Deliverables Documents, reports (25) Toolbox of MNPs V3.0/Public Public report on final round of MNPs toolbox with magnetic heating profiles complementary to the Topt of the enzymes Report MNP general toxicity Report on MNPs toxicity Third round of project newsletters Report on the preparation of the third round of Newsletters Final report MNP general toxicity Final report on MNPs toxicity Monoenzyme hybrid composite toolbox/Public Public report on the proof of concept of hybrid composites bearing one enzyme immobilized on MNPs entrapped into 3D-porous microparticles Hybrid composites stability at operational conditions for sugar biotransformations Report on hybrids stability for hightemperature sugar biotransformations under extensive AMF use Cell free system for enzyme synthesis/immobilization_Public Public report on cellfree system to synthesize and immobilized enzyme variants in onepot Second round of project newsletters Report on the preparation of the second round of Newsletters Industrial Partnering event Standalone event with potencial industrial stakeholders Assay for metals ion leakage detection Assay to detect metal ions leakage from MNPs Hybrid stability at AMF operational conditions for THIQ production Report on the hybrid composites stability for THIQ production under extensive AMF use Leaflets and rollers Report on the production of Leaflets and rollers AMF features to tune enzyme activity/Public Public report on optimal AMF settings for tuning ADHT activity by reaching different local temperatures using the selected MNPs at D1.1 Hybrid composites stability and toxicity Stability of the different hybrid composites under extensive AMF use and toxicity tests Enzyme@MNP stability and toxicity Stability of the different engineered enzymes immobilized on MNPs under extensive AMF use and toxicity tests Hotzyme website, logo and social media accounts Report on Hotzyme website, logo and social media accounts (i.e: Tweeter, Facebook and LinkedIn) Functionalized MNP toolbox MNPs with complementary chemistry to immobilize the engineered enzymes AMF features to tune heat transfer V2.0/Public Public final report on features that allow tuning MNPs heat transfer Final round of project newsletters Report on the preparation of the final round of Newsletters Multienzyme hybrid composite toolbox V2.0_Public Public report on final multienzyme hybrid composite toolbox simultaneously or sequentially activated under certain AMF settings First round of project newsletters Report on the preparation of the first round of Newsletters Thermal nanoactuated synthesis of α-glucosyl-2-glycerate_Public Public report on new AMFtuned process window for hightemperature synthesis of glucosyl2glycerate Aminoacid cluster toolbox/Public Public report on aminoacid cluster toolbox to allow enzyme orientation through target regions Thermal nanoactuated sucrose conversion wo fructose decomposition_Public Public report on new AMFtuned process window for hightemperature conversion of sucrose without fructose breakdown His-tagged enzymes variants His-tagged variants to immobilized enzyme through N- or C-terminus Open Research Data Pilot (1) Data Management Plan Report on Data Management Plan Publications Peer reviewed articles (21) Reproducibility and scalability of magnetic nanoheater synthesis Author(s): Ovejero, Jesus; Gallo-Cordova, Alvaro; Roca, Alejandro G.; Morales, M.P.; Veintimillas-Verdaguer, Sabino Published in: Nanomaterials, Issue 20794991, 2021, ISSN 2079-4991 Publisher: MDPI AG DOI: 10.3390/nano11082059 The Yin and Yang of epigenetics in the field of nanoparticles Author(s): Elettra Musolino; Christina Pagiatakis; Simone Serio; Marina Borgese; Federica Gamberoni; Rosalba Gornati; Giovanni Bernardini; Roberto Papait Published in: Nanoscale Advances, Issue 25160230, 2022, ISSN 2516-0230 Publisher: Royal Society of Chemistry DOI: 