Unravelling the secretion machinery for virulence factors in apicomplexan parasites

Project Information

KissAndSpitRhoptry

Grant agreement ID: 833309

DOI

10.3030/833309

EC signature date 12 August 2019

Start date 1 October 2020

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 496 210,00

EU contribution

€ 2 496 210,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

An Alveolata secretory machinery adapted to parasite host cell invasion

Author(s): Eleonora Aquilini, Marta Mendonça Cova, Shrawan Kumar Mageswaran, Nicolas Dos Santos Pacheco, Daniela Sparvoli, Diana Marcela Penarete-Vargas, Rania Najm, Arnault Graindorge, Catherine Suarez, Marjorie Maynadier, Laurence Berry-Sterkers, Serge Urbach, Pilar Ruga Fahy, Amandine N Guérin, Boris Striepen, Jean-François Dubremetz, Yi-Wei Chang, Aaron P Turkewitz, Maryse Lebrun
Published in: Nature Microbiology, 2021, ISSN 2058-5276
Publisher: Nature Portfolio
DOI: 10.1038/s41564-020-00854-z

Rhoptry secretion system structure and priming in Plasmodium falciparum revealed using in situ cryo-electron tomography

Author(s): Martinez M, Chen WD, Cova MM, Molnár P, Mageswaran SK, Guérin A, John ARO, Lebrun M, Chang YW.
Published in: Nature Microbiology, 2022, ISSN 2058-5276
Publisher: Nature porfolio
DOI: 10.1038/s41564-022-01171-3

In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems

Author(s): Mageswaran SK, Guérin A, Theveny LM, Chen WD, Martinez M, Lebrun M, Striepen B, Chang YW.
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-25309-9

Unraveling the Elusive Rhoptry Exocytic Mechanism of Apicomplexa

Author(s): Daniela Sparvoli, Maryse Lebrun
Published in: Trends in Parasitology, 2021, ISSN 1471-4922
Publisher: Elsevier BV
DOI: 10.1016/j.pt.2021.04.011

How Apicomplexa Parasites Secrete and Build Their Invasion Machinery.

Author(s): Cova MM, Lamarque MH, Lebrun M.
Published in: Annual Review of Microbiology, 2022, ISSN 0066-4227
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-micro-041320-021425

An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma.

Author(s): Daniela Sparvoli; Jason Delabre; Diana Marcela Penarete‐Vargas; Shrawan Kumar Mageswaran; Lev M Tsypin; Justine Heckendorn; Liam Theveny; Marjorie Maynadier; Marta Mendonça Cova; Laurence Berry‐Sterkers; Amandine Guérin; Jean‐François Dubremetz; Serge Urbach; Boris Striepen; Aaron P Turkewitz; Yi‐Wei Chang; Maryse Lebrun
Published in: The EMBO Journal, Issue 1, 2022, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2022111158