Surveillance mechanisms regulating nuclear envelope architecture and homeostasis

Project Information

ProteoNE_dynamics

Grant agreement ID: 817708

DOI

10.3030/817708

Project closed

EC signature date 21 January 2019

Start date 1 July 2019

End date 30 June 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 610,00

EU contribution

€ 1 999 610,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Mechanisms of transmembrane domain recognition during endoplasmic reticulum quality control

Author(s): Nikita Sergejevs, Pedro Carvalho
Published in: Current Opinion in Cell Biology, Issue 96, 2026, Page(s) 102580, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2025.102580

Regulated degradation of the inner nuclear membrane protein SUN2 maintains nuclear envelope architecture and function

Author(s): Logesvaran Krshnan, Wingyan Skyla Siu, Michael Van de Weijer, Daniel Hayward, Elena Navarro Guerrero, Ulrike Gruneberg, Pedro Carvalho
Published in: eLife, Issue 11, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.81573

The derlin Dfm1 couples retrotranslocation of a folded protein domain to its proteasomal degradation

Author(s): Daniela G. Vitali, Daniel Fonseca, Pedro Carvalho
Published in: Journal of Cell Biology, Issue 223, 2024, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.202308074

Endoplasmic Reticulum–Associated Protein Degradation

Author(s): Logesvaran Krshnan, Michael L. van de Weijer, Pedro Carvalho
Published in: Cold Spring Harbor Perspectives in Biology, 2022, Page(s) a041247, ISSN 1943-0264
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/cshperspect.a041247

Order through destruction: how ER-associated protein degradation contributes to organelle homeostasis

Author(s): Pedro Carvalho
Published in: The EMBO Journal, 2022, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2021109845

Making and breaking the inner nuclear membrane proteome

Author(s): Lilli Hahn Pedro Carvalho
Published in: Current Opinion in Cell Biology, 2022, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2022.102115

Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

Author(s): Zhe Ji, Wing-Yan Skyla Siu, Maria Emilia Dueñas, Leonie Müller, Matthias Trost, Pedro Carvalho
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-58681-x