The amygdala and the treatment of mood disorders
Depression, anxiety and nearly all other mental disorders are associated with a neuromodulatory imbalance in specific sub-circuits. As such, the treatment of mood disorders requires a deeper understanding of the different neuromodulatory inputs to specific brain regions. The EU-funded AmygdalaNeuroMod project will focus on the amygdala, which plays a key role in the regulation of emotions. Specifically, the project will study the functional role of neuromodulatory inputs to the amygdala circuitry in the processes of learning and decision-making. The findings will shed light on the logic of interactions between neuromodulators and their implementation at the level of defined circuits and cell types in the amygdala.