Project description
Relieving the pressure involved in sorting things out
High-performance liquid chromatography (HPLC), formerly known as high-pressure liquid chromatography, is a commonly used and extremely powerful technique for separating the components of a liquid mixture. Among its many areas of use are pharmaceuticals and foods and beverages development, bioanalytics, clinical medicine and environmental analyses. A sample in a solvent is pumped at high pressure through a column, and the compounds in the sample are separated. The French SME Separative has developed reusable low-pressure HPLC columns that reduce the cost of conventional chromatography by a factor of 10–50. The EU-funded Separative project is helping the team conduct an automation study, a value chain organisation analysis and a marketing mix review.
Objective
SEPARATIVE is a novel chemical purification and analysis method based on a ground-breaking multicapillary material and the related manufacturing process, both protected by four patents. This brand-new material allows to offer reusable low-pressure High-Performance Liquid Chromatography (HPLC) columns. It is the first innovation that achieves chromatographic purification and analysis results without the high pressure and high cost of the state-of-the-art chromatography. SEPARATIVE reduces the cost of current chromatography by a factor of 10-50.
Within the pharmaceutical chromatography market, four types of columns are. Two of these types – flash and preparative – can directly be reached with our first market entrance product range. The flash columns market size is around €240 million and the preparative €110 million. Of those €350 million, we will reach around €240 million with our first business case and then extend the range and the span of the obtainable market. There is a dynamic growth trend with flash columns growing at 10% annually and preparative at 5%.
Being able to use chromatography beyond the experimentation phase would bring several technological advantages to the healthcare industry: Better quality of drugs due to higher purity, lower investments for production plants (savings of 59% for separation), lower manufacturing costs due to better yields (no losses of valuable material in process) and higher security of manufacturing process due to lower volumes of flammable and toxic solvents. This accelerates pharmaceutical innovation and allows citizens to have access to drugs faster.
SEPARATIVE SAS is a start-up hosted at IFPEN (IFP Energies Nouvelles, a major development centre for process industries, renowned worldwide and Nobel Prize for Chemistry in 2005). We are a team of 5 experienced and complementary experts and have access to a great network in chemical engineering as the IFPEN site hosts global leaders such as Total, Solvay, Bluestar and Arkema
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences economics and business economics production economics productivity
- engineering and technology chemical engineering separation technologies
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
69190 Saint Fons
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.