Form and Function of the Mitochondrial Retrograde Response

Project Information

FIRM

Grant agreement ID: 819600

DOI

10.3030/819600

EC signature date 13 March 2019

Start date 1 April 2019

End date 31 March 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 450 060,00

EU contribution

€ 1 450 060,00

Coordinated by

QUEEN MARY UNIVERSITY OF LONDON
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response

Author(s): Radha Desai, Daniel A. East, Liana Hardy, Danilo Faccenda, Manuel Rigon, James Crosby, María Soledad Alvarez, Aarti Singh, Marta Mainenti, Laura Kuhlman Hussey, Robert Bentham, Gyorgy Szabadkai, Valentina Zappulli, Gurtej K. Dhoot, Lisa E. Romano, Dong Xia, Isabelle Coppens, Anne Hamacher-Brady, J. Paul Chapple, Rosella Abeti, Roland A. Fleck, Gema Vizcay-Barrena, Kenneth Smith, Michelangelo Camp
Published in: Science Advances, Issue 6/51, 2020, Page(s) eabc9955, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abc9955

NH-sulfoximine: A novel pharmacological inhibitor of the mitochondrial F 1 F o -ATPase, which suppresses viability of cancerous cells

Author(s): Daniela Strobbe, Rosalba Pecorari, Oriana Conte, Antonella Minutolo, Christine M M Hendrik, Stefan Wiezorek, Danilo Faccenda, Rosella Abeti, Carla Montesano, Carsten Bolm, Michelangelo Campanella
Published in: British Journal of Pharmacology, 2021, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.15279

Mitochondria Regulate Inflammatory Paracrine Signalling in Neurodegeneration

Author(s): Danilo Faccenda, Michelangelo Campanella
Published in: Journal of Neuroimmune Pharmacology, Issue 15/4, 2020, Page(s) 565-566, ISSN 1557-1890
Publisher: Springer Verlag
DOI: 10.1007/s11481-020-09952-5

The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity

Author(s): Michele Frison, Danilo Faccenda, Rosella Abeti, Manuel Rigon, Daniela Strobbe, Britannie S. England-Rendon, Diana Cash, Katy Barnes, Mona Sadeghian, Marija Sajic, Lisa A. Wells, Dong Xia, Paola Giunti, Kenneth Smith, Heather Mortiboys, Federico E. Turkheimer, Michelangelo Campanella
Published in: Molecular Psychiatry, 2021, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-021-01050-z

Links between mitochondrial retrograde response and mitophagy in pathogenic cell signalling

Author(s): Daniela Strobbe, Soumya Sharma, Michelangelo Campanella
Published in: Cellular and Molecular Life Sciences, 2021, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-021-03770-5

Pyroptosis targeting via mitochondria: An educated guess to innovate COVID-19 therapies

Author(s): Aarti Singh, Daniela Strobbe, Michelangelo Campanella
Published in: British Journal of Pharmacology, 2022, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.15670

Ca 2+ Transportome and the Interorganelle Communication in Hepatocellular Carcinoma

Author(s): Hong-Toan Lai, Reynand Jay Canoy, Michelangelo Campanella, Yegor Vassetzky, Catherine Brenner
Published in: Cells, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11050815

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Author(s): Daniel J. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H. Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E. Adamopoulos, Khosrow Adeli, Timon E. Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B. Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N. Agrewala, Alexander A
Published in: Autophagy, Issue 17/1, 2021, Page(s) 1-382, ISSN 1554-8627
Publisher: Landes Bioscience
DOI: 10.1080/15548627.2020.1797280

The ATPase Inhibitory Factor 1 (IF1) regulates the expression of the mitochondrial Ca2+ uniporter (MCU) via the AMPK/CREB pathway.

Author(s): Danilo Faccenda; Giulia Gorini; Adam Jones; Claire Thornton; Alessandra Baracca; Giancarlo Solaini; Michelangelo Campanella
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Issue 1, 2021, ISSN 0167-4889
Publisher: Elsevier BV
DOI: 10.1016/j.bbamcr.2020.118860

Pharmacological advances in mitochondrial therapy

Author(s): Aarti Singh, Danilo Faccenda, Michelangelo Campanella
Published in: EBioMedicine, Issue 65, 2021, Page(s) 103244, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2021.103244

Non-peer reviewed articles (1)

Mitochondria ensure immune surveillance by retro-communication with the nucleus

Author(s): Manuel Rigon, Amelia R Townley, Michelangelo Campanella
Published in: Cell Metabolism, 2021, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2021.04.013