Toward the microscopic simulations of cell-like environments.

Project Information

CROWDY

Grant agreement ID: 840395

DOI 10.3030/840395

Project closed

EC signature date 16 April 2019

Start date 1 May 2019

End date 30 April 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 196 707,84

EU contribution € 196 707,84

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

Publications

Peer reviewed articles (3)

Stabilizing or Destabilizing: Simulations of Chymotrypsin Inhibitor 2 under Crowding Reveal Existence of a Crossover Temperature

Author(s): Stepan Timr, Fabio Sterpone
Published in: The Journal of Physical Chemistry Letters, Issue 12/6, 2021, Page(s) 1741-1746, ISSN 1948-7185
Publisher: American Chemical Society
DOI: 10.1021/acs.jpclett.0c03626

The Unfolding Journey of Superoxide Dismutase 1 Barrels under Crowding: Atomistic Simulations Shed Light on Intermediate States and Their Interactions with Crowders

Author(s): Stepan Timr, David Gnutt, Simon Ebbinghaus, Fabio Sterpone
Published in: The Journal of Physical Chemistry Letters, Issue 11/10, 2020, Page(s) 4206-4212, ISSN 1948-7185
Publisher: American Chemical Society
DOI: 10.1021/acs.jpclett.0c00699

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis

Author(s): Phuong H. Nguyen, Ayyalusamy Ramamoorthy, Bikash R. Sahoo, Jie Zheng, Peter Faller, John E. Straub, Laura Dominguez, Joan-Emma Shea, Nikolay V. Dokholyan, Alfonso De Simone, Buyong Ma, Ruth Nussinov, Saeed Najafi, Son Tung Ngo, Antoine Loquet, Mara Chiricotto, Pritam Ganguly, James McCarty, Mai Suan Li, Carol Hall, Yiming Wang, Yifat Miller, Simone Melchionna, Birgit Habenstein, Stepan Timr, Jiaxi
Published in: Chemical Reviews, Issue 121/4, 2021, Page(s) 2545-2647, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.0c01122

Book chapters (1)

Protein thermal stability

Author(s): Stepan Timr, Dominique Madern, Fabio Sterpone
Published in: Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly, Issue 170, 2020, Page(s) 239-272, ISBN 9780128211359
Publisher: Elsevier
DOI: 10.1016/bs.pmbts.2019.12.007