Deciphering and predicting the evolution of cancer cell populations

Información del proyecto

CANCEREVO

Identificador del acuerdo de subvención: 820137

DOI 10.3030/820137

Fecha de la firma de la CE 23 Enero 2019

Fecha de inicio 1 Marzo 2019

Fecha de finalización 31 Marzo 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 2 000 000,00

Aportación de la UE € 2 000 000,00

Coordinado por

QUEEN MARY UNIVERSITY OF LONDON
United Kingdom

Publicaciones

Peer reviewed articles (5)

Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer

Autores: Andrew Woolston, Louise J. Barber, Beatrice Griffiths, Oriol Pich, Nuria Lopez-Bigas, Nik Matthews, Sheela Rao, David Watkins, Ian Chau, Naureen Starling, David Cunningham, Marco Gerlinger
Publicado en: Nature Ecology & Evolution, Edición 5/7, 2021, Página(s) 1024-1032, ISSN 2397-334X
Editor: Nature Ecology and Evolution
DOI: 10.1038/s41559-021-01470-8

Circulating Tumour DNA Sequencing Identifies a Genetic Resistance-Gap in Colorectal Cancers with Acquired Resistance to EGFR-Antibodies and Chemotherapy

Autores: Franciele H. Knebel, Louise J. Barber, Alice Newey, Dimitrios Kleftogiannis, Andrew Woolston, Beatrice Griffiths, Kerry Fenwick, Fabiana Bettoni, Maurício Fernando Silva Almeida Ribeiro, Leonardo da Fonseca, Frederico Costa, Fernanda Cunha Capareli, Paulo M. Hoff, Jorge Sabbaga, Anamaria A. Camargo, Marco Gerlinger
Publicado en: Cancers, Edición 12/12, 2020, Página(s) 3736, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123736

Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma

Autores: Michael Davidson, Louise J. Barber, Andrew Woolston, Catherine Cafferkey, Sonia Mansukhani, Beatrice Griffiths, Sing-Yu Moorcraft, Isma Rana, Ruwaida Begum, Ioannis Assiotis, Nik Matthews, Sheela Rao, David Watkins, Ian Chau, David Cunningham, Naureen Starling, Marco Gerlinger
Publicado en: Cancers, Edición 11/5, 2019, Página(s) 736, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11050736

Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

Autores: Alice Newey, Beatrice Griffiths, Justine Michaux, Hui Song Pak, Brian J. Stevenson, Andrew Woolston, Maria Semiannikova, Georgia Spain, Louise J. Barber, Nik Matthews, Sheela Rao, David Watkins, Ian Chau, George Coukos, Julien Racle, David Gfeller, Naureen Starling, David Cunningham, Michal Bassani-Sternberg, Marco Gerlinger
Publicado en: Journal for ImmunoTherapy of Cancer, Edición 7/1, 2019, ISSN 2051-1426
Editor: Biomedcentral
DOI: 10.1186/s40425-019-0769-8

Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes

Autores: Benjamin R Challoner, Katharina von Loga, Andrew Woolston, Beatrice Griffiths, Nanna Sivamanoharan, Maria Semiannikova, Alice Newey, Louise J Barber, David Mansfield, Lindsay C Hewitt, Yuichi Saito, Naser Davarzani, Naureen Starling, Alan Melcher, Heike I Grabsch, Marco Gerlinger
Publicado en: JNCI: Journal of the National Cancer Institute, Edición monthly, 2020, ISSN 0027-8874
Editor: Oxford University Press
DOI: 10.1093/jnci/djaa051