Project description
Green medicinal chemistry
The carbon–carbon bond forms the basic skeleton of an organic compound, and its synthesis is of paramount importance for the pharmaceutical industry. Formation of the carbon–carbon bond is catalysed through cross-coupling reactions by metals such as palladium. The environmental impact of these reactions urged scientists of the EU-funded CC-Coupler project to look for greener alternatives. To that end, they have generated a novel catalyst-based technology that is cost-effective and environmentally sustainable yet demonstrates high-performance organic synthesis. Implementation of this technology is expected to lead to the synthesis of new compounds for medicinal purposes.
Objective
Pharmaceutical industry needs environmentally cleaner processes. One of the most important family of chemical reaction is the formation of carbon-carbon bond by Pd mediated C-C coupling. It is estimated, that more than 50% of new drug synthesis will include at least one C-C coupling reactions. However, there are several issues regarding this reaction related to high environmental impact, complicated processes due to air-sensitive catalyst, post-processing, solvent issues, and catalyst recovery. We have developed a new integrated approach for carrying out C-C coupling reactions in an environmental benign and cost-effective way. Our CC-Coupler method targets to overcome all the issues regarding the reaction. Our aim is to commercialise the CC-Coupler as an integrated technology, providing an air-stable, highly performant catalyst with an adequate flow-chemistry device and parameter set optimised for the clients’ needs. In this Phase 1 project, as a first step, we shall carry out a feasibility assessment. The success of this project will promote the growth of our company and make a step towards cleaner pharmaceutical industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences basic medicine medicinal chemistry
- natural sciences chemical sciences catalysis
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1025 BUDAPEST
Hungary
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.