The next phase of digital transformation has arrived in the field of Electronic Smart Systems (ESS), reaching to the far edges of the networks, with connections to billions of devices and objects collecting and transmitting data from ever evolving sensors. This new wave of innovation extends digital intelligence beyond dedicated devices making sensors integral in digital ecosystems. Smart sensors have evolved from discrete devices designed to detect specific properties (e.g. light, heat, motion), to fully integrated sensor systems, offering enhanced computing capabilities, connected within any number of autonomous systems. There has been a shift towards miniaturization of ESS, bringing new concepts and technologies that will benefit the environment of smart cities, such as air quality monitoring, temperature, humidity, noise and occupancy as well as people- or asset- security (imaging, tracking, fingerprint, data privacy, cybersecurity). In order to release the potentiality of ESSs, it is crucial to optimize the size, cost, materials, design and manufacturing processes. AMANDA develops a unique Autonomous Smart Sensing Card (ASSC) with the size, feel and look of a credit card, ideal for easy deploy in buildings (smart living environments) or as wearables (bikes, valuable assets, people). The project covers the triangle of experimentation, development and standardization in order to optimise the materials behaviour, connectivity, miniaturization, power consumption, security, intelligence, design and cost. AMANDA’s vision is to overcome the existing technological challenges and achieve the development of a user-friendly wearable platform not only for indoor & outdoor environmental sensing, but also for asset- and people- tracking. A combination of new developed, optimised, existing innovative off-the-shelf or close-to-commercialization sensor technologies are selected and integrated into the ASSC, including air quality, temperature, humidity, image, long-range tracking, innovative PVs and batteries, all packed in under 3mm thickness will introduce technical breakthroughs that will boost further miniaturisation, offer increased sensitivity, small footprint, ultra-low power consumption and a maintenance-free lifetime of more than 10 years.