Development of Kinetoplastida Flap Endonuclease Inhibitors in Search for Novel Therapeutics

Project Information

FEN INHIBITORS

Grant agreement ID: 843245

DOI

10.3030/843245

Project closed

EC signature date 30 April 2019

Start date 1 February 2020

End date 31 January 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 319 400,64

EU contribution

€ 319 400,64

Coordinated by

THE UNIVERSITY OF SHEFFIELD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust

Author(s): Hayley Colton, David Hodgson, Hailey Hornsby, Rebecca Brown, Joanne Mckenzie, Kirsty L. Bradley, Cameron James, Benjamin B. Lindsey, Sarah Birch, Louise Marsh, Steven Wood, Martin Bayley, Gary Dickson, David C. James, Martin J. Nicklin, Jon R. Sayers, Domen Zafred, Sarah L. Rowland-Jones, Goura Kudesia, Adam Kucharski, CMMID COVID-19 Working Group, Thomas C. Darton, Thushan I. de Silva, Paul J. Co
Published in: Wellcome Open Research, Issue 2022 Jun 10, 2022, ISSN 2398-502X
Publisher: Welcome Trust
DOI: 10.12688/wellcomeopenres.17143.3

Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy

Author(s): Daniel Michael Williams, Hailey Hornsby, Ola M. Shehata, Rebecca Brown, Marta Gallis, Naomi Meardon, Thomas A.H. Newman, Megan Plowright, Domen Zafred, Amber S.M. Shun-Shion, Anthony J. Hodder, Deepa Bliss, Andrew Metcalfe, James R. Edgar, David E. Gordon, Jon R. Sayers, Martin J.H. Nicklin, Miles W. Carroll, PITCH Consortium, Paul J. Collini, Stephen Brown, Thushan I. de Silva, Andrew A. Peden
Published in: iScience, Issue 21 July 2023, 2023, ISSN 2589-0042
Publisher: Elsevier Publication
DOI: 10.1016/j.isci.2023.107056

Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in <i>Escherichia coli</i>

Author(s): Emma L. Brudenell, Manoj B. Pohare, Domen Zafred, Janine Phipps, Hailey R. Hornsby, John F. Darby, Junxiao Dai, Ellen Liggett, Kathleen M. Cain, Perdita E. Barran, Thushan I. de Silva, Jon R. Sayers
Published in: Biochemical Journal, Issue 481, 2024, Page(s) 669-682, ISSN 0264-6021
Publisher: Portland Press, Ltd.
DOI: 10.1042/bcj20240019