Project description
A cancer-on-chip platform for drug discovery
Three-dimensional cell cultures are emerging as promising models for cancer drug discovery, toxicology as well as preclinical and personalised medicine studies. Apart from their biomimetic nature and reproducibility of results, they also facilitate the reduction of animal experimentation. The EU-funded MImETIC INDiRECT project has developed a microfluidics-based culture system that encompasses a chip chamber coated with an extracellular matrix as well as temperature and oxygen sensors. Importantly, the system uses optimised growth factor culture media and is compatible with imaging equipment. Researchers will employ cell lines to reconstruct in vitro 3D cancer models and promote these versatile cell-on-chip platforms for commercialisation.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
- medical and health sciencesclinical medicineoncology
- medical and health scienceshealth sciencespersonalized medicine
- engineering and technologyother engineering and technologiesmicrotechnologyorgan on a chip
Programme(s)
Funding Scheme
MSCA-IF-EF-SE - Society and Enterprise panel
Coordinator
93100 Montreuil
France
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