Deliverables
Analysis of the data processed in PRIMAGE Platform.
Visual tools for in-silico modelsVisual tools for insilico models
Beta version of the diagnostic moduleBeta PRIMAGE Diagnostic module combining imaging and biological biomarkers in charge of generation of radiomic data for the clinical prospective studies
Deployment of the final, refined version of the Model Execution EnvironmentDeployment of the final refined version of the Model Execution Environment
Deployment of the final, refined version of hybrid open cloud and processing middlewareDeployment of the final refined version of the cloud infrastructure
Deployment of intermediate version of hybrid open cloud and processing middlewareDeployment of an intermediate version of Hybrid Open Datacloud and processing middleware layer.
Deployment of an intermediate version of the Model Execution EnvironmentDeployment of an intermediate version of the Model Execution Environment encompassing all fundamental functionality for PRIMAGE simulation pipeline executions
Record of dissemination and communication activities in year 3 and plan for year 4 including preliminary exploitation plan
Advancements of in-silico model for simulation of solid tumour growth at whole tumour scaleAdvancements of insilico model for solid tumour growth simulation enabling comparison of untreated and treated patient
Readiness to start recruitment for clinical testsApproval from Ethics Committees at each hospital to start recruitment.
Ethics review planEthical review
Definition of data requirements, e-forms, QC procedures and signed authorisationsDefinition of data requirements eforms control procedures for data quality and signed authorisations with different data holders to reuse existing datasets
First year plan for dissemination and communication activities, incl website and dissemination toolkit 1First year plan for dissemination and communication activities: Website & dissemination toolkit 1.
Record of dissemination and communication activities in year 2 and plan for year 3Record of dissemination and communication actions in year 2 plan for year 3
Record of dissemination and communication activities in year 1 and plan for year 2, incl. dissemination toolkit 2Advancements of in-silico models for mechanisms of tumour cells interactions, enabling comparison of untreated and treated patient.
Advancements of insilico models for mechanisms of tumour cells interactions enabling comparison of untreated and treated patient
Conclusions from PRIMAGE Platform clinical assessmentConclusions on the performance and usability of the platform from the perspective of the paediatric oncologists and radiologists
Contribution to standards for image acquisition, image biomarker extraction and formatContribution to standardisation of protocols for image acquisition imaging biomarker extraction and format
Advancements of in-silico model for simulation of effect of pharmacology on sub-cellular behaviour of tumour cellsAdvancements of insilico model for simulation of effect of pharmacology on subcellular behaviour of tumour cells
Final version of PRIMAGE platform.
Publications
Author(s):
Michela Gabelloni, Lorenzo Faggioni, Rita Borgheresi, Giuliana Restante, Jorge Shortrede, Lorenzo Tumminello, Camilla Scapicchio, Francesca Coppola, Dania Cioni, Ignacio Gómez-Rico, Luis Martí-Bonmatí, Emanuele Neri
Published in:
European Radiology, 2022, ISSN 0938-7994
Publisher:
Springer Verlag
DOI:
10.1007/s00330-021-08431-6
Author(s):
Diana Veiga-Canuto; Leonor Cerdà-Alberich; Cinta Sangüesa Nebot; Blanca Martínez de las Heras; Ulrike Pötschger; Michela Gabelloni; José Miguel Carot Sierra; Sabine Taschner-Mandl; Vanessa Düster; Adela Cañete; Ruth Ladenstein; Emanuele Neri; Luis Martí-Bonmatí
Published in:
Cancers, 2022, ISSN 2072-6694
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/cancers14153648
Author(s):
Thilo Spinner; Udo Schlegel; Hanna Schäfer; Mennatallah El-Assady
Published in:
IEEE Transactions on Visualization and Computer Graphics, Issue 2, 2020, ISSN 1077-2626
Publisher:
Institute of Electrical and Electronics Engineers
DOI:
10.1109/tvcg.2019.2934629
Author(s):
Francisco Merino-Casallo; Maria Jose Gomez-Benito; Silvia Hervas-Raluy; Jose Manuel Garcia-Aznar
Published in:
Cell Adhesion & Migration, 2022, ISSN 1933-6918
Publisher:
Landes Bioscience
DOI:
10.1080/19336918.2022.2055520
Author(s):
Paul Richmond, Robert Chisholm, Peter Heywood, Mozhgan Kabiri Chimeh, Matthew Leach
Published in:
Software: Practice and Experience, 2023, ISSN 1097-024X
Publisher:
Wiley Online Library
DOI:
10.1002/spe.3207
Author(s):
Juste-Lanas Y, Guerrero PE, Camacho-Gómez D, Hervás-Raluy S, García-Aznar JM, Gomez-Benito MJ.
