Development of an in silico model for prediction of in vivo human bone fracture healing using micro-finite element analysis

Project Information

HealinguFE

Grant agreement ID: 841316

DOI 10.3030/841316

Project terminated on 31 October 2021

EC signature date 23 April 2019

Start date 1 January 2020

End date 31 December 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 191 149,44

EU contribution € 191 149,44

Coordinated by

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

Publications

Conference proceedings (3)

3D physiological load estimation based on time-lapsed HR-pQCT images

Author(s): M. Walle, F. C. Marques, N. Ohs, R. M¨uller, and C. J. Collins.
Published in: JBMR, Issue Vol 35; Issue 1, 2020, Page(s) 143-144
Publisher: Elsevier

Operator-​independent Characterization of Image Quality in HR-​pQCT Scans using a Fully Automated Convolutional Neural Network-​based Classification Method.

Author(s): Eggemann, D., Walle, M., Atkins, R.P., Stock, K., Müller, R. and Collins, C.J.
Published in: JBMR, 2021
Publisher: Elsevier

Tissue-level mechanical stimuli drive bone formation and resorption in humans and mice

Author(s): Matthias Walle, Francisco C. Marques, Nicholas Ohs, Michael Blauth, Ralph Müller, Caitlyn J. Collins
Published in: Bone Reports, Issue Vol 14; Supplement, 2021, Page(s) 101032, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.101032

Peer reviewed articles (5)

Bone Mechanoregulation Allows Subject-Specific Load Estimation Based on Time-Lapsed Micro-CT and HR-pQCT in Vivo

Author(s): Matthias Walle; Francisco C. Marques; Nicholas Ohs; Michael Blauth; Ralph Müller; Caitlyn J. Collins
Published in: Frontiers in Bioengineering and Biotechnology, Issue Vol 9, 2021, Page(s) 677985, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2021.677985

Automated Segmentation of Fractured Distal Radii by 3D Geodesic ActiveContouring of in vivo HR-pQCT Images

Author(s): Nicholas Ohs; Caitlyn J Collins; Duncan C Tourolle; Penny R Atkins; Bryant J Schroeder; Michael Blauth; Patrik Christen; Ralph Müller
Published in: Bone, Issue Vol 147, 2021, Page(s) 115930, ISSN 8756-3282
Publisher: Elsevier BV
DOI: 10.1016/j.bone.2021.115930

Formation Dominates Resorption With Increasing Mineralized Density and Time Postfracture in Cortical but Not Trabecular Bone: A Longitudinal HRpQCT Imaging Study in the Distal Radius

Author(s): Penny R Atkins; Kerstin Stock; Nicholas Ohs; Caitlyn J Collins; Lukas Horling; Stefan Benedikt; Gerald Degenhart; Kurt Lippuner; Michael Blauth; Patrik Christen; Ralph Müller
Published in: JBMR Plus, Issue Vol 5; Issue 6, 2021, Page(s) e10493, ISSN 2473-4039
Publisher: Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research
DOI: 10.1002/jbm4.10493

Validation of HR-pQCT against micro-CT for morphometric and biomechanical analyses: A review.

Author(s): Nicholas Ohs; Caitlyn J. Collins; Penny R. Atkins
Published in: Bone Reports, Issue Vol 13, 2020, Page(s) 100711, ISSN 2352-1872
Publisher: Elsevier Inc.
DOI: 10.1016/j.bonr.2020.100711

Evaluation of experimental, analytical, and computational methods to determine long-bone bending stiffness

Author(s): Caitlyn J. Collins; Caitlyn J. Collins; Baixuan Yang; Baixuan Yang; Thomas D. Crenshaw; Heidi-Lynn Ploeg; Heidi-Lynn Ploeg
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue Vol 115, 2020, Page(s) 104253, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2020.104253