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Principles underlying information flow across the entire brain of the zebrafish

Project description

The mechanism of information flow across the brain

Neurons in the brain form neuronal assemblies, larger functional structures that communicate to deliver information flow and generate motor behaviour and cognitive function. However, the precise mechanism by which the information flows within brain neuronal assemblies remains elusive. The EU-funded BrainInformationFlow project will employ zebrafish larva as the experimental model for studying whole-brain dynamics. Researchers will employ optogenetics and microscopy to unveil the structure and organisation of brain connectivity. Emphasis will be given to the robustness of brain circuits and the compensatory mechanisms in case of interruption of information flow. Project results have the potential to disclose important knowledge on the pathological mechanisms underlying neurological diseases.

Coordinator

ECOLE NORMALE SUPERIEURE
Net EU contribution
€ 196 707,84
Address
45, Rue D'ulm
75230 Paris Cedex 05
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00