Published in:
Journal of Biomechanical Engineering, 2021, ISSN 1528-8951
Publisher:
The American Society of Mechanical Engineers(ASME)
DOI:
10.1115/1.4053143
Author(s):
Alamán-Díez, P., Borau, C., Guerrero, P. E., Amaveda, H., Mora, M., Fraile, J. M., ... & Pérez, M. Á
Published in:
Biomacromolecules, 2023, ISSN 1526-4602
Publisher:
American Chemical Society
DOI:
10.1021/acs.biomac.3c00257
Author(s):
Camilla Scapicchio; Michela Gabelloni; Sara Maria Forte; Leonor Cerdá Alberich; Lorenzo Faggioni; Rita Borgheresi; Paola Erba; Fabiola Paiar; Luis Marti-Bonmati; Emanuele Neri
Published in:
European Radiology Experimental, Issue 5, 2021, ISSN 2509-9280
Publisher:
Springer Open
DOI:
10.1186/s41747-021-00214-4
Author(s):
Gonçalves, Inês G.; García-Aznar, José Manuel
Published in:
Computational and Structural Biotechnology Journal, 2023, ISSN 2001-0370
Publisher:
Elsevier
DOI:
10.1016/j.csbj.2023.01.044
Author(s):
Daniel Camacho-Gómez; José Manuel García-Aznar; María José Gómez-Benito
Published in:
Engineering with computers, 2022, ISSN 0177-0667
Publisher:
Springer Verlag
DOI:
10.1007/s00366-022-01654-1
Author(s):
Kondylakis, Haridimos; Ciarrocchi, Esther; Cerda-Alberich, Leonor; Chouvarda, Ioanna; Fromont, Lauren A.; Garcia-Aznar, Jose Manuel; Kalokyri, Varvara; Kosvyra, Alexandra; Walker, Dawn; Yang, Guang; Neri, Emanuele; The AI4HealthImaging Working Group on metadata models
Published in:
European Radiology Experimental, 2022, ISSN 2509-9280
Publisher:
Springer
DOI:
10.1186/s41747-022-00281-1
Author(s):
Gonçalves IG; Hormuth II DA; Prabhakaran S; Phillips CM; García-Aznar JM
Published in:
GigaByte, 2023, ISSN 2709-4715
Publisher:
BGI and Oxford University Press
DOI:
10.46471/gigabyte.77
Author(s):
Diego Sainz-DeMena; Wenfeng Ye; María Ángeles Pérez; José Manuel García-Aznar
Published in:
Engineering with Computers, 2022, ISSN 0177-0667
Publisher:
Springer Verlag
DOI:
10.1007/s00366-022-01667-w
Author(s):
Diego Sainz-DeMena; José Manuel García-Aznar; María Ángeles Pérez; Carlos Borau
Published in:
Applied Sciences, 2022, ISSN 2076-3417
Publisher:
MDPI
DOI:
10.3390/app122211557
Author(s):
A. Nieto; Jorge Escribano; Fabian Spill; José Manuel García-Aznar; M. J. Gómez-Benito
Published in:
Engineering Fracture Mechanics, Issue 1, 2020, Page(s) 106718, ISSN 0013-7944
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.engfracmech.2019.106718
Author(s):
Luis Marti-Bonmati; Dow-Mu Koh; Katrine Riklund; Maciej Bobowicz; Yiannis Roussakis; Joan C. Vilanova; Jurgen J. Fütterer; Jordi Rimola; Pedro Mallol; Gloria Ribas; Ana Miguel; Manolis Tsiknakis; Karim Lekadir; Gianna Tsakou
Published in:
Insights Into Imaging, 2022, ISSN 1869-4101
Publisher:
Springer Science and Business Media Deutschland GmbH
DOI:
10.1186/s13244-022-01220-9
Author(s):
Leonor Cerdá-Alberich; Jimena Solana; Pedro Mallol; Gloria Ribas; Miguel García-Junco; Angel Alberich-Bayarri; Luis Marti-Bonmati
