Dec 1;29(12), 2022, Page(s) 1685-1702.e22., ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2022.11.004

Single cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation

Author(s): Nishimura K, Yang S, Lee KW, Ásgrímsdóttir ES, Nikouei K, Paslawski W, Gnodde S, Lyu G, Hu L, Saltó C, Svenningsson P, Hjerling-Leffler J, Linnarsson S, Arenas E.
Published in: Stem Cell Reports, Issue Nov 8:S2213-6711(22), 2022, Page(s) 00512-4., ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2022.10.016

Standardization of cell culture conditions and routine genomic screening under a quality management system lead to reduced genomic instability in hPSCs

Author(s): Francisco J Molina-Ruiz,, Clelia Introna , Georgina Bombau, Mireia Galofre, Josep M Canals
Published in: Cells, Issue 11 (13), 2022, Page(s) 1984, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11131984

A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development

Author(s): Valerio Benedetti, Federica Banfi, Mattia Zaghi, Raquell Moll-Diaz, Luca Massimino, Laura Argelich, Edoardo Bellini, Simone Bido, Sharon Muggeo, Gabriele Ordazzo, Giuseppina Mastrototaro, Matteo Moneta, Alessandro Sessa, Vania Broccoli
Published in: Science Advances, Issue 8 (31), 2022, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn3986

Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life

Author(s): Gabriel Berdugo-Vega, Gonzalo Arias-Gil, Adrian López-Fernández, Benedetta Artegiani, Joanna M. Wasielewska, Chi-Chieh Lee, Michael T. Lippert, Gerd Kempermann, Kentaroh Takagaki, Federico Calegari
Published in: Nature Communications, Issue 11/1, 2020, Page(s) 1-12, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-14026-z

The blood endothelial cell chamber - An innovative system to study immune responses in drug development.

Author(s): Stančič B, Qvarfordt B, Berglund MM, Brenden N, Sydow Bäckman M, Fransson M, Nordling S, Magnusson PU
Published in: International Immunopharmacology, Issue 90 (2021) 107237, 2022, ISSN 1567-5769
Publisher: Elsevier BV
DOI: 10.1016/j.intimp.2020.107237

Is the Immunological Response a Bottleneck for Cell Therapy in Neurodegenerative Diseases?

Author(s): Cristina Salado-Manzano, Unai Perpiña, Marco Straccia, Francisco J. Molina-Ruiz, Emanuele Cozzi, Anne E. Rosser, Josep M. Canals
Published in: Frontiers in Cellular Neuroscience, Issue 14, 2020, Page(s) 1-33, ISSN 1662-5102
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncel.2020.00250

Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition

Author(s): Mattia Zaghi , Federica Banfi, Luca Massimino, Monica Volpin, Edoardo Bellin, Simone Brusco, Ivan Merelli, Cristiana Barone, Michela Bruni, Linda Bossini, Luigi Antonio Lamparelli, Laura Pintado, Deborah D’Aliberti, Silvia Spinelli, Luca Mologni, Gaia Colasante, Federica Ungaro, Jean-Michel Cioni, Emanuele Azzoni, Rocco Piazza, Eugenio Montini, Vania Broccoli, and Alessandro Sessa
Published in: BioRxiv – The preprint server for Biology, 2022, ISSN 2692-8205
Publisher: BioRxiv – The preprint server for Biology
DOI: 10.1101/2022.09.12.507599

Challenges in progressing cell therapies to the clinic for Huntington's disease: A review of the progress made with pluripotent stem cell derived medium spiny neurons

Author(s): Garcia Jareño P, Bartley OJM, Precious SV, Rosser AE, Lelos MJ.
Published in: International Review of Neurobiology, Issue 166 (chapter one), 2022, Page(s) 1-48, ISSN 0074-7742
Publisher: Academic Press Inc.
DOI: 10.1016/bs.irn.2022.09.003

Deliverables

Publications

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