It takes a (microbial) village
One of the reasons fruits, vegetables and whole grains help protect us against non-communicable diseases, such as heart disease, diabetes and cancer, has to do with plant metabolism. Flavonoids are secondary metabolites produced by many plants that help them combat oxidative stress and act as growth regulators. They have antioxidant and anti-inflammatory properties in people. Despite the tremendous interest in flavonoids, their industrial production is currently immature. In nature, they are produced via complex physical and chemical pathways involving trafficking of chemicals throughout plant compartments. To better mimic this and even open the door to the production of flavonoids not seen in nature, the EU-funded SynBio4Flav project is developing synthetic microbial communities with members genetically programmed to execute specific steps in the complex biosynthetic pathways.
Call for proposal
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Funding SchemeRIA - Research and Innovation action