Project description
A transcontinental collaboration to improve data-driven cardiovascular research
The translation of research findings into clinical practice is often impeded by fragmented efforts and lack of information on available data resources. The EU-funded euCanSHare project is developing the first centralised and secure platform for data sharing and analysis for cardiovascular research. The platform will integrate major cardiovascular data sources totalling one million records from Europe and Canada. Extensive functionalities will improve access to information and ensure correct data deposition, quality control and harmonisation. The platform will support biomarker validation, knowledge discovery, cardiovascular risk assessment as well as public health research. Ultimately, the euCanSHare platform will accelerate data-driven research efforts for personalised medicine in cardiology.
Objective
euCanSHare will develop the first centralised, secure and sustainable platform for enhanced cross-border data sharing and multi-cohort personalised medicine research in cardiology. At its heart, the platform will contain the most comprehensive cardiovascular data catalogue ever assembled, which will facilitate data discoverability and exploitation in full alignment with the FAIR principles. The project will implement the interoperability of currently fragmented yet mature IT solutions developed by the consortium members for generating a comprehensive multi-functionality platform. It will also integrate major cardiovascular data sources from Europe and Canada, including the renowned MORGAM, BiomarCaRE and CAHHM initiatives. euCanSHare’s legal framework will be built through detailed ethical and legal interoperability analysis, while investigating innovative solutions for promoting responsible Open Science based on the emerging blockchain technology.
Initially populated with 35 European and Canadian cohorts (corresponding to about one million records), the platform will provide extensive functionalities, including for data deposition, data harmonisation and quality control, which will support the integration of new cohorts beyond the duration of the project, thus ensuring its scalability. Moreover, sustainability will be targeted by leveraging through our multi-disciplinary partners the most established data infrastructures, namely ELIXIR, EGA, BBMRI and euro-BioImaging in Europe, as well as Maelstrom from Canada. The unique features of the platform will be demonstrated and adjusted through several use cases, including for biomarker validation, knowledge discovery, cardiovascular risk assessment, public health research and industry-driven studies. Furthermore, intensive outreach campaigns and hands-on workshops will be organised to attract a range of stakeholders, data providers and end-users from the academic, public health and industrial sectors.
Fields of science
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Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
08007 Barcelona
Spain
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Participants (19)
H3H 2R9 Montreal
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20251 Hamburg
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00198 Rome
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
3015 GD Rotterdam
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E1 4NS London
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H3A0G4 Montreal
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3000 Leuven
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08034 Barcelona
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08003 Barcelona
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06903 Biot Sophia Antipolis
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8010 Graz
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
602 00 Brno
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
04109 Leipzig
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
70029 Kys
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L8S 4L8 Hamilton
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00271 Helsinki
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17489 Greifswald
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08029 BARCELONA
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
08002 Barcelona
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