Chronotype, health and family: The role of biology, socio- and natural environment and their interaction

Project Information

CHRONO

Grant agreement ID: 835079

DOI

10.3030/835079

Project closed

EC signature date 25 July 2019

Start date 1 November 2019

End date 31 October 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 811,00

EU contribution

€ 2 499 811,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (40)

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

Author(s): Mathieson, Iain; Day, Felix R; Barban, Nicola; Tropf, Felix C; Brazel, David M; EQTLGen Consortium; BIOS Consortium; Vaez, Ahmad; Van Zuydam, Natalie; Bitarello, Bárbara D; Gardner, Eugene J; Akimova, Evelina T; Azad, Ajuna; Bergmann, Sven; Bielak, Lawrence F; Boomsma, Dorret I; Bosak, Kristina; Brumat, Marco; Buring, Julie E; Cesarini, David; Chasman, Daniel I; Chavarro, Jorge E; Cocca, Massimil
Published in: Mathieson , I , Day , F R , Barban , N , Tropf , F C , Brazel , D M , van Heemst , D , Vaez , A , van Zuydam , N , Bitarello , B D , Gardner , E J , Akimova , E T , Azad , A , Bergmann , S , Bielak , L F , Boomsma , D I , Bosak , K , Brumat , M , Buring , J E , Cesarini , D , Chasman , D I , Chavarro , J E , Cocca , M , Concas , M P , Davey Smith , G , Davies , G , Deary , I J , Esko , T , Faul ,, Issue 2, 2023, Page(s) 790-801, ISSN 2397-3374
Publisher: Nature
DOI: 10.1038/s41562-023-01528-6

The Total Effect of Social Origins on Educational Attainment: Meta-analysis of Sibling Correlations From 18 Countries

Author(s): Lewis R. Anderson, Patrick Präg, Evelina T. Akimova, Christiaan Monden
Published in: Demography, Issue 61, 2024, Page(s) 1637-1666, ISSN 0070-3370
Publisher: Population Association of America
DOI: 10.1215/00703370-11579806

Quantifying impacts of the COVID-19 pandemic through life-expectancy losses: a population-level study of 29 countries.

Author(s): José Manuel Aburto; Jonas Schöley; Ilya Kashnitsky; Luyin Zhang; Charles Rahal; Trifon I. Missov; Melinda Mills; Jennifer Beam Dowd; Ridhi Kashyap
Published in: International Journal of Epidemiology, Issue 2, 2021, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyab207

Night shift work and sleep duration among middle and older age adults: The role of individual, social, and environmental moderators

Author(s): Xuejie Ding, Evelina T. Akimova, Bo Zhao, Melinda C. Mills
Published in: Social Science & Medicine, Issue 384, 2025, Page(s) 118443, ISSN 0277-9536
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.socscimed.2025.118443

Socio-economic status is a social construct with heritable components and genetic consequences

Author(s): Abdel Abdellaoui, Hilary C. Martin, Martin Kolk, Adam Rutherford, Michael Muthukrishna, Felix C. Tropf, Melinda C. Mills, Brendan P. Zietsch, Karin J. H. Verweij, Peter M. Visscher
Published in: Nature Human Behaviour, Issue 9, 2025, Page(s) 864-876, ISSN 2397-3374
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41562-025-02150-4

Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank

Author(s): Evelina T. Akimova, Tobias Wolfram, Xuejie Ding, Felix C. Tropf, Melinda C. Mills
Published in: Nature Human Behaviour, Issue 9, 2025, Page(s) 391-405, ISSN 2397-3374
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41562-024-02076-3

Within-sibship GWAS of 25 phenotypes improve estimates of direct genetic effects

Author(s): Howe, L.J et al, M.C. Mills
Published in: Nature Genetics, 2022, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-022-01062-7

COVID-19 vaccine hesitancy: the five Cs to tackle behavioural and sociodemographic factors

Author(s): Razai, M.S. et al., M.C.Mills
Published in: Journal of the Royal Society of Medicine, 2021, ISSN 0141-0768
Publisher: Royal Society of Medicine
DOI: 10.1177/01410768211018951

Factors affecting adherence to non-pharmaceutical interventions for COVID-19 infections in the first year of the pandemic in the UK

