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Targeting the adaptive capacity of prostate cancer through the manipulation of transcriptional and metabolic traits

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Publications

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome

Author(s): Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Aitor Bermejo-Arteagabeitia, Carolina Da Fonseca, Orhi Barroso-Gomila, Mikel Azkargorta, Ibon Iloro, Olatz Pampliega, Ricardo Andrade, Natalia Martín-Martín, Tess C Branon, Alice Y Ting, Jose A Rodríguez, Arkaitz Carracedo, Felix Elortza, James D Sutherland, Rosa Barrio
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
DOI: 10.7554/elife.55957

Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis

Author(s): Parastoo Shahrouzi, Ianire Astobiza, Ana R. Cortazar, Verónica Torrano, Alice Macchia, Juana M. Flores, Chiara Niespolo, Isabel Mendizabal, Ruben Caloto, Amaia Ercilla, Laura Camacho, Leire Arreal, Maider Bizkarguenaga, Maria L. Martinez-Chantar, Xose R. Bustelo, Edurne Berra, Endre Kiss-Toth, Guillermo Velasco, Amaia Zabala-Letona, Arkaitz Carracedo
Published in: Cancers, Issue 12/9, 2020, Page(s) 2593, ISSN 2072-6694
DOI: 10.3390/cancers12092593

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer

Author(s): Ivana Hermanova, Patricia Zúñiga-García, Alfredo Caro-Maldonado, Sonia Fernandez-Ruiz, Fernando Salvador, Natalia Martín-Martín, Amaia Zabala-Letona, Marc Nuñez-Olle, Verónica Torrano, Laura Camacho, Jose M. Lizcano, Ana Talamillo, Suzanne Carreira, Bora Gurel, Ana R. Cortazar, Marc Guiu, Jose I. López, Anabel Martinez-Romero, Ianire Astobiza, Lorea Valcarcel-Jimenez, Mar Lorente, Amaia Ar
Published in: Journal of Experimental Medicine, Issue 217/6, 2020, ISSN 0022-1007
DOI: 10.1084/jem.20191787

Multiplex SERS Detection of Metabolic Alterations in Tumor Extracellular Media

Author(s): Javier Plou, Isabel García, Mathias Charconnet, Ianire Astobiza, Clara García‐Astrain, Cristiano Matricardi, Agustín Mihi, Arkaitz Carracedo, Luis M. Liz‐Marzán
Published in: Advanced Functional Materials, Issue 30/17, 2020, Page(s) 1910335, ISSN 1616-301X
DOI: 10.1002/adfm.201910335

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton

Author(s): Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Natalia Martín-Martín, Amaia Ercilla, Jose A. Rodríguez, Arkaitz Carracedo, James D. Sutherland, Rosa Barrio
Published in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X
DOI: 10.3389/fcell.2021.624089

Phosphoinositide 3-Kinase–Regulated Pericyte Maturation Governs Vascular Remodeling

Author(s): Ana M. Figueiredo, Pilar Villacampa, Rodrigo Diéguez-Hurtado, Juan José Lozano, Piotr Kobialka, Ana Rosa Cortazar, Anabel Martinez-Romero, Ana Angulo-Urarte, Claudio A. Franco, Marc Claret, Ana María Aransay, Ralf H. Adams, Arkaitz Carracedo, Mariona Graupera
Published in: Circulation, Issue 142/7, 2020, Page(s) 688-704, ISSN 0009-7322
DOI: 10.1161/circulationaha.119.042354

CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo.

Author(s): Abdullah Alajati; D'ambrosio Mariantonietta; Martina Troiani; Simone Mosole; Laura Pellegrini; Jingjing Chen; Ajinkya Revandkar; Marco Bolis; Jean-Philippe Theurillat; Ilaria Guccini; Marco Losa; Arianna Calcinotto; Gaston De Bernardis; Emiliano Pasquini; Rocco D'Antuono; Adam Sharp; Ines Figueiredo; Daniel Nava Rodrigues; Jonathan C. Welti; Veronica Gil; Wei Yuan; Tatjana Vlajnic; Lukas Bubendorf
Published in: Journal of Clinical Investigation 130(5) 2435-2450, Issue 1, 2020, ISSN 0021-9738
DOI: 10.3929/ethz-b-000409240