A novel optical approach for studying and treating the brain
Currently, optogenetics is employed to measure neuronal activity and study brain function. However, it requires genetically encoded proteins, limiting its translational applicability. The EU-funded NanoBRIGHT project is developing a novel technology based on the interaction of light with metallic nanostructures which will increase the range of physiological phenomena that can be controlled and monitored by light in vivo. This includes the modulation of the blood–brain barrier's permeability to allow pharmacological targeting of the brain, as well as the possibility to identify tumorigenic tissue without the need of a biopsy. The new approach will advance the treatment of pathological conditions including brain tumours, epilepsy and traumatic brain injuries.
Fields of science
Call for proposal
See other projects for this call