Apoptotic foci: composition, structure and dynamics

Project Information

APOSITE

Grant agreement ID: 817758

DOI 10.3030/817758

EC signature date 18 February 2019

Start date 1 April 2019

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

UNIVERSITAT ZU KOLN
Germany

Publications

Peer reviewed articles (8)

Pore formation in regulated cell death

Author(s): Hector Flores‐Romero, Uris Ros, Ana J Garcia‐Saez
Published in: The EMBO Journal, Issue 39/23, 2020, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2020105753

BCL‐2‐family protein tBID can act as a BAX‐like effector of apoptosis

Author(s): Hector Flores‐Romero; Lisa Hohorst; Malina John; Marie‐Christine Albert; Louise E King; Laura Beckmann; Tamas Szabo; Vanessa Hertlein; Xu Luo; Andreas Villunger; Lukas P Frenzel; Hamid Kashkar; Ana J Garcia‐Saez
Published in: The EMBO Journal, 2022, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2021108690

Apoptosis regulation at the mitochondria membrane level

Author(s): Shashank Dadsena, Louise E. King, Ana J. García-Sáez
Published in: Biochimica et Biophysica Acta (BBA) - Biomembranes, Issue 1863/12, 2021, Page(s) 183716, ISSN 0005-2736
Publisher: Elsevier BV
DOI: 10.1016/j.bbamem.2021.183716

The Mysteries around the BCL-2 Family Member BOK

Author(s): Raed Shalaby, Hector Flores-Romero, Ana J. García-Sáez
Published in: Biomolecules, Issue 10/12, 2020, Page(s) 1638, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom10121638

DRP1 interacts directly with BAX to induce its activation and apoptosis

Author(s): Andreas Jenner; Aida Peña‐Blanco; Raquel Salvador‐Gallego; Begoña Ugarte‐Uribe; Cristiana Zollo; Tariq Ganief; Jan Bierlmeier; Markus Mund; Jason E Lee; Jonas Ries; Dirk Schwarzer; Boris Macek; Ana J Garcia‐Saez
Published in: The EMBO Journal, Issue 1, 2022, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2021108587

Techniques for studying membrane pores

Author(s): Uris Ros, Lohans Pedrera, Ana J. Garcia-Saez
Published in: Current Opinion in Structural Biology, Issue 69, 2021, Page(s) 108-116, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2021.03.012

The Incomplete Puzzle of the BCL2 Proteins

Author(s): Flores-Romero, García-Sáez
Published in: Cells, Issue 8/10, 2019, Page(s) 1176, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells8101176

The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

Author(s): Katia Cosentino; Vanessa Hertlein; Andreas Jenner; Timo Dellmann; Milos Gojkovic; Aida Peña-Blanco; Shashank Dadsena; Noel Wajngarten; John S.H. Danial; Jervis Vermal Thevathasan; Markus Mund; Jonas Ries; Ana J. Garcia-Saez
Published in: Molecular Cell, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.01.008