Exploring the role of GPCR expression diversity in receptor physiology and drug response

Project Information

GPCR Transcriptomics

Grant agreement ID: 832620

DOI

10.3030/832620

Project closed

EC signature date 18 March 2019

Start date 1 May 2019

End date 30 April 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 212 933,76

EU contribution

€ 212 933,76

Coordinated by

UNITED KINGDOM RESEARCH AND INNOVATION
United Kingdom

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (2)

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

Author(s): Bas Brouwers, Edson Mendes de Oliveira, Maria Marti-Solano, Fabiola B.F. Monteiro, Suli-Anne Laurin, Julia M. Keogh, Elana Henning, Rebecca Bounds, Carole A. Daly, Shane Houston, Vikram Ayinampudi, Natalia Wasiluk, David Clarke, Bianca Plouffe, Michel Bouvier, M. Madan Babu, I. Sadaf Farooqi, Jacek Mokrosiński
Published in: Cell Reports, Issue 34/12, 2021, Page(s) 108862, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.108862

Combinatorial expression of GPCR isoforms affects signalling and drug responses

Author(s): Maria Marti-Solano, Stephanie E. Crilly, Duccio Malinverni, Christian Munk, Matthew Harris, Abigail Pearce, Tezz Quon, Amanda E. Mackenzie, Xusheng Wang, Junmin Peng, Andrew B. Tobin, Graham Ladds, Graeme Milligan, David E. Gloriam, Manojkumar A. Puthenveedu, M. Madan Babu
Published in: Nature, Issue 587/7835, 2020, Page(s) 650-656, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2888-2