Project description
Better-informed therapy against thrombosis
Thrombosis – the development of blood clots in veins or arteries – is a dangerous condition that can lead to blocked blood flow and eventually to life-threatening emergencies such as heart attack. Venous ultrasounds or CT angiography scans are used to diagnose thrombosis, while platelet aggregation and function tests are employed to monitor the efficacy of antiplatelet therapy and to potentially identify the condition. The EU-funded Smart Clot project has developed a cutting-edge technology for monitoring coagulation and platelet function. It is automated and easy to use, providing both quantitative and qualitative multiparametric data. Implementation of the platform into routine screening will assist thrombosis treatment.
Objective
Today there is a big concern about cardiovascular diseases (CVD); because each year, it causes 3.9 million deaths in Europe and over 1.8 million deaths in the European Union. With almost 49 million people living with cardiovascular disease in the EU, these problems have a huge impact on public health and on health and economic resources, with a total cost of € 2.10 billion/year. Unfortunately, over the last 25 years the number of cardiovascular diseases cases has increased in Europe. The current medical devices monitor just platelet aggregation or coagulation providing inaccurate estimations and in consequence observing insufficient therapy in thrombosis treatment or excessive therapy dosage in bleeding cases in individual patients. In response, we at SEDICIDODICI have developed, SMART CLOT, a cutting-edge technology for the combined evaluation of coagulation and platelet function for monitoring i) haemostasis (process which causes bleeding to stop, keeping the blood within a damaged blood vessel) as diagnosis tool and ii) antithrombotic treatment to control patients with diseases such as cardiovascular diseases, hypertension, thrombosis, diabetes, pulmonary embolism. It is a user-friendly, automated and real-time platform that provides qualitative/quantitative information based on an instrument and an array of multifunctional flow cartridges designed to interrogate specific pathways of both coagulation and platelet activation under relevant arterial and venous flow conditions. Before reaching market maturity we need in Phase 1 to run a Feasibility Study that helps us organise technical, commercial and financial plan of the project. Finally, SMART CLOT will bring an effective platform for the diagnosis and antithrombotic treatment. SEDICIDODICI will concentrate on the growth of SMART CLOT and in 5 years from launch we expect to earn € 22.3 million in profits, 24 new people and a ROI of 6.08 per euro invested.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- medical and health sciences clinical medicine angiology vascular diseases
- medical and health sciences clinical medicine endocrinology diabetes
- natural sciences computer and information sciences software software development
- medical and health sciences clinical medicine cardiology cardiovascular diseases
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
33170 PORDENONE
Italy
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.