Project description
Development of bio cellulose-based wound dressing material
Traumatic burn injuries result in considerable morbidity and mortality, requiring long hospitalisation, rehabilitation, and costly wound and scar treatment. Traditional wound dressing materials are often associated with life-threatening infections, especially in the case of significant burn injuries. The EU-funded BC SKIN project is working on the innovative production of bacterial cellulose for the creation of dressing material for burn wound treatment, opening the possibility for the global transition from conventional to biomaterial-based wound dressings with better healing and antibacterial properties that reduce treatment time. The BC SKIN product can be used for I-II degree burns, cuts and other kinds of wounds. The project team has developed application guidelines, product certification and packaging requirements, and has identified the best antibacterial additive for fast and efficient wound healing.
Objective
Burn injury is a common type of traumatic injury, causing considerable morbidity and mortality. Moreover, burns are also among the most expensive traumatic injuries, because of long hospitalization and rehabilitation, and costly wound and scar treatment. Worldwide, an estimated 6 million patients seek medical help for burns annually, but the majority are treated in outpatient clinics. According to World Health Organisation, estimated burn management costs in 2017 were 10.5 billion EUR. The removal of traditional dressing material can adhere to desiccated wound surfaces and induce trauma followed by life-threatening infectious contamination. The treatment time is long and complicated. Recovery process of skin, that often-become life threatening, if complicated by infectious contamination, is always highly dangerous in case of large burn injuries. Project team has conducted experimental research and patented an efficient nanostructured cellulose-producing strain. It has been characterized by increased rate of Bacterial Cellulose (BC) production, also by high cellulose yield from the consumed Csubstrate. Both parameters, also facilities of application of a cheap raw material, for bacteria growth and BC synthesis is an essential advantage of the strain to increase cellulose production per unit of time and space (surface area of fermentation vessels) and to reduce expenses associated with cellulose production. In general, the main innovation of the process is due to the high productivity of BC process achieved through the use of a unique patented producer-strains and bio-technological approaches, as well the modification of BC with bio-active substances with custom target activity. Thanks to the unique properties of BC material, project aims to introduce BC SKIN product within the application in medicine industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
- medical and health sciencesclinical medicinedermatology
- medical and health sciencesclinical medicineclinical microbiology
- medical and health scienceshealth scienceshealth care services
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Programme(s)
Funding Scheme
SME-1 - SME instrument phase 1Coordinator
1024 RIGA
Latvia
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.