Unexpected connections between a phagocytic machinery and mammalian fertilization

Project Information

Sperm-Egg Phusion

Grant agreement ID: 835243

DOI

10.3030/835243

Project closed

EC signature date 2 May 2019

Start date 1 October 2019

End date 30 September 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 375,00

EU contribution

€ 2 499 375,00

Coordinated by

VIB VZW
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Targeting Efferocytosis in Inflammaging

Author(s): Ivan K.H. Poon, Kodi S. Ravichandran
Published in: Annual Review of Pharmacology and Toxicology, Issue 64, 2024, Page(s) 339-357, ISSN 0362-1642
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-pharmtox-032723-110507

Microbes exploit death-induced nutrient release by gut epithelial cells

Author(s): Christopher J. Anderson, Christopher B. Medina, Brady J. Barron, Laura Karvelyte, Tania Løve Aaes, Irina Lambertz, Justin S. A. Perry, Parul Mehrotra, Amanda Gonçalves, Kelly Lemeire, Gillian Blancke, Vanessa Andries, Farzaneh Ghazavi, Arne Martens, Geert van Loo, Lars Vereecke, Peter Vandenabeele, Kodi S. Ravichandran
Published in: Nature, Issue 596/7871, 2021, Page(s) 262-267, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-03785-9

Clearing Your Mind: Mechanisms of Debris Clearance After Cell Death During Neural Development

Author(s): Kendra E. Liu, Michael H. Raymond, Kodi S. Ravichandran, Sarah Kucenas
Published in: Annual Review of Neuroscience, Issue 45, 2023, Page(s) 177-198, ISSN 0147-006X
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-neuro-110920-022431

Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

Author(s): Bartosz Wiernicki, Sophia Maschalidi, Jonathan Pinney, Sandy Adjemian, Tom Vanden Berghe, Kodi S. Ravichandran, Peter Vandenabeele
Published in: Nature Communications, Issue 13, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-31218-2

Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization

Author(s): Claudia M. Rival, Wenhao Xu, Laura S. Shankman, Sho Morioka, Sanja Arandjelovic, Chang Sup Lee, Karen M. Wheeler, Ryan P. Smith, Lisa B. Haney, Brant E. Isakson, Scott Purcell, Jeffrey J. Lysiak, Kodi S. Ravichandran
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12406-z

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes

Author(s): Sophia Maschalidi, Parul Mehrotra, Burcu N. Keçeli, Hannah K. L. De Cleene, Kim Lecomte, Renée Van der Cruyssen, Pauline Janssen, Jonathan Pinney, Geert van Loo, Dirk Elewaut, Ann Massie, Esther Hoste, Kodi S. Ravichandran
Published in: Nature, Issue 606, 2022, Page(s) 776-784, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04754-6

Drugging the efferocytosis process: concepts and opportunities

Author(s): Parul Mehrotra, Kodi S. Ravichandran
Published in: Nature Reviews Drug Discovery, Issue 21, 2024, Page(s) 601-620, ISSN 1474-1776
Publisher: Nature Publishing Group
DOI: 10.1038/s41573-022-00470-y

Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair

Author(s): Parul Mehrotra, Sophia Maschalidi, Laura Boeckaerts, Christian Maueröder, Rochelle Tixeira, Jonathan Pinney, Javier Burgoa Cardás, Vladimir Sukhov, Yunus Incik, Christopher. J. Anderson, Bing Hu, Burcu N. Keçeli, Amanda Goncalves, Lieselotte Vande Walle, Nina Van Opdenbosch, Alexey Sergushichev, Esther Hoste, Umang Jain, Mohamed Lamkanfi, Kodi S. Ravichandran
Published in: Nature, Issue 631, 2024, Page(s) 207-215, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-07585-9

Defining solute carrier transporter signatures of murine immune cell subsets

Author(s): Tania Løve Aaes, Javier Burgoa Cardás, Kodi S. Ravichandran
Published in: Frontiers in Immunology, Issue 14, 2023, ISSN 1664-3224
Publisher: Frontiers Journals
DOI: 10.3389/fimmu.2023.1276196