Leveraging room temperature diamond quantum dynamics to enable safe, first-of-its-kind, multimodal cardiac imaging

Project Information

MetaboliQs

Grant agreement ID: 820374

DOI 10.3030/820374

Project closed

EC signature date 15 October 2018

Start date 1 October 2018

End date 31 March 2022

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 6 667 801,25

EU contribution € 6 667 801,25

Coordinated by

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

Deliverables

Other (2)

MetaboliQs medical user workshop

The workshop will combine lectures by key opinion leaders and live demonstrations to raise awareness of our technology within the cardiovascular MRI community

MetaboliQs Public website

Production of a public website to promote the project progress and results

Publications

Peer reviewed articles (22)

Growth defects in heteroepitaxial diamond

Author(s): V. Lebedev, J. Engels, J. Kustermann, J. Weippert, V. Cimalla, L. Kirste, C. Giese, P. Quellmalz, A. Graff, F. Meyer, M. Höfer, V. Sittinger
Published in: Journal of Applied Physics, Issue 129, 2021, Page(s) 165301, ISSN 1089-7550
Publisher: AIP Publishing
DOI: 10.1063/5.0045644

pH Dependence of T2 for Hyperpolarizable 13C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging

Author(s): Martin Grashei, Christian Hundshammer, Frits H.A. van Heijster, Geoffrey J. Toppping, Franz Schilling
Published in: Pharmaceuticals, Issue 14 (4), 2021, Page(s) 327, ISSN 1424-8247
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph14040327

Long-Timescale Magnetization Ordering Induced by an Adsorbed Chiral Monolayer on Ferromagnets

Author(s): Idan Meirzada, Nir Sukenik, Galya Haim, Shira Yochelis, Yossi Paltiel, Nir Bar-Gill
Published in: Arxiv, 2021, ISSN 2331-8422
Publisher: Cornell University
DOI: 10.48550/arxiv.2103.04772

Long range magnetic dipole-dipole interaction mediated by a superconductor

Author(s): Yoav Romach, Tal Wasserman, Shai Tishby, Nir Bar-Gill
Published in: Phys. Rev. Research 3, Issue 3, 2021, Page(s) 033280, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.3.033280

Preferential Placement of Aligned Nitrogen Vacancy Centers in Chemical Vapor Deposition Overgrown Diamond Microstructures

Author(s): A. Götze, N. Striegler, A. Marshall, P. Neumann, C. Giese, P. Quellmalz, P. Knittel
Published in: Phys. Status Solidi RRL, Issue 19, 2022, Page(s) 2100373, ISSN 1862-6270
Publisher: Wiley
DOI: 10.1002/pssr.202100373

Hyperpolarized 13C Spectroscopy with Simple Slice-and-Frequency-Selective Excitation

Author(s): Geoffrey J. Topping, Irina Heid, Marija Trajkovic-Arsic, Lukas Kritzner, Martin Grashei, Christian Hundshammer, Maximilian Aigner, Jason G. Skinner, Rickmer Braren, Franz Schilling
Published in: Biomedicines, Issue 9(2), 2021, Page(s) 121, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9020121

Finding the nitrogen-vacancy singlet manifold energy level using charge conversion pulse sequences

Author(s): I. Meirzada, S. A. Wolf, N. Bar-Gill
Published in: Arxiv, 2021, ISSN 2331-8422
Publisher: Cornell University
DOI: 10.48550/arxiv.2011.08537

High-Sensitivity, High-Resolution Detection of Reactive Oxygen Species Concentration Using NV Centers

Author(s): Yoav Ninio, Nir Waiskopf, Idan Meirzada, Yoav Romach, Galya Haim, Shira Yochelis, Uri Banin, Nir Bar-Gill
Published in: Arxiv, 2021, ISSN 2331-8422
Publisher: Cornell University
DOI: 10.48550/arxiv.2107.00398

On the robustness of the NV - NMR spectrometer setup to magnetic field inhomogeneities

Author(s): Yotam Vaknin, Benedikt Tratzmiller, Tuvia Gefen, Ilai Schwartz, Martin Plenio, Alex Retzker
Published in: Arxiv, 2020, ISSN 2331-8422
Publisher: Cornel University

Blueprint for nanoscale NMR

Author(s): I. Schwartz1; J. Rosskopf, S. Schmitt, B. Tratzmiller, Q. Chen, L.P. McGuinness, F. Jelezko, M.B. Plenio
Published in: Arxiv, 2017, ISSN 2331-8422
Publisher: Cornel University

