Unintegrated HIV-1 DNA recruits cGAS via its histone-binding domain to escape innate immunity
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Author(s):
Cyprien Jahan, Lucie Bonnet-Madin, Shinichi Machida, Bijan Sobhian, Suzie Thenin-Houssier, Monsef Benkirane
Published in:
Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher:
National Academy of Sciences
DOI:
10.1073/pnas.2424465122
POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing
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Author(s):
Suzie Thenin-Houssier, Shinichi Machida, Cyprien Jahan, Lucie Bonnet-Madin, Scarlette Abbou, Heng-Chang Chen, Robel Tesfaye, Olivier Cuvier, Monsef Benkirane
Published in:
Science Advances, Issue 9, 2024, ISSN 2375-2548
Publisher:
American Association for the Advancement of Science’s
DOI:
10.1126/sciadv.adh3642
Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome
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Author(s):
Shinichi Machida, David Depierre, Heng-Chang Chen, Suzie Thenin-Houssier, Gaël Petitjean, Cecile M. Doyen, Motoki Takaku, Olivier Cuvier, Monsef Benkirane
Published in:
Proceedings of the National Academy of Sciences, Issue 117/12, 2020, Page(s) 6822-6830, ISSN 0027-8424
Publisher:
National Academy of Sciences
DOI:
10.1073/pnas.1913754117
Faithful to the Marseille tradition: Unique and intriguing—that’s how Marseillevirus packs its DNA
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Author(s):
Shinichi Machida, Joao Diogo Dias, Monsef Benkirane
Published in:
Molecular Cell, Issue 82, 2024, Page(s) 4401-4402, ISSN 1097-2765
Publisher:
Cell Press
DOI:
10.1016/j.molcel.2022.11.001
Condensates, the place to hide self-immunostimulatory RNA
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Author(s):
Monsef Benkirane
Published in:
Molecular Cell, Issue 82, 2024, Page(s) 3754-3755, ISSN 1097-2765
Publisher:
Cell Press
DOI:
10.1016/j.molcel.2022.09.028
