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Biological relevance of the multiple infection unit as a novel target for antiviral development


Human norovirus infection of primary B cells triggers immune activation in vitro

Author(s): Mirabelli C, Jones MK, Young V, Kolawole AO, Owusu I, Shan M, Abuaita B, Grigorova I, Lundy SK, Lyssiotis CA, Ward VK, Karst SM, Wobus CE
Published in: mBio, 2022, ISSN 2161-2129
Publisher: American Society for Microbiology
DOI: 10.1128/mbio.00175-22

Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual

Author(s): Bingyu Yan; Srishti Chakravorty; Carmen Mirabelli; Luopin Wang; Jorge L Trujillo-Ochoa; Daniel Chauss; Dhaneshwar Kumar; Dhaneshwar Kumar; Michail S. Lionakis; Matthew R. Olson; Christiane E. Wobus; Behdad Afzali; Majid Kazemian
Published in: Journal of Virology, 2021, ISSN 1098-5514
Publisher: ASM Journals
DOI: 10.1128/jvi.00294-21

Human Norovirus Efficiently Replicates in Differentiated 3D-Human Intestinal Enteroids

Author(s): Carmen Mirabelli; Nanci Santos-Ferreira; Merritt G. Gillilland; Roberto J. Cieza; Justin A. Colacino; Jonathan Z. Sexton; Johan Neyts; Stefan Taube; Joana Rocha-Pereira; Christiane E. Wobus
Published in: Crossref, Issue 2, 2022, ISSN 1098-5514
Publisher: ASM
DOI: 10.5281/zenodo.7307412

Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.

Author(s): Mirabelli C, Wotring JW, Zhang CJ, McCarty SM, Fursmidt R, Pretto CD, Qiao Y, Zhang Y, Frum T, N Kadambi NS, Amin AT, O’Meara TR, Spence JR, Huang J, Alysandratos KD,Kotton DN, Handelman SK, Wobus CE, Weatherwax KJ, Mashour GA, O’Meara MJ, Chinnaiyan AM, and Sexton JZ
Published in: Proceedings of the national academy of Science, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2105815118

Identification of ACE2 modifiers by CRISPR screening.

Author(s): Sherman EJ, Mirabelli C, Tang VT, Khan TG, Kennedy AA, Graham SE, Willer CJ, Tai AW, Sexton JZ, Wobus CE, Emmer BT
Published in: Plos Pathogen, 2022, ISSN 1553-7366
Publisher: Public Library of Science
DOI: 10.1371/journal.ppat.1010377

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