Author(s): Ding, X; Brazel, DM; Mills, MC
Published in: BMJ Open, 2021, Page(s) e054200, ISSN 0002-9297
Publisher: University of Chicago Press
DOI: 10.1136/bmjopen-2021-054200

Nowcasting daily population displacement in Ukraine through social media advertising data

Author(s): Leasure, DR; Kashyap, R; Rampazzo, F; Dooley, CA; Elbers, B; Bondarenko, M; Verhagen, M; Frey, A; Yan, J; Akimova, ET; Fatehkia, M; Trigwell, R; Tatem, AJ; Weber, I; Mills, MC
Published in: Crossref, Issue 1, 2023, Page(s) 231-254, ISSN 0098-7921
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/padr.12558

Gender, nonstandard schedules, and partnership quality in the UK: Exploring heterogeneous effects through a quasi-experiment.

Author(s): Riley Taiji
Published in: Social Science Research, Issue 1, 2019, ISSN 0049-089X
Publisher: Academic Press
DOI: 10.1016/j.ssresearch.2019.102370

Projecting the long-term effects of the COVID-19 pandemic on U.S. population structure

Author(s): Tilstra, Andrea M., Polizzi, A., Wagner, S., Akimova, E.T.
Published in: Nature Communications, 2024, Page(s) 2409, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-46582-4

The interplay between male fertility, mental health and sexual function

Author(s): Vincent J. Straub, Melinda C. Mills
Published in: Nature Reviews Urology, Issue 22, 2025, Page(s) 1-2, ISSN 1759-4812
Publisher: Nature Publishing Group
DOI: 10.1038/s41585-024-00936-1

Gender differences in sleep disruption during COVID-19: cross-sectional analyses from two UK nationally representative surveys

Author(s): Ding, X., Brazel, D.M. & M.C. Mills
Published in: BMJ Open, 2022, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2021-055792

Gene-x-environment analysis supports protective effects of eveningness chronotype on self-reported and actigraphy-derived sleep duration among those who always work night shifts in the UK Biobank

Author(s): Akimova, ET; Taiji, R; Ding, X; Mills, MC
Published in: Sleep, Issue 46, 2023, Page(s) 1-12, ISSN 0049-089X
Publisher: Academic Press
DOI: 10.1093/sleep/zsad023

The challenges of distributing COVID-19 vaccinations.

Author(s): Melinda Mills; David Salisbury
Published in: EClinicalMedicine, Vol 31, Iss , Pp 100674- (2021), Issue 1, 2021, ISSN 2589-5370
Publisher: The Lancet
DOI: 10.1016/j.eclinm.2020.100674

Socio-demographic and epidemiological consideration of Africa’s COVID-19 response: what is the possible pandemic course?

Author(s): Bamba Gaye, Stéphanie Khoury, Crystal W. Cene, Samuel Kingue, Roland N’Guetta, Camille Lassale, Dadhi Baldé, Ibrahima Bara Diop, Jennifer Beam Dowd, Melinda C. Mills, Xavier Jouven
Published in: Nature Medicine, Issue 26, 2023, Page(s) 996-999, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/s41591-020-0960-y

The relationship of major diseases with childlessness: a sibling matched case-control and population register study in Finland and Sweden

Author(s): Aoxing Liu; Evelina T Akimova; Xuejie Ding; Sakari Jukarainen; Pekka Vartiainen; Tuomo Kiiskinen; Sara Kuitunen; Aki S Havulinna; Mika Gissler; Stefano Lombardi; Tove Fall; Melinda C Mills; Andrea Ganna
Published in: Crossref, Issue 1, 2024, ISSN 2397-3374
Publisher: Nature
DOI: 10.1038/s41562-023-01763-x

Reconstructing Sociogenomics Research: Dismantling Biological Race and Genetic Essentialism Narratives

Author(s): Pamela Herd, Melinda C. Mills, Jennifer Beam Dowd
Published in: Journal of Health and Social Behavior, 2021, Page(s) 002214652110186, ISSN 0022-1465
Publisher: SAGE Publications
DOI: 10.1177/00221465211018682

