Inhibiting parasitism of root-knot nematodes to prevent crop disease
Certain species of microscopic nematodes (roundworms) are parasitic to plants. Infestations of root-knot nematodes can be particularly destructive to a wide range of crop plants. Therefore, determining the agent that triggers their parasitic nature could lead to its inhibition and prevent crop loss. The EU-funded Mi-DOG project will investigate the genomic mechanism that causes the plant-parasitic nematode Meloidogyne incognita to infest plant roots, bringing about disease. Using knowledge of the non-coding DNA sequence of the nematode’s dorsal gland promoter, the project will identify the associated protein complex or “reader” that is responsible for plant parasitism using advanced CRISPR-mediated (clustered regularly interspaced short palindromic repeats) methodologies.
Fields of science
Funding SchemeMSCA-IF-EF-CAR - CAR – Career Restart panel
CB2 1TN Cambridge