Training on Advanced Stem Cell Technologies in Neurology

Livrables

Final program for research school on Bridging science, policy and society

EBC will have the definitive program for the Bridging science, policy and society research school including all appropriate details. A first indicative draft was already included in the proposal.

Report on scientific publications, exploitation and patenting activities.

EBC will prepare a report on all scientific publications exploitation and patenting activities that the ESRs will have generated along the project

Project logo and templates

All PI will agree with the logo that represent the project and templates for power point presentations will be distributed.

Final program for research school on Reprogramming and Molecular Biotechnology

OSR and KI will have the definitive program for the Reprogramming and Molecular Biotechnology research school including all appropriate details. A first indicative draft was already included in the proposal.

Final program for research school on Technology Transfer

CU Cairn and Plasticell will have the definitive program with for the Technology Transfer research school including all appropriate details A first indicative draft was already included in the proposal

Final program for research school on Biotechnology for cell culture

UB and IBEC will have the definitive program for the Biotechnology for cell culture research school including all appropriate details. A first indicative draft was already included in the proposal.

Report on public engagement activities by ESRs

EBC will prepare a report about all the activities undertaken by the ESRs all over the project to disseminate the different results to the public The report will discuss the achievements and deviations occurred from the Public Engagement plans see D53

Publish ASCTN-Training website

The communication and exploitation coordinator (CEC) will have developed the web site for ASCTN-Training and will have published it.

Publications

Hyaluronic acid-based bioink improves the differentiation and network formation of neural progenitor cells

Auteurs: Inês Pereira, Maria José López Martínez, Aranzazu Villasante, Clelia Introna, Daniel Tornero, Josep M. Canals and Josep Samitier
Publié dans: Frontiers in Bioengineering and Biotechnology, Numéro 11, 2023, ISSN 2296-4185
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fbioe.2023.1110547

Cytotoxicity Assessment of Surface-Modified Magnesium Hydroxide Nanoparticles

Auteurs: Mónica Echeverry-Rendón, Brina Stančič, Kirsten Muizer, Valentina Duque, Deanne Jennei Calderon, Felix Echeverria, and Martin C. Harmsen
Publié dans: ACS Omega, Numéro 7 (21), 2022, Page(s) 17528–17537, ISSN 2470-1343
Éditeur: American Chemical Society
DOI: 10.1021/acsomega.1c06515

Chronic inhibition of the mitochondrial ATP synthase in skeletal muscle triggers sarcoplasmic reticulum distress and tubular aggregates

Auteurs: Sánchez-González C, Herrero Martín JC, Salegi Ansa B, Núñez de Arenas C, Stančič B, Pereira MP, Contreras L, Cuezva JM, Formentini L
Publié dans: Cell Death & Disease, Numéro 13 (561), 2022, ISSN 2041-4889
Éditeur: Nature Publishing Group
DOI: 10.1038/s41419-022-05016-z

Adult-born neurons promote cognitive flexibility by improving memory precision and indexing

Auteurs: Gabriel Berdugo-Vega, Chi-Chieh Lee, Alexander Garthe, Gerd Kempermann, Federico Calegari
Publié dans: Hippocampus (Online)., Numéro 31 (10), 2021, Page(s) 1068-1079, ISSN 1098-1063
Éditeur: Wiley Periodicals, LLC
DOI: 10.1002/hipo.23373

A reference induced pluripotent stem cell line for large-scale collaborative studies

Auteurs: Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, Santiana M, Faghri F, Nalls MA, Vitale D, Ballard S, Qi YA, Ramos DM, Anderson KM, Stadler J, Narayan P, Papademetriou J, Reilly L, Nelson MP, Aggarwal S, Rosen LU, Kirwan P, Pisupati V, Coon SL, Scholz
Publié dans: Cell Stem Cell, Numéro Dec 1;29(12), 2022, Page(s) 1685-1702.e22., ISSN 1934-5909
Éditeur: Cell Press
DOI: 10.1016/j.stem.2022.11.004