The importance of family-based sampling for biobanks

Author(s): Neil M. Davies, Gibran Hemani, Jenae M. Neiderhiser, Hilary C. Martin, Melinda C. Mills, Peter M. Visscher, Loïc Yengo, Alexander Strudwick Young, Matthew C. Keller
Published in: Nature, Issue 634, 2024, Page(s) 795-803, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-07721-5

The effect of mandatory COVID-19 certificates on vaccine uptake: synthetic-control modelling of six countries

Author(s): Melinda C Mills; Tobias Rüttenauer
Published in: The Lancet. Public Health, Issue 1, 2021, ISSN 2468-2667
Publisher: The Lancet
DOI: 10.1016/s2468-2667(21)00273-5

Realizing the full potential of Our Future Health through data linkage and trans-biobank efforts

Author(s): Vincent J. Straub, Stefania Benonisdottir, Augustine Kong, Melinda C. Mills
Published in: Nature Genetics, Issue 57, 2025, Page(s) 2341-2348, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-025-02327-7

Lack of Trust, Conspiracy Beliefs, and Social Media Use Predict COVID-19 Vaccine Hesitancy

Author(s): Jennings, W. et al, M.C.Mills
Published in: Vaccines, 2021, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9060593

Reply to Nepomuceno et al.: A renewed call for detailed social and demographic COVID-19 data from all countries

Author(s): Jennifer Beam Dowd, Liliana Andriano, David M. Brazel, Valentina Rotondi, Per Block, Xuejie Ding, Melinda C. Mills
Published in: Proceedings of the National Academy of Sciences, Issue 117/25, 2020, Page(s) 13884-13885, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2009408117

Demographic science aids in understanding the spread and fatality rates of COVID-19

Author(s): Jennifer Beam Dowd, Liliana Andriano, David M. Brazel, Valentina Rotondi, Per Block, Xuejie Ding, Yan Liu, Melinda C. Mills
Published in: Proceedings of the National Academy of Sciences, Issue 117/18, 2020, Page(s) 9696-9698, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2004911117

The GWAS Diversity Monitor tracks diversity by disease in real time

Author(s): Melinda C. Mills, Charles Rahal
Published in: Nature Genetics, Issue 52/3, 2020, Page(s) 242-243, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-020-0580-y

Social network-based distancing strategies to flatten the COVID-19 curve in a post-lockdown world

Author(s): Per Block, Marion Hoffman, Isabel J. Raabe, Jennifer Beam Dowd, Charles Rahal, Ridhi Kashyap, Melinda C. Mills
Published in: Nature Human Behaviour, Issue 4/6, 2020, Page(s) 588-596, ISSN 2397-3374
Publisher: Nature
DOI: 10.1038/s41562-020-0898-6

Non-standard Schedules, Work–Family Conflict, and the Moderating Role of National Labour Context: Evidence from 32 European Countries

Author(s): Riley Taiji, Melinda C Mills
Published in: European Sociological Review, Issue 36/2, 2019, Page(s) 179-197, ISSN 0266-7215
Publisher: Oxford University Press
DOI: 10.1093/esr/jcz048

Forecasting spatial, socioeconomic and demographic variation in COVID-19 health care demand in England and Wales

Author(s): Mark D. Verhagen, David M. Brazel, Jennifer Beam Dowd, Ilya Kashnitsky, Melinda C. Mills
Published in: BMC Medicine, Issue 18/1, 2020, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-020-01646-2

Sociology, Genetics, and the Coming of Age of Sociogenomics

Author(s): Melinda C. Mills, Felix C. Tropf
Published in: Annual Review of Sociology, Issue 46/1, 2020, Page(s) 553-581, ISSN 0360-0572
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-soc-121919-054756

Genetics of female and male reproductive traits and their relationship with health, longevity and consequences for offspring

Author(s): Stefania Benonisdottir, Vincent J. Straub, Augustine Kong, Melinda C. Mills
Published in: Nature Aging, Issue 4, 2025, Page(s) 1745-1759, ISSN 2662-8465
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s43587-024-00733-w

Estimating the burden of the COVID-19 pandemic on mortality, life expectancy and lifespan inequality in England and Wales: a population-level analysis.

