Regulation of Brain Macrophage Development and Function

Project Information

MADEFUN

Grant agreement ID: 819229

DOI

10.3030/819229

Project closed

EC signature date 30 January 2019

Start date 1 June 2019

End date 31 May 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 995 500,00

EU contribution

€ 1 995 500,00

Coordinated by

UNIVERSITAT ZURICH
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development

Author(s): Sebastian G. Utz, Peter See, Wiebke Mildenberger, Morgane Sonia Thion, Aymeric Silvin, Mirjam Lutz, Florian Ingelfinger, Nirmala Arul Rayan, Iva Lelios, Anne Buttgereit, Kenichi Asano, Shyam Prabhakar, Sonia Garel, Burkhard Becher, Florent Ginhoux, Melanie Greter
Published in: Cell, Issue 181/3, 2020, Page(s) 557-573.e18, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2020.03.021

Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity

Author(s): Lorenzo Gesuita; Anna Cavaccini; Ali Özgür Argunsah; Emilia Favuzzi; Leena Ali Ibrahim; Tevye Jason Stachniak; Martina De Gennaro; Sebastian Utz; Melanie Greter; Theofanis Karayannis
Published in: Cell Reports, Issue 1, 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.111209

Central Nervous System Macrophages in Health and Disease

Author(s): Hannah Van Hove, Donatella De Feo, Melanie Greter, Burkhard Becher
Published in: Annual Review of Immunology, Issue 43, 2025, Page(s) 589-613, ISSN 0732-0582
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-immunol-082423-041334

Lactation-associated macrophages exist in murine mammary tissue and human milk

Author(s): Cansever, Dilay; Petrova, Ekaterina; Krishnarajah, Sinduya; Mussak, Caroline; Welsh, Christina A; Mildenberger, Wiebke; Mulder, Kevin; Kreiner, Victor; Roussel, Elsa; Stifter, Sebastian A; Andreadou, Myrto; Zwicky, Pascale; Jurado, Nicole Puertas; Rehrauer, Hubert; Tan, Ge; Liu, Zhaoyuan; Blériot, Camille; Ronchi, Francesca; Macpherson, Andrew J; Ginhoux, Florent; Natalucci, Giancarlo; Becher, Bu
Published in: Nature Immunology, Issue 1, 2023, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-023-01530-0

Pericytes regulate vascular immune homeostasis in the CNS.

Author(s): Török, Orsolya; Schreiner, Bettina; Schaffenrath, Johanna; Tsai, Hsing-Chuan; Maheshwari, Upasana; Stifter, Sebastian A; Welsh, Christina; Amorim, Ana; Sridhar, Sucheta; Utz, Sebastian G; Mildenberger, Wiebke; Nassiri, Sina; Delorenzi, Mauro; Aguzzi, Adriano; Han, May H; Greter, Melanie; Becher, Burkhard; Keller, Annika
Published in: PNAS, Issue 1, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2016587118

Interleukin-34-dependent perivascular macrophages promote vascular function in the brain

Author(s): Hannah Van Hove, Chaim Glück, Wiebke Mildenberger, Ekaterina Petrova, Upasana Maheshwari, Philipp Häne, Victor Kreiner, Mitchell Bijnen, Caroline Mussak, Sebastian G. Utz, Jeanne Droux, Florian Ingelfinger, Christian Ashworth, Sebastian A. Stifter, Elsa Roussel, Iva Lelios, Marijne Vermeer, Sheng-Fu Huang, Quanyu Zhou, Zhenyue Chen, Charlotte Calvet, Soline Bourgeois, Johanna Schaffenrath, Danie
Published in: Immunity, Issue 58, 2025, Page(s) 1289-1305.e8, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2025.04.003

Microglia control small vessel calcification via TREM2.

Author(s): Zarb, Yvette; Sridhar, Sucheta; Nassiri, Sina; Utz, Sebastian Guido; Schaffenrath, Johanna; Maheshwari, Upasana; Rushing, Elisabeth J; Nilsson, K Peter R; Delorenzi, Mauro; Colonna, Marco; Greter, Melanie; Keller, Annika
Published in: Science advances, Issue vol. 7, no. 9, pp. 135-145, 2021, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.abc4898

Other (2)

BAM! Pathogen control at the brain border

Author(s): Stifter, Sebastian A; Greter, Melanie
Published in: Immunity, Issue 2, 2022
Publisher: CellPress
DOI: 10.1016/j.immuni.2022.10.013

Diversity and function of brain-associated macrophages

Author(s): Wiebke Mildenberger
Published in: ScienceDirect, 2022
Publisher: Elsevier
DOI: 10.1016/j.coi.2022.102181