Single cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation

Auteurs: Nishimura K, Yang S, Lee KW, Ásgrímsdóttir ES, Nikouei K, Paslawski W, Gnodde S, Lyu G, Hu L, Saltó C, Svenningsson P, Hjerling-Leffler J, Linnarsson S, Arenas E.
Publié dans: Stem Cell Reports, Numéro Nov 8:S2213-6711(22), 2022, Page(s) 00512-4., ISSN 1934-5909
Éditeur: Cell Press
DOI: 10.1016/j.stemcr.2022.10.016

Standardization of cell culture conditions and routine genomic screening under a quality management system lead to reduced genomic instability in hPSCs

Auteurs: Francisco J Molina-Ruiz,, Clelia Introna , Georgina Bombau, Mireia Galofre, Josep M Canals
Publié dans: Cells, Numéro 11 (13), 2022, Page(s) 1984, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells11131984

A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development

Auteurs: Valerio Benedetti, Federica Banfi, Mattia Zaghi, Raquell Moll-Diaz, Luca Massimino, Laura Argelich, Edoardo Bellini, Simone Bido, Sharon Muggeo, Gabriele Ordazzo, Giuseppina Mastrototaro, Matteo Moneta, Alessandro Sessa, Vania Broccoli
Publié dans: Science Advances, Numéro 8 (31), 2022, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn3986

Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life

Auteurs: Gabriel Berdugo-Vega, Gonzalo Arias-Gil, Adrian López-Fernández, Benedetta Artegiani, Joanna M. Wasielewska, Chi-Chieh Lee, Michael T. Lippert, Gerd Kempermann, Kentaroh Takagaki, Federico Calegari
Publié dans: Nature Communications, Numéro 11/1, 2020, Page(s) 1-12, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-019-14026-z

The blood endothelial cell chamber - An innovative system to study immune responses in drug development.

Auteurs: Stančič B, Qvarfordt B, Berglund MM, Brenden N, Sydow Bäckman M, Fransson M, Nordling S, Magnusson PU
Publié dans: International Immunopharmacology, Numéro 90 (2021) 107237, 2022, ISSN 1567-5769
Éditeur: Elsevier BV
DOI: 10.1016/j.intimp.2020.107237

Is the Immunological Response a Bottleneck for Cell Therapy in Neurodegenerative Diseases?

Auteurs: Cristina Salado-Manzano, Unai Perpiña, Marco Straccia, Francisco J. Molina-Ruiz, Emanuele Cozzi, Anne E. Rosser, Josep M. Canals
Publié dans: Frontiers in Cellular Neuroscience, Numéro 14, 2020, Page(s) 1-33, ISSN 1662-5102
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fncel.2020.00250

Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition

Auteurs: Mattia Zaghi , Federica Banfi, Luca Massimino, Monica Volpin, Edoardo Bellin, Simone Brusco, Ivan Merelli, Cristiana Barone, Michela Bruni, Linda Bossini, Luigi Antonio Lamparelli, Laura Pintado, Deborah D’Aliberti, Silvia Spinelli, Luca Mologni, Gaia Colasante, Federica Ungaro, Jean-Michel Cioni, Emanuele Azzoni, Rocco Piazza, Eugenio Montini, Vania Broccoli, and Alessandro Sessa
Publié dans: BioRxiv – The preprint server for Biology, 2022, ISSN 2692-8205
Éditeur: BioRxiv – The preprint server for Biology
DOI: 10.1101/2022.09.12.507599

Challenges in progressing cell therapies to the clinic for Huntington's disease: A review of the progress made with pluripotent stem cell derived medium spiny neurons

Auteurs: Garcia Jareño P, Bartley OJM, Precious SV, Rosser AE, Lelos MJ.
Publié dans: International Review of Neurobiology, Numéro 166 (chapter one), 2022, Page(s) 1-48, ISSN 0074-7742
Éditeur: Academic Press Inc.
DOI: 10.1016/bs.irn.2022.09.003

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