Author(s): Aburto, Jose Manuel; Kashyap, Ridhi; Schöley, Jonas; Angus, Colin; Ermisch, John; Mills, Melinda C; Dowd, Jennifer Beam
Published in: Journal of Epidemiology & Community Health, Issue 1, 2021, ISSN 0143-005X
Publisher: British Medical Association
DOI: 10.1136/jech-2020-215505

Should spreading anti-vaccine misinformation be criminalised?

Author(s): Mills, M.C. and J. Sivelä
Published in: British Medical Journal, 2021, ISSN 1759-2151
Publisher: British Medical Association
DOI: 10.1136/bmj.n272

Uncovering Digital Trace Data Biases: Tracking Undercoverage in Web Tracking Data

Author(s): Oriol J. Bosch, Patrick Sturgis, Jouni Kuha, Melanie Revilla
Published in: Communication Methods and Measures, Issue 19, 2025, Page(s) 157-177, ISSN 1931-2458
Publisher: Routledge
DOI: 10.1080/19312458.2024.2393165

<i>Population Studies</i> at 75 years: An empirical review

Author(s): Melinda C. Mills; Charles Rahal
Published in: Population Studies, Issue 1, 2021, Page(s) S7-S25, ISSN 0032-4728
Publisher: Routledge
DOI: 10.1080/00324728.2021.1996624

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

Author(s): Melinda C. Mills, Felix C. Tropf, David M. Brazel, Natalie van Zuydam, Ahmad Vaez, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Wibowo Arindrarto, Philip Awadalla, Alexis Battle, Frank Beutner, Marc Jan Bonder, Dorret I. Boomsma, Mark W. Christiansen, Annique Claringbould, Patrick Deelen, Tõnu Esko, Marie-Julie Favé, Lude Franke, Timothy Frayling, Sina A. Gharib, Greg Gi
Published in: Nature Human Behaviour, 2021, ISSN 2397-3374
Publisher: Springer Nature
DOI: 10.1038/s41562-021-01135-3

Gene-environment dependencies lead to collider bias in models with polygenic scores

Author(s): Evelina T. Akimova, Richard Breen, David M. Brazel, Melinda C. Mills
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-89020-x

Prepayment meters strongly associated with multiple types of deprivation and emergency respiratory hospital admissions: an observational, cross-sectional study

Author(s): Ding, X., Akimova, E.T., Zhao, B., Dederichs, K., M.C. Mills
Published in: Journal of Epidemiology and Community Health, 2024, Page(s) 54-60, ISSN 0143-005X
Publisher: British Medical Association
DOI: 10.1136/jech-2023-220793

COVID-19 vaccination passports

Author(s): Christopher Dye, Melinda C. Mills
Published in: Science, Issue 371, 2024, Page(s) 1184-1184, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abi5245

The challenge of detecting recent natural selection in human populations

Author(s): Mills, M.C. & I. Mathieson
Published in: Proceedings of the National Academy of Science, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2203237119

Monographic books (1)

An Introduction to Statistical Genetic Data Analysis

Author(s): Melinda C. Mills, Nicola Barban, Felix C. Tropf
Published in: MIT Press, 2020, ISBN 9780262538381
Publisher: MIT Press

Book chapters (2)

Sociogenomics: theoretical and empirical challenges of integrating molecular genetics into sociological thinking

Author(s): Mills, M.C.
Published in: Handbook of Sociological Science: Contributions to Rigorous Sociology, 2022, ISBN 9781789909425
Publisher: Edward Elgar
DOI: 10.4337/9781789909432.00022

The future of employment in a post-COVID Europe: Building resilience through a fair social, digital and green economy

Author(s): Mills, M.C.
Published in: A New Era for Europe: How the European Union Can Make the Most of its Pandemic Recovery, Pursue Sustainable Growth, and Promote Global Stability, 2022, Page(s) 79-107, ISBN 978-92-76-47202-5
Publisher: European Union
DOI: 10.2765/11297

Other (1)

Stringent COVID-19 government restrictions were associated with a marked increase in Twitter activity in Europe

Author(s): Joe Millard, Evelina Tamerlanov Akimova, Xuejie Ding, Douglas Leasure, Bo Zhao, Melinda Mills
Published in: SocArXiv, 2025
Publisher: Center for Open Science
DOI: 10.31235/osf.io/g9apk