10.1039/d1na00682g Mixing iron oxide nanoparticles with different shape and size for tunable magneto-heating performance Author(s): Jesus G. Ovejero, Federico Spizzo, M. Puerto Morales, Lucia Del Bianco Published in: Nanoscale, Issue 13/11, 2021, Page(s) 5714-5729, ISSN 2040-3364 Publisher: Royal Society of Chemistry DOI: 10.1039/d0nr09121a How size, shape and assembly of magnetic nanoparticles give rise to different hyperthermia scenarios Author(s): Gavilan, H.; Simeonidis, K.; Myrovali, E.; Mazarío, E.; Chubykalo-Fesenko, O.; Chantrell, R.; Balcells, Ll.; Angelakeris, M; Morales, M.P.; Serantes, D. Published in: Nanoscale, Issue 20403364, 2021, ISSN 2040-3364 Publisher: Royal Society of Chemistry DOI: 10.1039/d1nr03484g Real-Time Intracellular Temperature Imaging Using Lanthanide-Bearing Polymeric Micelles. Author(s): Raquel Moreno-Loshuertos; Ángel Millán; P. Tellez; Patricio Fernández-Silva; Luis Martínez-Lostao; Carlos D. S. Brites; Rafael Piñol; Albano N. Carneiro Neto; A. Martinez; Yuanyu Gu; Justyna Zeler; Justyna Zeler; Thiago Silva; Thiago Silva; Ana Isabel Gallego; Luís D. Carlos Published in: Nano Letters, Issue 3, 2020, ISSN 1530-6984 Publisher: American Chemical Society DOI: 10.1021/acs.nanolett.0c02163 Tailoring the Magnetic and Structural Properties of Manganese/Zinc Doped Iron Oxide Nanoparticles through Microwaves-Assisted Polyol Synthesis Author(s): Porru, Margherita; Morales, Maria del Puerto; Gallo-Cordova, Alvaro; Espinosa, Ana; Moros, Maria; Brero, Francesca; Mariani, Manuel; Lascialfari, Alessandro; G. Ovejero, Jesus Published in: Nanomaterials, Issue 20794991, 2022, ISSN 2079-4991 Publisher: MDPI DOI: 10.3390/nano12193304 Magnetic hyperthermia with ε-Fe 2 O 3 nanoparticles Author(s): Yuanyu Gu, Marie Yoshikiyo, Asuka Namai, Debora Bonvin, Abelardo Martinez, Rafael Piñol, Pedro Téllez, Nuno J. O. Silva, Fredrik Ahrentorp, Christer Johansson, Joaquín Marco-Brualla, Raquel Moreno-Loshuertos, Patricio Fernández-Silva, Yuwen Cui, Shin-ichi Ohkoshi, Angel Millán Published in: RSC Advances, Issue 10/48, 2020, Page(s) 28786-28797, ISSN 2046-2069 Publisher: Royal Society of Chemistry DOI: 10.1039/d0ra04361c Self-sufficient asymmetric reduction of β-ketoesters catalysed by a novel and robust thermophilic alcohol dehydrogenase co-immobilised with NADH Author(s): Alejandro H. Orrego, Daniel Andrés-Sanz, Susana Velasco-Lozano, Mercedes Sanchez-Costa, José Berenguer, José M. Guisan, Javier Rocha-Martin, Fernando López-Gallego Published in: Catalysis Science & Technology, 2021, ISSN 2044-4753 Publisher: Royal Society of Chemistry DOI: 10.1039/d1cy00268f Photonic and magnetic materials for on-demand local drug delivery Author(s): Armenia, Ilaria; Cuestas Ayllon, Carlos; Torres Herrero, Beatriz; Bussolari, Francesca; Alfranca, Gabriel; Grazú, Valeria; Martínez de la Fuente, Jesús Published in: Advanced Drug Delivery Reviews, Issue 0169409X, 2022, ISSN 0169-409X Publisher: Elsevier BV DOI: 10.1016/j.addr.2022.114584 Antimicrobial Activity of Nanoconjugated Glycopeptide Antibiotics and Their Effect on Staphylococcus aureus Biofilm Author(s): Berini, Francesca; Orlandi, Viviana Teresa; Gamberoni, Federica; Martegani, Eleonora; Armenia, Ilaria; Gornati, Rosalba; Bernardini, Giovanni; Marinelli, Flavia Published in: Frontiers in Microbiology, Issue 1664302X, 2021, ISSN 1664-302X Publisher: Frontiers Media DOI: 10.3389/fmicb.2021.657431 Continuous production of magnetic iron oxide nanocrystals by oxidative precipitation Author(s): T. Asimakidou, A. Makridis, S. Veintemillas-Verdaguer, M.P. Morales, I. Kellartzis, M. Mitrakas, G. Vourlias, M. Angelakeris, K. Simeonidis Published in: Chemical Engineering Journal, Issue 393, 2020, Page(s) 124593, ISSN 1385-8947 Publisher: Elsevier BV DOI: 10.1016/j.cej.2020.124593 Iron nanoparticle bio-interactions evaluated in Xenopus laevis embryos, a model for studying the safety