Research and Training in Early Life Nutrition to Prevent Disease

Project Information

GROWTH

Grant agreement ID: 814168

DOI

10.3030/814168

Project closed

EC signature date 31 July 2018

Start date 1 June 2019

End date 30 April 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 2 133 077,52

EU contribution

€ 2 133 077,52

Coordinated by

DSCN RESEARCH B.V.
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (4)

Signaling molecules associated with response to FMT

Bacterial composition in responding and non-responding UC patients and an inventory of microbial and metabolic signaling molecules associated with response to FMT.

GROWTH training certificates
Awarding of doctoral degrees
Report molecular pathways in anastomotic healing and leakage

The mechanisms of colorectal anastomotic healing (CAH) will be analysed by using a newly generated and validated mouse model. Longitudinal gene expression profiling of muscularis and lamina propria mucosae tissue after surgery will be performed to understand underlying healing pathways in timely manner.

Documents, reports (1)

Peer commentary

Journal Club result: ‘Peer Commentary’ (M42).

Websites, patent fillings, videos etc. (2)

GROWTH public website

First version of the GROWTH public website, including a job application portal.

Educational videos showing layman presentations

Educational videos showing layman presentations for each WP.

Open Research Data Pilot (1)

Initial data management plan

Publications

Peer reviewed articles (7)

Duration of Neonatal Antibiotic Exposure in Preterm Infants in Association with Health and Developmental Outcomes in Early Childhood

Author(s): Nancy Deianova, Conceptualization, Methodology, Formal analysis, Investigation, Data curation, Writing – original draft, Writing – review & editing, Visualization, Project administration,1,2,3,* Nanne K. de Boer,4 Hafsa Aoulad Ahajan, Investigation, Data curation, Writing – review & editing,1 Cilla Verbeek, Investigation, Data curation, Writing – review & editing,1 Cornelieke S. H. Aarnoud
Published in: Antibiotics, Issue 12(6):, 2023, Page(s) 967, ISSN 2079-6382
Publisher: MDPI
DOI: 10.3390/antibiotics12060967

Time to first passage of meconium and defecation frequency preceding necrotizing enterocolitis in preterm infants: a case–control study

Author(s): Nancy Deianova,corresponding author1,2 Quincy Moonen,1 Sientje E. Sluis,1 Hendrik J. Niemarkt,3 Wouter J. de Jonge,4 Marc A. Benninga,1 Nanne K. H. de Boer,5 Helen L. Tanger,6,7 Mirjam M. van Weissenbruch,7 Anton H. van Kaam,7 Tim G. J. de Meij,1,2 and Ilan J. N. Koppen1
Published in: European Journal of Pediatrics, Issue 182(9):, 2023, Page(s) 3907–3915, ISSN 1432-1076
Publisher: Springerlink
DOI: 10.1007/s00431-023-05035-8

Exploring the Immunomodulatory Potential of Human Milk: Aryl Hydrocarbon Receptor Activation and Its Impact on Neonatal Gut Health

Author(s): Wieser, N.V.; Ghiboub, M.; Verseijden, C.; van Goudoever, J.B.; Schoonderwoerd, A.; de Meij, T.G.J.; Niemarkt, H.J.; Davids, M.; Lefèvre, A.; Emond, P.; et a
Published in: Nutrients, Issue 16,, 2024, Page(s) 1531, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu16101531

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study

Author(s): Nancy Deianova, Sofia el Manouni el Hassani, Hendrik J. Niemarkt, Veerle Cossey, Anton H. van Kaam, Floor Jenken, Mirjam M. van Weissenbruch, Esmee M. Doedes, Kyra Baelde, Renee Menezes, Marc A. Benninga, Wouter J. de Jonge, Nanne K. de Boer, Tim G. de Meij
Published in: Biosensors, Issue 10/5, 2020, Page(s) 50, ISSN 2079-6374
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios10050050

Fecal amine metabolite analysis before onset of severe necrotizing enterocolitis in preterm infants: a prospective case-control study

Author(s): N Deianova 1 , S El Manouni El Hassani 2 , E A Struijs 3 , E E W Jansen 3 , A Bakkali 3 , M A van de Wiel 4 , W P de Boode 5 , C V Hulzebos 6 , A H van Kaam 7 , B W Kramer 8 , E d'Haens 9 , D C Vijlbrief 10 , M M van Weissenbruch 7 , W J de Jonge 11 , M A Benninga 12 , H J Niemarkt 13 , N K H de Boer 14 , T G J de Meij 2
Published in: Sci Rep ., Issue Jul 19;12(1), 2022, Page(s) 12310, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-16351-8

Association between duration of early empiric antibiotics and necrotizing enterocolitis and late-onset sepsis in preterm infants: a multicenter cohort study

Author(s): "Thomas H. Dierikx,corresponding author#1,2 Nancy Deianova,#1,2 Jip Groen,1,2 Daniel C. Vijlbrief,3 Christian Hulzebos,4 Willem P. de Boode,5 Esther J. d’Haens,6 Veerle Cossey,7 Boris W. Kramer,8 Mirjam M. van Weissenbruch,9,10 Wouter J. de Jonge,11 Marc A. Benninga,2,12 Chris H. van den Akker,9,10 Anton H. van Kaam,9,10 Nanne K. H. de Boer,2,13 Douwe H. Visser,9,10 Hendrik J. Niemarkt,14 and Tim"
Published in: European Journal Pediatrics, Issue 181(10), 2022, Page(s) 3715–3724, ISSN 1432-1076
Publisher: SpringerLink
DOI: 10.1007/s00431-022-04579-5

Fecal Volatile Metabolomics Predict Gram-Negative Late-Onset Sepsis in Preterm Infants: A Nationwide Case-Control Study

Author(s): Nina M Frerichs 1 , Sofia El Manouni El Hassani 1 , Nancy Deianova 1 , Mirjam M van Weissenbruch 2 , Anton H van Kaam 2 , Daniel C Vijlbrief 3 , Johannes B van Goudoever 1 , Christian V Hulzebos 4 , Boris W Kramer 5 , Esther J d'Haens 6 , Veerle Cossey 7 , Willem P de Boode 8 , Wouter J de Jonge 9 , Alfian N Wicaksono 10 , James A Covington 10 , Marc A Benninga 1 , Nanne K H de Boe
Published in: Microorganisms, Issue 11(3):, 2023, Page(s) 572, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms11030572

Conference proceedings (1)

A prospective pilot study of desorption electrospray ionisation mass spectrometry (DESI-MS) for the early detection of colorectal adenoma

Author(s): Maria Sani; Lauren Ford; Daniel Simon; Yuchen Xiang; James McKenzie; Stefania Manetta Stavrakaki; Petra Paizs; Tausif Huq; Jim Higginson; James Alexander; Zoltan Takats; James Kinross
Published in: Cancer Research, Issue Cancer Res (2022) 82 (12_Supplement): 3905., 2022, Page(s) 82, ISSN 0973-1482
Publisher: AACR
DOI: 10.1158/1538-7445.am2022-3905