The mammalian body plan blueprint, an in vitro approach

Project Information

MiniEmbryoBlueprint

Grant agreement ID: 834580

DOI 10.3030/834580

EC signature date 30 April 2019

Start date 1 October 2019

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 480 300,00

EU contribution € 2 480 300,00

Coordinated by

UNIVERSIDAD POMPEU FABRA
Spain

Publications

Peer reviewed articles (9)

Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids

Author(s): Ali Hashmi, Sham Tlili, Pierre Perrin, Molly Lowndes, Hanna Peradziryi, Joshua M Brickman, Alfonso Martínez Arias, Pierre-François Lenne
Published in: eLife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.59371

Gastruloid Development Competence Discriminates Different States of Pluripotency

Author(s): Cermola F D'Aniello C Tatè R De Cesare D Alfonso Martinez Arias Minchiotti G 1Patriarca EJ
Published in: Stem Cell Reports, 2021, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2020.12.013

Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering

Author(s): Alfonso Martinez Arias Yusuke Marikawa Naomi Moris
Published in: Developmental Biology, 2022, ISSN 0012-1606
Publisher: Academic Press
DOI: 10.1016/j.ydbio.2022.05.002

An ethical framework for human embryology with embryo models

Author(s): Nicolas C Rivron Alfonso Martinez Arias Martin F Pera Naomi Moris Hafez Ismaili M'hamdi
Published in: Cell, 2023, ISSN 2228-5806
Publisher: Royan Institute
DOI: 10.1016/j.cell.2023.07.028

Pluripotent stem cell models of early mammalian development.

Author(s): Naomi Moris; Alfonso Martinez Arias; Peter Baillie-Benson
Published in: Current Opinions in Cell Biology, Issue 1, 2020, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.17863/cam.53248

The cell in the age of the genomic revolution: Cell Regulatory Networks

Author(s): Nicole Gorfinkiel and Alfonso Martinez Arias
Published in: Cells and Development, 2021, ISSN 2667-2901
Publisher: Elsevier
DOI: 10.1016/j.cdev.2021.203720

Reconstituting human somitogenesis in vitro

Author(s): Yoshihiro Yamanaka Sofiane Hamidi Kumiko Yoshioka-Kobayashi Sirajam Munira Kazunori Sunadome Yi Zhang Yuzuru Kurokawa Rolf Ericsson Ai Mieda Jamie L Thompson Janet Kerwin Steven Lisgo Takuya Yamamoto Naomi Moris Alfonso Martinez Arias Taro Tsujimura Cantas Alev
Published in: Nature, 2023, ISSN 1476-4687
Publisher: Springer
DOI: 10.1038/s41586-022-05649-2

Establishment of the vertebrate body plan: Rethinking gastrulation through stem cell models of early embryogenesis

Author(s): Benjamin Steventon Laura Busby Alfonso Martinez Arias
Published in: Developmental Cell, 2021, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2021.08.012

Experimental embryology of gastrulation: pluripotent stem cells as a new model system

Author(s): Naomi Moris, Alfonso Martinez Arias, Benjamin Steventon
Published in: Current Opinion in Genetics & Development, Issue 64, 2020, Page(s) 78-83, ISSN 0959-437X
Publisher: Elsevier BV
DOI: 10.1016/j.gde.2020.05.031