of ingested nanoparticles Author(s): Patrizia Bonfanti, Anita Colombo, Melissa Saibene, Luisa Fiandra, Ilaria Armenia, Federica Gamberoni, Rosalba Gornati, Giovanni Bernardini, Paride Mantecca Published in: Nanotoxicology, Issue 14/2, 2020, Page(s) 196-213, ISSN 1743-5390 Publisher: Informa Healthcare DOI: 10.1080/17435390.2019.1685695 Stabilization of b-Glucuronidase by Immobilization in Magnetic-Silica Hybrid Supports Author(s): Sonali Correa, Magdalena Ripoll, Erienne Jackson, Valeria Grazú, Lorena Betancor Published in: Catalysts, Issue 10/6, 2020, Page(s) 669, ISSN 2073-4344 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/catal10060669 The Thermodynamics of Medial Vascular Calcification Author(s): Ángel Millán, Peter Lanzer, Víctor Sorribas Published in: Frontiers in cell and developmental biology, 2021, ISSN 2296-634X Publisher: Frontiers Media S.A. DOI: 10.3389/fcell.2021.633465 Efficient Brownian oscillators and nanoheaters based on gallium-doped ε-Fe2O3 Author(s): Yuanyu Gu, Nuno J. O. Silva, Marie Yoshikiyo, Asuka Namai, Rafael Piñol, Guillaume Maurin-Pasturel, Yuwen Cui, Shin-ichi Ohkoshi, Angel Millán ORCID, Abelardo Martínez Published in: Chemical Communications, 2021, ISSN 1359-7345 Publisher: Royal Society of Chemistry DOI: 10.1039/d0cc07309a High-Dose Exposure to Polymer-Coated Iron Oxide Nanoparticles Elicits Autophagy-Dependent Ferroptosis in Susceptible Cancer Cells Author(s): Thanpisit Lomphithak, Selin Helvacioglu, Ilaria Armenia, Sandeep Keshavan, Jesus g. Ovejero, Giovanni Baldi, Costanza Ravagli, Valeria Grazu, Bengt Fadeel Published in: Nanomaterials, Issue 13(11), 2023, Page(s) 1719, ISSN 2079-4991 Publisher: MDPI DOI: 10.3390/nano13111719 Nanoantibiotics to fight multidrug resistant infections by Gram-positive bacteria: hope or reality? Author(s): Berini, Francesca; Orlandi, Viviana; Gornati, Rosalba; Bernardini, Giovanni; Marinelli, Flavia Published in: Biotechnology Advances, Issue 07349750, 2022, ISSN 0734-9750 Publisher: Elsevier BV DOI: 10.1016/j.biotechadv.2022.107948 Nanoparticles for Magnetic Heating: When Two (or More) Is Better Than One Author(s): Jesus G. Ovejero; Federico Spizzo; M. Puerto Morales; Lucia Del Bianco Published in: Materials, Issue 20782489, 2021, ISSN 2078-2489 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ma14216416 Selective Magnetic Nanoheating: Combining Iron Oxide Nanoparticles for Multi-Hot-Spot Induction and Sequential Regulation. Author(s): Jesus G. Ovejero; Ilaria Armenia; David Serantes; Sabino Veintemillas-Verdaguer; Nicoll Zeballos; Fernando López-Gallego; Cordula Grüttner; Jesús M. de la Fuente; María del Puerto Morales; Valeria Grazú Published in: Nano Letters, Issue 15306984, 2021, ISSN 1530-6984 Publisher: American Chemical Society DOI: 10.1021/acs.nanolett.1c02178 Energetics of the Glycosyl Transfer Reactions of Sucrose Phosphorylase Author(s): Anisha Vyas, Bernd Nidetzky Published in: Biochemistry, 2023, ISSN 0006-2960 Publisher: American Chemical Society DOI: 10.1021/acs.biochem.3c00080 Understanding MNPs Behaviour in Response to AMF in Biological Milieus and the Effects at the Cellular Level: Implications for a Rational Design That Drives Magnetic Hyperthermia Therapy toward Clinical Implementation. Author(s): David Egea-Benavente; Jesus G. Ovejero; Jesus G. Ovejero; María del Puerto Morales; Domingo F. Barber Published in: Cancers, Vol 13, Iss 4583, p 4583 (2021), Issue 20726694, 2021, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers13184583 Book chapters (1) Magnetic Iron Oxide Colloids for Environmental Applications Author(s): Alvaro Gallo-Cordova, Daniela Almeida Streitwieser, María del Puerto Morales, Jesús G. Ovejero Published in: Colloids - Types, Preparation and Applications [Working Title], 2021 Publisher: IntechOpen DOI: 10.5772/intechopen.95351 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available