Identifying how Evolution exploits physical properties of tissues to generate the complexity and diversity of Life

Project Information

EVOMORPHYS

Grant agreement ID: 834068

DOI

10.3030/834068

Project closed

EC signature date 8 May 2019

Start date 1 August 2019

End date 31 January 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 070,00

EU contribution

€ 2 499 070,00

Coordinated by

UNIVERSITE DE GENEVE
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (15)

In vivo sonic hedgehog pathway antagonism temporarily results in ancestral proto-feather-like structures in the chicken

Author(s): Rory L. Cooper, Michel C. Milinkovitch
Published in: PLOS Biology, Issue 23, 2025, Page(s) e3003061, ISSN 1545-7885
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3003061

Cell-biology effective interpretation of the Ising model describing skin color patterning

Author(s): Muhamet Ibrahimi, Szabolcs Zakany, Michel C. Milinkovitch
Published in: Physical Review Research, Issue 7, 2025, ISSN 2643-1564
Publisher: American Physical Society (APS)
DOI: 10.1103/physrevresearch.7.023093

Protocol for the rapid intravenous in ovo injection of developing amniote embryos

Author(s): Rory L. Cooper, Gabriel Santos-Duran, Michel C. Milinkovitch
Published in: STAR Protocols, 2023, ISSN 2666-1667
Publisher: Cell Press
DOI: 10.1016/j.xpro.2023.102324

Mechanical positional information guides the self-organized development of a polygonal network of creases in the skin of mammalian noses

Author(s): Paule Dagenais, Ebrahim Jahanbakhsh, Aurélien Capitan, Hélène Jammes, Karine Reynaud, Camino De Juan Romero, Victor Borrell, Michel.C. Milinkovitch
Published in: Current Biology, Issue 34, 2024, Page(s) 5197-5212.e4, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2024.09.055

Coupling Chemotaxis and Growth Poromechanics for the Modelling of Feather Primordia Patterning

Author(s): Nicolás A. Barnafi, Luis Miguel De Oliveira Vilaca, Michel C. Milinkovitch, and Ricardo Ruiz-Baier
Published in: mathematics, 2022, ISSN 2227-7390
Publisher: MDPI
DOI: 10.3390/math10214096

The Unreasonable Effectiveness of Reaction Diffusion in Vertebrate Skin Color Patterning

Author(s): Michel C. Milinkovitch, Ebrahim Jahanbakhsh, Szabolcs Zakany
Published in: Annual Review of Cell and Developmental Biology, 2023, ISSN 1081-0706
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-cellbio-120319-024414

Exacerbated sonic hedgehog signalling promotes a transition from chemical pre-patterning of chicken reticulate scales to mechanical skin folding

Author(s): Rory L. Cooper, Ebrahim Jahanbakhsh, Gabriel N. Santos Durán, Michel C. Milinkovitch
Published in: Open Biology, Issue 15, 2025, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.240342

High-resolution confocal and light-sheet imaging of collagen 3D network architecture in very large samples

Author(s): Grigorii Timin, Michel C. Milinkovitch
Published in: iScience, 2023, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2023.106452

Reaction-diffusion in a growing 3D domain of skin scales generates a discrete cellular automaton

Author(s): Fofonjka A., Milinkovitch M. C.
Published in: Nature Communications, Issue 12, 01 Apr 2021, 2021, Page(s) 2433, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22525-1

Modeling convergent scale-by-scale skin color patterning in multiple species of lizards

Author(s): Ebrahim Jahanbakhsh, Michel C. Milinkovitch
Published in: Current Biology, 2022, ISSN 1879-0445
Publisher: Cell Press
DOI: 10.1016/j.cub.2022.10.044

Lizard Skin Patterns and the Ising Model

Author(s): Zakany S, Smirnov S, Milinkovitch M. C.
Published in: Physical Review Letters, Issue 128, 27 January 2022, 2022, Page(s) 048102, ISSN 0031-9007
Publisher: American Physical Society
DOI: 10.1103/physrevlett.128.048102

Chemical and mechanical patterning of tortoise skin scales occur in different regions of the head

Author(s): Rory L. Cooper, Ebrahim Jahanbakhsh, Michel C. Milinkovitch
Published in: iScience, Issue 28, 2026, Page(s) 112684, ISSN 2589-0042
Publisher: Elsevier BV
DOI: 10.1016/j.isci.2025.112684

Simple Reaction-Diffusion Modeling Predicts Inconspicuous Neighborhood-Dependent Color Subclustering of Lizard Scales

Author(s): Szabolcs Zakany, Michel C. Milinkovitch
Published in: PHYSICAL REVIEW X, 2023, ISSN 2160-3308
Publisher: American Physical Society
DOI: 10.1103/physrevx.13.041011

Self-organized patterning of crocodile head scales by compressive folding

Author(s): Gabriel N. Santos-Durán, Rory L. Cooper, Ebrahim Jahanbakhsh, Grigorii Timin, Michel C. Milinkovitch
Published in: Nature, Issue 637, 2025, Page(s) 375-383, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-08268-1

Transient agonism of the sonic hedgehog pathway triggers a permanent transition of skin appendage fate in the chicken embryo

Author(s): Rory L. Cooper, Michel C. Milinkovitch
Published in: Science Advances, 2023, ISSN 2375-2548
Publisher: AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/sciadv.adg9619