Efficient and robust signal sensing by sequences of adiabatic chirped pulses

Author(s): Genko T. Genov, Yachel Ben-Shalom, Fedor Jelezko, Alex Retzker, Nir Bar-Gill
Published in: Arxiv, 2020, ISSN 2331-8422
Publisher: Cornel University

Robust mode conversion in NV centers using exceptional points

Author(s): A. Pick, S. Silberstein, N. Moiseyev, N. Bar-Gill
Published in: Physical Review Research, Issue 1/1, 2019, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.1.013015

Measuring Environmental Quantum Noise Exhibiting a Nonmonotonic Spectral Shape

Author(s): Y. Romach, A. Lazariev, I. Avrahami, F. Kleißler, S. Arroyo-Camejo, N. Bar-Gill
Published in: Physical Review Applied, Issue 11/1, 2019, ISSN 2331-7019
Publisher: American Physical Society
DOI: 10.1103/physrevapplied.11.014064

Enhanced spin state readout of nitrogen-vacancy centers in diamond using infrared fluorescence

Author(s): I. Meirzada, S. A. Wolf, A. Naiman, U. Levy, N. Bar-Gill
Published in: Physical Review B, Issue 100/12, 2019, ISSN 2469-9950
Publisher: American Physical Society
DOI: 10.1103/physrevb.100.125436

Characterizing spin-bath parameters using conventional and time-asymmetric Hahn-echo sequences

Author(s): D. Farfurnik, N. Bar-Gill
Published in: Physical Review B, Issue 101/10, 2020, ISSN 2469-9950
Publisher: American Physical Society
DOI: 10.1103/physrevb.101.104306

Hamiltonian engineering of general two-body spin-1/2 interactions

Author(s): K. I. O. Ben 'Attar, D. Farfurnik, N. Bar-Gill
Published in: Physical Review Research, Issue 2/1, 2020, ISSN 2643-1564
Publisher: PHYSICAL REVIEW RESEARCH
DOI: 10.1103/physrevresearch.2.013061

Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei

Author(s): Geoffrey J. Topping, Christian Hundshammer, Luca Nagel, Martin Grashei, Maximilian Aigner, Jason G. Skinner, Rolf F. Schulte, Franz Schilling
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine, Issue 33/2, 2020, Page(s) 221-256, ISSN 0968-5243
Publisher: Springer Verlag
DOI: 10.1007/s10334-019-00807-6

Microstructural and optical emission properties of diamond multiply twinned particles

Author(s): Vadim Lebedev, Taro Yoshikawa, Christoph Schreyvogel, Lutz Kirste, Jürgen Weippert, Michael Kunzer, Andreas Graff, Oliver Ambacher
Published in: Journal of Applied Physics, Issue 127/2, 2020, Page(s) 025303, ISSN 0021-8979
Publisher: American Institute of Physics
DOI: 10.1063/1.5127170

The diamond quantum revolution

Author(s): Matthew Markham, Daniel Twitchen
Published in: physicsworld, 2020, ISSN 0953-8585
Publisher: Institute of Physics

Prediction of multiple pH compartments by deep learning in magnetic resonance spectroscopy with hyperpolarized 13C-labelled zymonic acid

Author(s): Wai-Yan Ryana Fok, Martin Grashei, Jason G. Skinner, Björn H. Menze, Franz Schilling
Published in: EJNMMI Research, Issue 12:24, 2022, ISSN 2191-219X
Publisher: Springer Berlin
DOI: 10.1186/s13550-022-00894-y

Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi‐echo balanced steady‐state free precession at 3 T

Author(s): Christoph A. Müller, Christian Hundshammer, Miriam Braeuer, Jason G. Skinner, Stephan Berner, Jochen Leupold, Stephan Düwel, Stephan G. Nekolla, Sven Månsson, Adam E Hansen, Dominik von Elverfeldt, Jan H. Ardenkjaer‐Larsen, Franz Schilling, Markus Schwaiger, Jürgen Hennig, Jan‐Bernd Hövener
Published in: NMR in Biomedicine, Issue 33(6), 2020, Page(s) e4291, ISSN 1099-1492
Publisher: Wiley
DOI: 10.1002/nbm.4291

Spin-bath polarization via disentanglement

Author(s): D. D. Bhaktavatsala Rao, Arnab Ghosh, David Gelbwaser-Klimovsky, Nir Bar-Gill, Gershon Kurizki
Published in: Arxiv, 2020, ISSN 2331-8422
Publisher: Cornell University
DOI: 10.48550/arxiv.1912.00613