Description du projet
Soulager la pression liée au tri des éléments
La chromatographie liquide à haute performance (CLHP), anciennement appelée chromatographie liquide à haute pression, est une technique couramment utilisée et extrêmement puissante pour séparer les composants d’un mélange liquide. Parmi ses nombreux domaines d’utilisation figurent le développement de produits pharmaceutiques et d’aliments et boissons, la bioanalyse, la médecine clinique et les analyses environnementales. Un échantillon est pompé à haute pression dans un solvant à travers une colonne, et les composés de cet échantillon sont séparés. La PME française Separative a mis au point des colonnes HPLC basse pression réutilisables qui réduisent le coût de la chromatographie conventionnelle d’un facteur de 10 à 50. Le projet Separative, financé par l’UE, aidera l’équipe à réaliser une étude d’automatisation, une analyse de l’organisation de la chaîne de valeur et un examen du mix marketing.
Objectif
SEPARATIVE is a novel chemical purification and analysis method based on a ground-breaking multicapillary material and the related manufacturing process, both protected by four patents. This brand-new material allows to offer reusable low-pressure High-Performance Liquid Chromatography (HPLC) columns. It is the first innovation that achieves chromatographic purification and analysis results without the high pressure and high cost of the state-of-the-art chromatography. SEPARATIVE reduces the cost of current chromatography by a factor of 10-50.
Within the pharmaceutical chromatography market, four types of columns are. Two of these types – flash and preparative – can directly be reached with our first market entrance product range. The flash columns market size is around €240 million and the preparative €110 million. Of those €350 million, we will reach around €240 million with our first business case and then extend the range and the span of the obtainable market. There is a dynamic growth trend with flash columns growing at 10% annually and preparative at 5%.
Being able to use chromatography beyond the experimentation phase would bring several technological advantages to the healthcare industry: Better quality of drugs due to higher purity, lower investments for production plants (savings of 59% for separation), lower manufacturing costs due to better yields (no losses of valuable material in process) and higher security of manufacturing process due to lower volumes of flammable and toxic solvents. This accelerates pharmaceutical innovation and allows citizens to have access to drugs faster.
SEPARATIVE SAS is a start-up hosted at IFPEN (IFP Energies Nouvelles, a major development centre for process industries, renowned worldwide and Nobel Prize for Chemistry in 2005). We are a team of 5 experienced and complementary experts and have access to a great network in chemical engineering as the IFPEN site hosts global leaders such as Total, Solvay, Bluestar and Arkema
Champ scientifique
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Régime de financement
SME-1 - SME instrument phase 1Coordinateur
69190 Saint Fons
France
L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention.