Endothelial Cell Molecular and Metabolic Heterogeneity in Pulmonary Arterial Hypertension

Project Information

EMPAtHy

Grant agreement ID: 846615

DOI 10.3030/846615

Project closed

EC signature date 9 April 2019

Start date 1 September 2019

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 166 320,00

EU contribution € 166 320,00

Coordinated by

VIB VZW
Belgium

Publications

Peer reviewed articles (8)

Metabolic Signatures of Distinct Endothelial Phenotypes

Author(s): Sébastien J. Dumas, Melissa García-Caballero, Peter Carmeliet
Published in: Trends in Endocrinology & Metabolism, Issue 31/8, 2020, Page(s) 580-595, ISSN 1043-2760
Publisher: Elsevier BV
DOI: 10.1016/j.tem.2020.05.009

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

Author(s): Sébastien J. Dumas, Elda Meta, Mila Borri, Jermaine Goveia, Katerina Rohlenova, Nadine V. Conchinha, Kim Falkenberg, Laure-Anne Teuwen, Laura de Rooij, Joanna Kalucka, Rongyuan Chen, Shawez Khan, Federico Taverna, Weisi Lu, Magdalena Parys, Carla De Legher, Stefan Vinckier, Tobias K. Karakach, Luc Schoonjans, Lin Lin, Lars Bolund, Mieke Dewerchin, Guy Eelen, Ton J. Rabelink, Xuri Li, Yonglun Luo,
Published in: Journal of the American Society of Nephrology, Issue 31/1, 2019, Page(s) 118-138, ISSN 1046-6673
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2019080832

Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver

Author(s): Liliana Sokol, Vincent Geldhof, Melissa García-Caballero, Nadine V. Conchinha, Sébastien J. Dumas, Elda Meta, Laure-Anne Teuwen, Koen Veys, Rongyuan Chen, Lucas Treps, Mila Borri, Pauline de Zeeuw, Kim D. Falkenberg, Charlotte Dubois, Magdalena Parys, Laura P.M.H. de Rooij, Jermaine Goveia, Katerina Rohlenova, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Xuri Li, Joanna Kalucka, Peter Carmeliet
Published in: STAR Protocols, Issue 2/2, 2021, Page(s) 100489, ISSN 2666-1667
Publisher: Cell Press Elsevier Inc.
DOI: 10.1016/j.xpro.2021.100489

Tumor vessel co-option probed by single-cell analysis

Author(s): Laure-Anne Teuwen, Laura P.M.H. De Rooij, Anne Cuypers, Katerina Rohlenova, Sébastien J. Dumas, Melissa García-Caballero, Elda Meta, Jacob Amersfoort, Federico Taverna, Lisa M. Becker, Nuphar Veiga, Anna Rita Cantelmo, Vincent Geldhof, Nadine V. Conchinha, Joanna Kalucka, Lucas Treps, Lena-Christin Conradi, Shawez Khan, Tobias K. Karakach, Stefaan Soenen, Stefan Vinckier, Luc Schoonjans, Guy Eel
Published in: Cell Reports, Issue 35/11, 2021, Page(s) 109253, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.109253

Phenotypic diversity and metabolic specialization of renal endothelial cells

Author(s): Sébastien J. Dumas, Elda Meta, Mila Borri, Yonglun Luo, Xuri Li, Ton J. Rabelink, Peter Carmeliet
Published in: Nature Reviews Nephrology, Issue 17/7, 2021, Page(s) 441-464, ISSN 1759-5061
Publisher: Nature Publishing Group
DOI: 10.1038/s41581-021-00411-9

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Author(s): Joanna Kalucka, Laura P.M.H. de Rooij, Jermaine Goveia, Katerina Rohlenova, Sébastien J. Dumas, Elda Meta, Nadine V. Conchinha, Federico Taverna, Laure-Anne Teuwen, Koen Veys, Melissa García-Caballero, Shawez Khan, Vincent Geldhof, Liliana Sokol, Rongyuan Chen, Lucas Treps, Mila Borri, Pauline de Zeeuw, Charlotte Dubois, Tobias K. Karakach, Kim D. Falkenberg, Magdalena Parys, Xiangke Yin, Stefan
Published in: Cell, Issue 180/4, 2020, Page(s) 764-779.e20, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2020.01.015

Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis

Author(s): Sébastien J. Dumas, Elda Meta, Nadine V. Conchinha, Liliana Sokol, Rongyuan Chen, Mila Borri, Laure-Anne Teuwen, Koen Veys, Melissa García-Caballero, Vincent Geldhof, Lucas Treps, Pauline de Zeeuw, Kim D. Falkenberg, Charlotte Dubois, Magdalena Parys, Laura P.M.H. de Rooij, Katerina Rohlenova, Jermaine Goveia, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Xuri Li, Joanna Kalucka, Peter Carmeliet
Published in: STAR Protocols, Issue 2/3, 2021, Page(s) 100523, ISSN 2666-1667
Publisher: Cell Press Elsevier Inc.
DOI: 10.1016/j.xpro.2021.100523

Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle

Author(s): Nadine V. Conchinha, Liliana Sokol, Laure-Anne Teuwen, Koen Veys, Sébastien J. Dumas, Elda Meta, Melissa García-Caballero, Vincent Geldhof, Rongyuan Chen, Lucas Treps, Mila Borri, Pauline de Zeeuw, Kim D. Falkenberg, Charlotte Dubois, Magdalena Parys, Laura P.M.H. de Rooij, Katerina Rohlenova, Jermaine Goveia, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Xuri Li, Joanna Kalucka, Peter Carmeliet
Published in: STAR Protocols, Issue 2/3, 2021, Page(s) 100508, ISSN 2666-1667
Publisher: Cell Press Elsevier Inc
DOI: 10.1016/j.xpro.2021.100508