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Design of multifunctional phosphorous dendritic systems for drug delivery

Objective

The aim of the project is to provide the interdisciplinary training to young talented researcher Dr. Evgeny Apartsin, specialist in biomaterials science and nucleic acid therapy, to become highly qualified world class researcher. The Applicant proposes an interdisciplinary approach for the design of multifunctional phosphorous dendritic systems for the delivery of therapeutic nucleic acids in vitro and in vivo. During the project implementation, novel stimuli-sensitive supramolecular constructions based on phosphorous dendrimers and dendrons will be created to be used as carriers for chemodrugs and nucleic acids. The synthetic part of work will be done in the Host organization, which is world leading institution in the dendrimer science and applications. The physics-chemical and biological parts will be done in collaboration with the Partner organization together with recognized specialists in biophysics, molecular and cell biology. At the last stage of the project, the synthesis of best candidate therapeutic constructions will be transferred to the industry. The Applicant will receive numerous scientific trainings from the experts in macromolecules and medicinal chemistry, molecular biology and industrial technology as well as additional trainings on project management and funding, public dissemination of results, presenting and teaching. The trainings and the implementation of this project (knowledge, skills, papers, patents, etc.) will help the Applicant to be efficiently integrated into the European and international science at highest level.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2018

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Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 196 707,84
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 196 707,84
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