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Cartilage progenitor cells for growth plate regeneration

Project description

Growth plate cartilage restoration

Growth plate injuries are responsible for growth arrest, formation of a ‘bony bar’ and angular limb deformities in children. New therapeutic methods for preventing bone formation and growth arrest need to integrate cellular grafts, biomaterials, and growth factors to recapitulate the complex zonal organisation of the growth plate. The resting zone of the growth plate represents one endogenous source of cartilage progenitor cells. The EU-funded Grolaries project will classify and detect these cells during postnatal growth and in reaction to trauma. The project aims to understand whether resting zone cells express skeletal stem cells characteristics, are expandable and multipotent, and contribute to the regeneration of the growth plate in a physeal fracture model.

Coordinator

UNIVERSIDAD DE OVIEDO
Net EU contribution
€ 204 415,68
Address
Calle San Francisco 3
33003 Oviedo
Spain

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Region
Principado de Asturias Asturias
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Partners (1)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

PRESIDENT AND FELLOWS OF HARVARD COLLEGE
United States
Net EU contribution
€ 0,00
Address
Massachusetts Avenue 1350
02138 Cambridge

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 123 949,44