Published in:
Insights into Imaging, 2023, ISSN 1869-4101
Publisher:
Springer Science and Business Media Deutschland GmbH
DOI:
10.1186/s13244-022-01355-9
Author(s):
Matías Fernández Patón; Leonor Cerdá Alberich; Cinta Sangüesa Nebot; Blanca Martínez de las Heras; Diana Veiga Canuto; Adela Cañete Nieto; Luis Martí-Bonmatí
Published in:
Journal of Digital Imaging, Issue 6, 2021, Page(s) 1134–1145, ISSN 0897-1889
Publisher:
Springer Verlag
DOI:
10.1007/s10278-021-00512-8
Author(s):
Francisco Merino-Casallo; Maria Jose Gomez-Benito; Ruben Martinez-Cantin; Jose Manuel Garcia-Aznar
Published in:
European Journal of Cell Biology, Issue 1, 2022, ISSN 1618-1298
Publisher:
Elsevier
DOI:
10.1016/j.ejcb.2022.151255
Author(s):
Luis Martí-Bonmatí, Ángel Alberich-Bayarri, Ruth Ladenstein, Ignacio Blanquer, J. Damian Segrelles, Leonor Cerdá-Alberich, Polyxeni Gkontra, Barbara Hero, J. M. García-Aznar, Daniel Keim, Wolfgang Jentner, Karine Seymour, Ana Jiménez-Pastor, Ismael González-Valverde, Blanca Martínez de las Heras, Samira Essiaf, Dawn Walker, Michel Rochette, Marian Bubak, Jordi Mestres, Marco Viceconti, Gra
Published in:
European Radiology Experimental, Issue 4/1, 2020, ISSN 2509-9280
Publisher:
European Radiology Experimental
DOI:
10.1186/s41747-020-00150-9
Author(s):
Giovanni Lucignani; Emanuele Neri
Published in:
Clinical and Translational Imaging, Issue 1, 2019, ISSN 2281-5872
Publisher:
Springer
DOI:
10.1007/s40336-019-00320-9
Author(s):
Bárbara de Melo Quintela, Silvia Hervas-Raluy, Jose Manuel Garcia-Aznar, Dawn Walker, Kenneth Y. Wertheim, Marco Viceconti,
Published in:
Journal of Theoretical Biology, 2022, ISSN 0022-5193
Publisher:
Academic Press
Author(s):
Diana Veiga-Canuto; Leonor Cerdà-Alberich; Ana Jiménez-Pastor; José Miguel Carot Sierra; Armando Gomis-Maya; Cinta Sangüesa-Nebot; Matías Fernández-Patón; Blanca Martínez de las Heras; Sabine Taschner-Mandl; Vanessa Düster; Ulrike Pötschger; Thorsten Simon; Emanuele Neri; Ángel Alberich-Bayarri; Adela Cañete; Barbara Hero; Ruth Ladenstein; Luis Martí-Bonmatí
Published in:
Cancers, Issue Volume 15; Issue 5, 2023, Page(s) 1622, ISSN 2072-6694
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/cancers15051622
Author(s):
Viceconti, Marco; Juarez, Miguel A.; Curreli, Cristina; Pennisi, Marzio; Russo, Giulia; Pappalardo, Francesco
Published in:
IEEE Journal of Biomedical and Health Informatics, Issue 3, 2019, ISSN 2168-2194
Publisher:
Institute of Electrical and Electronics Engineers Inc.
DOI:
10.1109/jbhi.2019.2949888
Author(s):
V. Varella, B de Melo Quintela, M. Kasztelnik, and M. Viceconti
Published in:
International Journal for Numerical Methods in Biomedical Engineering, 2022, ISSN 2040-7939
Publisher:
John Wiley & Sons Ltd.
DOI:
10.1002/cnm.3657
Author(s):
Italia, M.; Wertheim, K.Y.; Taschner-Mandl, S.; Walker, D.; Dercole, F.
