A European Training Network to Combat Bone Pain

Livrables

BonePainII website up and running

Functioning

Presentations of key talks at network meetings posted online

Presentations posted on webpage and You Tube

BonePainII website

Updated regularly at least every four months

All ESRs recruited

Recruitment completed all ESRs enrolled in a PhD

Pain Mechanisms and Therapeutics Conference, and 2022

Talks submitted to the pain conferences in Sicily in June 2020 and 2022

Publications

Developments in Understanding Diffuse Noxious Inhibitory Controls: Pharmacological Evidence from Pre-Clinical Research

Auteurs: Mateusz Wojciech Kucharczyk, Diego Valiente, Kirsty Bannister
Publié dans: Journal of Pain Research, 2021, ISSN 1178-7090
Éditeur: Dove Medical Press Limited
DOI: 10.2147/jpr.s258602

A multimodal 3D neuro-microphysiological system with neurite-trapping microelectrodes

Auteurs: Beatriz Molina-Martínez, Laura-Victoria Jentsch, Fulya Ersoy, Matthijs van der Moolen, Stella Donato, Torbjørn V Ness, Peter Heutink, Peter D Jones, Paolo Cesare
Publié dans: Biofabrication, 2022, ISSN 1758-5082
Éditeur: IOS Press
DOI: 10.1088/1758-5090/ac463b

Systematic review and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain

Auteurs: Soliman, Nadia Haroutounian, Simon Hohmann, Andrea G. Krane, Elliot Liao, Jing Macleod, Malcolm Segelcke, Daniel Sena, Christopher Thomas, James Vollert, Jan Wever, Kimberley Alaverdyan, Harutyun Barakat, Ahmed Barthlow, Tyler Bozer, Amber L. Harris Davidson, Alexander Diaz-delCastillo, Marta Dolgorukova, Antonina Ferdousi, Mehnaz I. Healy, Catherine Hong, Simon Hopkins, Mary James, Arul Leake, Ha
Publié dans: Pain, 2021, ISSN 0304-3959
Éditeur: Elsevier BV
DOI: 10.1097/j.pain.0000000000002269

Transcriptome sequencing identifies a noncoding, deep intronic variant in CLCN7 causing autosomal recessive osteopetrosis

Auteurs: Odelia Chorin, Naomi Yachelevich, Khaled Mohamed, Ilana Moscatelli, John Pappas, Kim Henriksen, Gilad D. Evrony
Publié dans: Molecular Genetics & Genomic Medicine, Numéro 8/10, 2020, ISSN 2324-9269
Éditeur: Wiley
DOI: 10.1002/mgg3.1405

What Did We Learn About Fracture Pain from Animal Models?

Auteurs: Andreea Radulescu, Fletcher A White, Chantal Chenu
Publié dans: Journal of Pain Research, 2022, Page(s) 2845-2856, ISSN 1178-7090
Éditeur: Dove Medical Press Limited
DOI: 10.2147/jpr.s361826

3D micro-organisation printing of mammalian cells to generate biological tissues

Auteurs: Gavin D. M. Jeffries, Shijun Xu, Tatsiana Lobovkina, Vladimir Kirejev, Florian Tusseau, Christoffer Gyllensten, Avadhesh Kumar Singh, Paul Karila, Lydia Moll, Owe Orwar
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-74191-w

Calcium Signalling in Breast Cancer Associated Bone Pain

Auteurs: Bortolin, Andrea Neto, Estrela Lamghari, Meriem
Publié dans: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031902

Dorsal Root Ganglia Macrophages Maintain Osteoarthritis Pain

Auteurs: Raoof, Ramin Martin Gil, Christian Lafeber, Floris P. J. G. de Visser, Huub Prado, Judith Versteeg, Sabine Pascha, Mirte N. Heinemans, Anne L. P. Adolfs, Youri Pasterkamp, R. Jeroen Wood, John N. Mastbergen, Simon C. Eijkelkamp, Niels
Publié dans: The Journal of Neuroscience, 2021, ISSN 1529-2401
Éditeur: The Journal of Neuroscience
DOI: 10.1523/jneurosci.1787-20.2021

Mitochondria and sensory processing in inflammatory and neuropathic pain

Auteurs: Silva Santos Ribeiro,P. Willemen,Hanneke L. D. M. Eijkelkamp,Niels
Publié dans: Frontiers in Pain Research, 2022, ISSN 2673-561X
Éditeur: Frontiers
DOI: 10.3389/fpain.2022.1013577

Fibrous dysplasia animal models: A systematic review

Auteurs: Hopkins, Chelsea de Castro, Luis Fernandez Corsi, Alessandro Boyce, Alison Collins, Michael T. Riminucci, Mara Heegaard, Anne-Marie
Publié dans: Bone, 2022, ISSN 8756-3282
Éditeur: Elsevier BV
DOI: 10.1016/j.bone.2021.116270

Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain

Auteurs: Zhang, Xue Ying Barakat, Ahmed Diaz-delCastillo, Marta Vollert, Jan Sena, Emily S. Heegaard, Anne-Marie Rice, Andrew S. C. Soliman, Nadia
Publié dans: Pain, 2022, ISSN 0304-3959
Éditeur: Elsevier BV
DOI: 10.1097/j.pain.0000000000002632

Mechanisms of cancer pain

Auteurs: Haroun,Rayan Wood,John N Sikandar,Shafaq
Publié dans: Frontiers in Pain Research, 2023, ISSN 2673-561X
Éditeur: Frontiers
DOI: 10.3389/fpain.2022.1030899

Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain

Auteurs: van der Vlist, Michiel Raoof, Ramin Willemen, Hanneke L. D. M. Prado, Judith Versteeg, Sabine Martin Gil, Christian Vos, Martijn Lokhorst, Roeland E. Pasterkamp, R. Jeroen Kojima, Toshiyuki Karasuyama, Hajime Khoury-Hanold, William Meyaard, Linde Eijkelkamp, Niels
Publié dans: Neuron, 2022, ISSN 0896-6273
Éditeur: Cell Press
DOI: 10.1016/j.neuron.2021.11.020

The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment

Auteurs: Kalogera, Stefania He, Yi Bay-Jensen, Anne-Christine Gantzel, Thorbjørn Sun, Shu Manon-Jensen, Tina Karsdal, Morten Asser Thudium, Christian S.
Publié dans: Scientific Reports, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-03346-0

Inflammation-induced mitochondrial and metabolic disturbances in sensory neurons control the switch from acute to chronic pain

Auteurs: Willemen, Hanneke L. D. M. Ribeiro, Patrícia Silva Santos Broeks, Melissa Meijer, Nils Versteeg, Sabine Małecki, Jędrzej Falnes, Pål Ø Jans, Judith Eijkelkamp, Niels
Publié dans: bioRxiv, 2022
Éditeur: bioRxiv
DOI: 10.1101/2022.08.29.505682

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