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MIcrovascularizED Tumour-on-chip for Cellular ImagiNg of Drug Response and Cell moTility

Project description

A cancer-on-chip platform for drug discovery

Three-dimensional cell cultures are emerging as promising models for cancer drug discovery, toxicology as well as preclinical and personalised medicine studies. Apart from their biomimetic nature and reproducibility of results, they also facilitate the reduction of animal experimentation. The EU-funded MImETIC INDiRECT project has developed a microfluidics-based culture system that encompasses a chip chamber coated with an extracellular matrix as well as temperature and oxygen sensors. Importantly, the system uses optimised growth factor culture media and is compatible with imaging equipment. Researchers will employ cell lines to reconstruct in vitro 3D cancer models and promote these versatile cell-on-chip platforms for commercialisation.

Coordinator

CHERRY BIOTECH
Net EU contribution
€ 196 707,84
Address
2eme Etage, Halls A-b Et C14 Rue De La Beaune
93100 Montreuil
France

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Region
Ile-de-France Ile-de-France Seine-Saint-Denis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 196 707,84