Published in:
Cancers, 2023, ISSN 2072-6694
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/cancers15071986
Author(s):
Daniel Navajas; José Manuel Garcia-Aznar; Gabriel Beltran
Published in:
Journal of the Mechanical Behavior of Biomedical Materials, 2022, ISSN 1751-6161
Publisher:
Elsevier BV
DOI:
10.1016/j.jmbbm.2021.105043
Author(s):
Inês G. Gonçalves; José Manuel Garcia-Aznar
Published in:
PLoS Computational Biology, Issue 8, 2021, ISSN 1553-734X
Publisher:
Public Library of Science
DOI:
10.1371/journal.pcbi.1008764
Author(s):
Leonor Cerdá Alberich; Cinta Sangüesa Nebot; Angel Alberich-Bayarri; José Miguel Carot Sierra; Blanca Martínez de las Heras; Diana Veiga Canuto; Adela Cañete; Luis Martí-Bonmatí
Published in:
Cancers, Issue 3, 2020, Page(s) 3858, ISSN 2072-6694
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/cancers12123858
Author(s):
Silvia Hervas-Raluy; Barbara Wirthl; Pedro E. Guerrero; Gil Robalo Rei; Jonas Nitzler; Esther Coronado; Jaime Font de Mora Sainz; Bernhard A. Schrefler; Maria Jose Gomez-Benito; Jose Manuel Garcia-Aznar; Wolfgang A. Wall
Published in:
Computers in Biology and Medicine, 2023, ISSN 1879-0534
Publisher:
Elsevier
DOI:
10.1016/j.compbiomed.2023.106895
Author(s):
Marian Bubak; K. Czechowicz; Tomasz Gubała; D. R. Hose; Marek Kasztelnik; Maciej Malawski; Jan Meizner; Piotr Nowakowski; S. Wood
Published in:
Interface Focus, Issue 5, 2021, ISSN 2042-8898
Publisher:
Royal Society Publishing
DOI:
10.1098/rsfs.2020.0006
Author(s):
Haridimos Kondylakis; Varvara Kalokyri; Stelios Sfakianakis; Kostas Marias; Manolis Tsiknakis; Ana Jimenez-Pastor; Eduardo Camacho-Ramos; Ignacio Blanquer; J. Damian Segrelles; Sergio López-Huguet; Caroline Barelle; Magdalena Kogut-Czarkowska; Gianna Tsakou; Nikolaos Siopis; Zisis Sakellariou; Paschalis Bizopoulos; Vicky Drossou; Antonios Lalas; Konstantinos Votis; Pedro Mallol; Luis Marti-Bonmat
Published in:
European radiology experimental, Issue 3, 2023, ISSN 2509-9280
Publisher:
Springer Open
DOI:
10.1186/s41747-023-00336-x
Author(s):
V. Giménez-Alventosa; José Damián Segrelles; Germán Moltó; Mar Roca-Sogorb
Published in:
Methods of Information in Medicine, Issue 2, 2020, Page(s) e33-e45, ISSN 0026-1270
Publisher:
Schattauer
DOI:
10.1055/s-0040-1712460
Author(s):
Juri F. Buchmüller; Udo Schlegel; Eren Cakmak; Daniel A. Keim; Evanthia Dimara
Published in:
Computers & Graphics, Issue 1, 2021, ISSN 0097-8493
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.cag.2021.08.003
Author(s):
Udo Schlegel, Daniel A. Keim
Published in:
Workshop on Trust and Expertise in Visual Analytics (TREX) at IEEE Visualization Conference (VIS), 2021
Publisher:
Cornell University
DOI:
10.1109/trex53765.2021.00010
Author(s):
Udo Schlegel, Duy Vo Lam, Daniel A. Keim, Daniel Seebacher
Published in:
Advances in Interpretable Machine Learning and Artificial Intelligence (AIMLAI) at ECML/PKDD 2021, 2021
Publisher:
Cornell University
Author(s):
Hervas-Raluy, Silvia; Sainz de Mena, Diego; Gómez Benito, Mª José; García-Aznar, José Manuel
Published in:
Jornada De Jóvenes Investigadores E Investigadoras Del I3A, 2022
Publisher:
Jornada De Jóvenes Investigadores E Investigadoras Del I3A
DOI:
10.26754/jjii3a.20226993
Author(s):
Varella, Vinicius
Published in:
2023
Publisher:
University of Bolognia
DOI:
10.5281/zenodo.8025198
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