Gut-on-a-chip for microbiota analysis
The gut microbiota comprise all the microorganisms present in the human intestine, providing nutrients and energy for the host. Evidence from both mouse and human studies, including faecal microbiota transplantation, underscores the role of diverse microbiota in overall health. The key objective of the EU-funded Goc-MM project is to develop an artificial intestine-based assay that can be employed to assess human microbiota composition. Researchers will generate a gut-on-a-chip experimental model of epithelial cells that supports the culture of human microbiota. The system is user friendly and can be implemented in the analysis of human faecal microbiota in transplantation cases.